Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL074C
Length:
469
Number of sequences:
5887
Description:
YIL074C SER33 SGDID:S000001336, Chr IX from 222490-221081, Genome Release 64-1-1, reverse complement, Verified ORF, "3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser3p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q9Z2F5    430   CTBP1_RAT C-terminal-binding protein 1 OS=Rat...2714e-31     127     34     50GO:0005829; C:cytosol; IDA:RGD.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0051287; F:NAD binding; IDA:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:RGD.::GO:0016746; F:transferase activity, transferring acyl groups; TAS:RGD.
GO:0006944; P:cellular membrane fusion; TAS:RGD.::GO:0007030; P:Golgi organization; IMP:RGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB.
62O88712    441   CTBP1_MOUSE C-terminal-binding protein 1 OS=M...2715e-31     127     34     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; IDA:UniProtKB.
63Q13363    440   CTBP1_HUMAN C-terminal-binding protein 1 OS=H...2716e-31     127     34     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0090241; P:negative regulation of histone H4 acetylation; IMP:BHF-UCL.::GO:0031065; P:positive regulation of histone deacetylation; IMP:BHF-UCL.::GO:0006468; P:protein phosphorylation; TAS:ProtInc.::GO:0051726; P:regulation of cell cycle; IMP:BHF-UCL.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:BHF-UCL.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB.
64P26298    332   LDHD_LACPE D-lactate dehydrogenase OS=Lactoba...2661e-30     125     31     52
GO:0008720; F:D-lactate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
65P56545    445   CTBP2_HUMAN C-terminal-binding protein 2 OS=H...2714e-30     124     33     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB.
66Q9EQH5    445   CTBP2_RAT C-terminal-binding protein 2 OS=Rat...2717e-30     124     33     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB.
67P56546    445   CTBP2_MOUSE C-terminal-binding protein 2 OS=M...2718e-30     124     33     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:MGI.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; IDA:UniProtKB.
68B5XMZ4    323   GHRB_KLEP3 Glyoxylate/hydroxypyruvate reducta...2848e-30     122     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
69Q9YHU0    440   CTBP1_XENLA C-terminal-binding protein 1 OS=X...2711e-29     123     33     49GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
70Q59642    331   LDHD_PEDAC D-lactate dehydrogenase OS=Pedioco...2511e-29     122     30     54
GO:0008720; F:D-lactate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
71O58320    334   GYAR_PYRHO Glyoxylate reductase OS=NBRC 10013...3221e-29     122     30     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047964; F:glyoxylate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
72A6TFG7    323   GHRB_KLEP7 Glyoxylate/hydroxypyruvate reducta...2843e-29     120     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
73Q1CD80    326   GHRB_YERPN Glyoxylate/hydroxypyruvate reducta...2892e-28     118     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
74Q663W4    326   GHRB_YERPS Glyoxylate/hydroxypyruvate reducta...2892e-28     118     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
75A4TGN1    326   GHRB_YERPP Glyoxylate/hydroxypyruvate reducta...2892e-28     118     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
76A9R4G6    326   GHRB_YERPG Glyoxylate/hydroxypyruvate reducta...2892e-28     118     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
77Q0W9V5    326   GHRB_YERPE Glyoxylate/hydroxypyruvate reducta...2892e-28     118     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
78B2K7F1    326   GHRB_YERPB Glyoxylate/hydroxypyruvate reducta...2892e-28     118     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
79Q1C3K4    326   GHRB_YERPA Glyoxylate/hydroxypyruvate reducta...2892e-28     118     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
80A7FPA2    326   GHRB_YERP3 Glyoxylate/hydroxypyruvate reducta...2892e-28     118     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
81A8G7S7    325   GHRB_SERP5 Glyoxylate/hydroxypyruvate reducta...3062e-28     118     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
82Q07511    381   FDH_SOLTU Formate dehydrogenase, mitochondria...3022e-28     119     29     50GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
83Q9W758    437   CTBP2_XENLA C-terminal-binding protein 2 OS=X...2544e-28     119     32     50GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
84A1JT62    326   GHRB_YERE8 Glyoxylate/hydroxypyruvate reducta...2787e-28     116     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
85B1JH01    326   GHRB_YERPY Glyoxylate/hydroxypyruvate reducta...2898e-28     116     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
86Q54UF7    340   LDHD_DICDI Putative D-lactate dehydrogenase O...2511e-27     116     31     49GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0008720; F:D-lactate dehydrogenase activity; ISS:dictyBase.::GO:0051287; F:NAD binding; ISS:dictyBase.
GO:0019652; P:lactate fermentation to propionate and acetate; ISS:dictyBase.
87A8ARD9    324   GHRB_CITK8 Glyoxylate/hydroxypyruvate reducta...2372e-27     115     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
88Q47748    323   VANH_ENTFA D-specific alpha-keto acid dehydro...2292e-27     115     34     48
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
89A4W577    324   GHRB_ENT38 Glyoxylate/hydroxypyruvate reducta...2752e-27     115     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
90P58000    323   GHRB_ENTAG Glyoxylate/hydroxypyruvate reducta...2333e-27     115     32     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
91B1LJB3    324   GHRB_ECOSM Glyoxylate/hydroxypyruvate reducta...2486e-27     114     31     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
records
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