Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL094C
Length:
371
Number of sequences:
5887
Description:
YIL094C LYS12 SGDID:S000001356, Chr IX from 187632-186517, Genome Release 64-1-1, reverse complement, Verified ORF, "Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine, in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31O13696    356   IDH1_SCHPO Isocitrate dehydrogenase [NAD] sub...3741e-54     189     36     53GO:0005759; C:mitochondrial matrix; ISS:PomBase.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IMP:PomBase.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006537; P:glutamate biosynthetic process; IMP:PomBase.::GO:0006102; P:isocitrate metabolic process; IMP:PomBase.::GO:0006099; P:tricarboxylic acid cycle; IMP:PomBase.
32P29696    357   LEU3_SOLTU 3-isopropylmalate dehydrogenase, c...3561e-54     189     34     53GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
33Q8EN68    366   LEU3_OCEIH 3-isopropylmalate dehydrogenase OS...3652e-54     189     39     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
34O13302    388   IDH1_AJECA Isocitrate dehydrogenase [NAD] sub...3507e-54     188     36     55GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
35Q9K8E9    363   LEU3_BACHD 3-isopropylmalate dehydrogenase OS...3631e-53     186     36     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
36Q44471    364   TTUC1_AGRVI Probable tartrate dehydrogenase/d...3642e-53     186     38     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046553; F:D-malate dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050319; F:tartrate decarboxylase activity; IEA:EC.::GO:0009027; F:tartrate dehydrogenase activity; IEA:EC.
37O94230    368   IDH2_KLULA Isocitrate dehydrogenase [NAD] sub...3902e-53     186     35     52GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
38O94229    361   IDH1_KLULA Isocitrate dehydrogenase [NAD] sub...3502e-53     186     37     53GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
39Q8DPJ4    345   LEU3_STRR6 3-isopropylmalate dehydrogenase OS...3583e-53     185     37     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
40O34296    358   TTUC3_AGRVI Probable tartrate dehydrogenase/d...3644e-53     185     38     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046553; F:D-malate dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050319; F:tartrate decarboxylase activity; IEA:EC.::GO:0009027; F:tartrate dehydrogenase activity; IEA:EC.
41Q48K97    360   LEU3_PSE14 3-isopropylmalate dehydrogenase OS...3754e-53     185     37     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
42Q4ZUZ4    360   LEU3_PSEU2 3-isopropylmalate dehydrogenase OS...3755e-53     185     37     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
43Q8PH05    357   LEU3_XANAC 3-isopropylmalate dehydrogenase OS...3576e-53     185     38     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
44Q2G4X5    352   LEU3_NOVAD 3-isopropylmalate dehydrogenase OS...3696e-53     184     38     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
45Q5NPQ9    349   LEU3_ZYMMO 3-isopropylmalate dehydrogenase OS...3636e-53     184     38     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
46Q88LE5    360   LEU3_PSEPK 3-isopropylmalate dehydrogenase OS...3687e-53     185     37     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
47O34295    358   TTUC5_AGRVI Probable tartrate dehydrogenase/d...3688e-53     184     38     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046553; F:D-malate dehydrogenase (decarboxylating) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050319; F:tartrate decarboxylase activity; IEA:EC.::GO:0009027; F:tartrate dehydrogenase activity; IEA:EC.
48Q2IJK7    353   LEU3_ANADE 3-isopropylmalate dehydrogenase OS...3692e-52     183     36     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
49Q3BPJ8    357   LEU3_XANC5 3-isopropylmalate dehydrogenase OS...3542e-52     184     37     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
50Q5SIY4    345   LEU3_THET8 3-isopropylmalate dehydrogenase OS...3662e-52     183     37     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
51Q3KF21    360   LEU3_PSEPF 3-isopropylmalate dehydrogenase OS...3682e-52     184     37     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
52Q2RGA0    357   LEU3_MOOTA 3-isopropylmalate dehydrogenase OS...3442e-52     183     36     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
53Q4KF05    360   LEU3_PSEF5 3-isopropylmalate dehydrogenase OS...3683e-52     183     37     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
54P61494    345   LEU3_THET2 3-isopropylmalate dehydrogenase OS...3664e-52     182     36     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
55P59028    352   LEU3_CHLTE 3-isopropylmalate dehydrogenase OS...3635e-52     182     35     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
56Q30WD0    358   LEU3_DESDG 3-isopropylmalate dehydrogenase OS...3429e-52     182     38     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
57Q46LE2    359   LEU3_PROMT 3-isopropylmalate dehydrogenase OS...3591e-51     181     38     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
58P61495    345   LEU3_THETH 3-isopropylmalate dehydrogenase OS...3661e-51     181     37     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
59Q3AEQ2    374   LEU3_CARHZ 3-isopropylmalate dehydrogenase OS...3482e-51     181     36     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
60Q5H4C7    357   LEU3_XANOR 3-isopropylmalate dehydrogenase OS...3543e-51     181     36     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
61Q2P762    357   LEU3_XANOM 3-isopropylmalate dehydrogenase OS...3543e-51     181     36     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
records
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