Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL074C
Length:
469
Number of sequences:
5887
Description:
YIL074C SER33 SGDID:S000001336, Chr IX from 222490-221081, Genome Release 64-1-1, reverse complement, Verified ORF, "3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser3p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P0A544    528   SERA_MYCTU D-3-phosphoglycerate dehydrogenase...2896e-38     149     31     53GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IDA:MTBBASE.
GO:0040007; P:growth; IMP:MTBBASE.::GO:0006564; P:L-serine biosynthetic process; IDA:MTBBASE.::GO:0051289; P:protein homotetramerization; IPI:MTBBASE.
32P0A545    528   SERA_MYCBO D-3-phosphoglycerate dehydrogenase...2896e-38     149     31     53
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:EC.
GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW.
33P45250    315   Y1556_HAEIN Putative 2-hydroxyacid dehydrogen...2901e-37     144     33     52
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
34Q6GEC9    317   Y2389_STAAR Putative 2-hydroxyacid dehydrogen...3032e-37     144     35     54
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
35Q54DP1    334   TKRA_DICDI Probable 2-ketogluconate reductase...3065e-37     143     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008873; F:gluconate 2-dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.
36Q2YYT9    317   Y2178_STAAB Putative 2-hydroxyacid dehydrogen...3031e-36     142     35     54
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
37Q2FVW4    317   Y2577_STAA8 Putative 2-hydroxyacid dehydrogen...3031e-36     142     35     54
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
38Q5HDQ4    317   Y2296_STAAC Putative 2-hydroxyacid dehydrogen...3031e-36     142     35     54
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
39Q2FEI9    317   Y2254_STAA3 Putative 2-hydroxyacid dehydrogen...3031e-36     142     35     54
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
40Q8NV80    317   Y2224_STAAW Putative 2-hydroxyacid dehydrogen...3031e-36     142     35     54
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
41Q6G716    317   Y2196_STAAS Putative 2-hydroxyacid dehydrogen...3031e-36     142     35     54
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
42Q99RW8    317   Y2305_STAAM Putative 2-hydroxyacid dehydrogen...3035e-36     140     35     54
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
43Q7A417    317   Y2098_STAAN Putative 2-hydroxyacid dehydrogen...3035e-36     140     35     54
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
44B1L765    332   GYAR_KORCO Glyoxylate reductase OS=Korarchaeu...3027e-36     140     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047964; F:glyoxylate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
45Q5JEZ2    333   GYAR_PYRKO Glyoxylate reductase OS=(Thermococ...3272e-35     139     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047964; F:glyoxylate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
46Q49ZM5    318   Y606_STAS1 Putative 2-hydroxyacid dehydrogena...3144e-35     137     33     55
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
47Q4L8G4    318   Y752_STAHJ Putative 2-hydroxyacid dehydrogena...3021e-34     135     34     54
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
48Q9P7P8    332   DDH1_SCHPO 2-hydroxyacid dehydrogenase homolo...2492e-33     133     33     52GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
49C5A1V0    334   GYAR_THEGJ Glyoxylate reductase OS=Thermococc...3076e-33     131     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047964; F:glyoxylate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
50Q88VJ2    332   LDHD_LACPL D-lactate dehydrogenase OS=Lactoba...2662e-32     130     32     52
GO:0008720; F:D-lactate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
51P44501    331   DDH_HAEIN 2-hydroxyacid dehydrogenase homolog...2353e-32     129     35     52
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
52Q5HLU4    317   Y1888_STAEQ Putative 2-hydroxyacid dehydrogen...2773e-32     129     36     51
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
53O32264    325   TKRA_BACSU Probable 2-ketogluconate reductase...2833e-32     129     31     51
GO:0008873; F:gluconate 2-dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.
54P17584    333   DHD2_LACPA D-2-hydroxyisocaproate dehydrogena...3173e-32     129     28     48
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
55Q8CNB8    317   Y1879_STAES Putative 2-hydroxyacid dehydrogen...2775e-32     128     36     51
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
56P36234    322   DHGY_HYPME Glycerate dehydrogenase OS=Hyphomi...2816e-32     128     30     50
GO:0008465; F:glycerate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
57Q9P7Q1    332   DDH2_SCHPO 2-hydroxyacid dehydrogenase homolo...2331e-31     127     33     53GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
58Q9YAW4    335   GYAR_AERPE Glyoxylate reductase OS=100138 / K...2911e-31     127     27     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047964; F:glyoxylate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
59P30799    331   DDH_ZYMMO 2-hydroxyacid dehydrogenase homolog...2742e-31     127     31     49
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
60Q0VCQ1    445   CTBP2_BOVIN C-terminal-binding protein 2 OS=B...2713e-31     128     34     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB.
61Q9Z2F5    430   CTBP1_RAT C-terminal-binding protein 1 OS=Rat...2714e-31     127     34     50GO:0005829; C:cytosol; IDA:RGD.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0051287; F:NAD binding; IDA:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:RGD.::GO:0016746; F:transferase activity, transferring acyl groups; TAS:RGD.
GO:0006944; P:cellular membrane fusion; TAS:RGD.::GO:0007030; P:Golgi organization; IMP:RGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB.
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