Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL049W
Length:
253
Number of sequences:
5887
Description:
YIL049W DFG10 SGDID:S000001311, Chr IX from 260158-260919, Genome Release 64-1-1, Verified ORF, "Probable polyprenol reductase that catalyzes conversion of polyprenol to dolichol, the precursor for N-glycosylation; involved in filamentous growth; mutations in human ortholog SRD5A3 confer CDG (Congenital Disorders of Glycosylation)"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40526    253   DFG10_YEAST Probable polyprenol reductase OS=...2530     511     100     100GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; ISS:SGD.
GO:0019408; P:dolichol biosynthetic process; IMP:SGD.::GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; IMP:UniProtKB.::GO:0016095; P:polyprenol catabolic process; IMP:UniProtKB.::GO:0007124; P:pseudohyphal growth; IMP:SGD.
2Q7XUH5    354   POED1_ORYSJ Probable polyprenol reductase 1 O...3183e-16     80.5     27     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
GO:0006629; P:lipid metabolic process; IEA:InterPro.
3A2XWN6    354   POED1_ORYSI Probable polyprenol reductase 1 O...3183e-16     80.5     27     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
GO:0006629; P:lipid metabolic process; IEA:InterPro.
4Q7F0Q2    353   POED2_ORYSJ Probable polyprenol reductase 2 O...3145e-16     79.7     27     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
GO:0006629; P:lipid metabolic process; IEA:InterPro.
5Q9VLP9    326   PORED_DROME Probable polyprenol reductase OS=...2970.000000000000007     75.9     27     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
GO:0019348; P:dolichol metabolic process; ISS:UniProtKB.::GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; ISS:UniProtKB.::GO:0016095; P:polyprenol catabolic process; ISS:UniProtKB.
6B8B6G5    353   POED2_ORYSI Probable polyprenol reductase 2 O...3140.00000000000001     75.5     27     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
GO:0006629; P:lipid metabolic process; IEA:InterPro.
7A8X8R3    309   PORED_CAEBR Probable polyprenol reductase OS=...2770.00000000000003     73.9     29     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
GO:0019348; P:dolichol metabolic process; ISS:UniProtKB.::GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; ISS:UniProtKB.::GO:0016095; P:polyprenol catabolic process; ISS:UniProtKB.
8Q17428    309   PORED_CAEEL Probable polyprenol reductase OS=...3130.00000000000005     73.2     26     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
GO:0019348; P:dolichol metabolic process; ISS:UniProtKB.::GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; ISS:UniProtKB.::GO:0016095; P:polyprenol catabolic process; ISS:UniProtKB.
9Q5RIU9    309   PORED_DANRE Probable polyprenol reductase OS=...2770.000000000009     67     26     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; ISS:UniProtKB.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; ISS:UniProtKB.
GO:0019348; P:dolichol metabolic process; ISS:UniProtKB.::GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; ISS:UniProtKB.::GO:0016095; P:polyprenol catabolic process; ISS:UniProtKB.
10Q9CAH5    320   POED1_ARATH Probable polyprenol reductase 1 O...2680.0000000002     63.5     26     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
GO:0006629; P:lipid metabolic process; IEA:InterPro.
11D2HBV9    318   PORED_AILME Probable polyprenol reductase OS=...2870.000000002     60.5     25     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; ISS:UniProtKB.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; ISS:UniProtKB.
GO:0019348; P:dolichol metabolic process; ISS:UniProtKB.::GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; ISS:UniProtKB.::GO:0016095; P:polyprenol catabolic process; ISS:UniProtKB.
12Q8AVI9    319   PORED_XENLA Probable polyprenol reductase OS=...2910.000000005     59.3     25     41GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; ISS:UniProtKB.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; ISS:UniProtKB.
GO:0019348; P:dolichol metabolic process; ISS:UniProtKB.::GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; ISS:UniProtKB.::GO:0016095; P:polyprenol catabolic process; ISS:UniProtKB.
13Q9H8P0    318   PORED_HUMAN Probable polyprenol reductase OS=...2770.00000001     58.2     26     43GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; IDA:UniProtKB.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IDA:UniProtKB.
GO:0006702; P:androgen biosynthetic process; TAS:Reactome.::GO:0019348; P:dolichol metabolic process; IDA:UniProtKB.::GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; IMP:UniProtKB.::GO:0016095; P:polyprenol catabolic process; IDA:UniProtKB.
14Q9SI62    343   POED2_ARATH Probable polyprenol reductase 2 O...1990.00000002     57.8     27     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
GO:0006629; P:lipid metabolic process; IEA:InterPro.
15O14264    274   YFP9_SCHPO Uncharacterized protein C7D4.09c O...1920.00000002     57.4     31     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
GO:0044255; P:cellular lipid metabolic process; NAS:PomBase.
16Q5RJM1    330   PORED_RAT Probable polyprenol reductase OS=Ra...2990.0000006     53.1     23     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; ISS:UniProtKB.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; ISS:UniProtKB.
GO:0019348; P:dolichol metabolic process; ISS:UniProtKB.::GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; ISS:UniProtKB.::GO:0016095; P:polyprenol catabolic process; ISS:UniProtKB.
17Q9WUP4    330   PORED_MOUSE Probable polyprenol reductase OS=...2990.0000007     52.8     24     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; ISS:UniProtKB.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; ISS:UniProtKB.
GO:0019348; P:dolichol metabolic process; IMP:UniProtKB.::GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; IMP:UniProtKB.::GO:0016095; P:polyprenol catabolic process; IMP:UniProtKB.
18Q0P4J9    308   PORED_XENTR Probable polyprenol reductase OS=...2920.0000008     52.8     24     41GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; ISS:UniProtKB.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; ISS:UniProtKB.
GO:0019348; P:dolichol metabolic process; ISS:UniProtKB.::GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; ISS:UniProtKB.::GO:0016095; P:polyprenol catabolic process; ISS:UniProtKB.
19C7T2J9    330   PORED_MESAU Probable polyprenol reductase OS=...3010.0003     45.1     21     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; ISS:UniProtKB.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; ISS:UniProtKB.
GO:0019348; P:dolichol metabolic process; ISS:UniProtKB.::GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; ISS:UniProtKB.::GO:0016095; P:polyprenol catabolic process; ISS:UniProtKB.
20Q9UT20    282   YFY8_SCHPO Uncharacterized protein C9.08c OS=...790.26     35.8     32     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; IEA:InterPro.
GO:0008202; P:steroid metabolic process; IEA:InterPro.
21Q55C17    300   TECR_DICDI Trans-2,3-enoyl-CoA reductase OS=D...1711.1     33.9     26     44GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IEA:EC.
GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.::GO:0042761; P:very long-chain fatty acid biosynthetic process; ISS:UniProtKB.
22Q38944    262   DET2_ARATH Probable steroid reductase DET2 OS...812     33.1     27     47GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; IEA:InterPro.::GO:0009917; F:sterol 5-alpha reductase activity; IDA:TAIR.
GO:0016132; P:brassinosteroid biosynthetic process; IDA:TAIR.::GO:0010268; P:brassinosteroid homeostasis; IEP:TAIR.
23P24008    259   S5A1_RAT 3-oxo-5-alpha-steroid 4-dehydrogenas...892.8     32.3     26     48GO:0070852; C:cell body fiber; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0043209; C:myelin sheath; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; ISS:UniProtKB.::GO:0033218; F:amide binding; IDA:RGD.::GO:0070402; F:NADPH binding; IDA:RGD.
GO:0006702; P:androgen biosynthetic process; IDA:RGD.::GO:0060348; P:bone development; IEP:RGD.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0071320; P:cellular response to cAMP; IEP:RGD.::GO:0071549; P:cellular response to dexamethasone stimulus; IEP:RGD.::GO:0071872; P:cellular response to epinephrine stimulus; IEP:RGD.::GO:0071392; P:cellular response to estradiol stimulus; IEP:RGD.::GO:0071363; P:cellular response to growth factor stimulus; IEP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0071407; P:cellular response to organic cyclic compound; IEP:RGD.::GO:0009267; P:cellular response to starvation; IEP:RGD.::GO:0071394; P:cellular response to testosterone stimulus; IEP:RGD.::GO:0021987; P:cerebral cortex development; IEP:RGD.::GO:0042747; P:circadian sleep/wake cycle, REM sleep; IEP:RGD.::GO:0016101; P:diterpenoid metabolic process; IEP:RGD.::GO:0030540; P:female genitalia development; IEP:RGD.::GO:0021766; P:hippocampus development; IEP:RGD.::GO:0021854; P:hypothalamus development; IEP:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0030539; P:male genitalia development; IEP:RGD.::GO:0008584; P:male gonad development; IEP:RGD.::GO:0021983; P:pituitary gland development; IEP:RGD.::GO:0042448; P:progesterone metabolic process; IDA:RGD.::GO:0042493; P:response to drug; IMP:RGD.::GO:0032354; P:response to follicle-stimulating hormone stimulus; IEP:RGD.::GO:0060992; P:response to fungicide; IEP:RGD.::GO:0060416; P:response to growth hormone stimulus; IEP:RGD.::GO:0014850; P:response to muscle activity; IEP:RGD.::GO:0042428; P:serotonin metabolic process; IEP:RGD.::GO:0021510; P:spinal cord development; IEP:RGD.::GO:0021794; P:thalamus development; IEP:RGD.::GO:0001655; P:urogenital system development; IEP:RGD.
24Q03101    858   CYAG_DICDI Adenylate cyclase, germination spe...875.2     32     29     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:dictyBase.
GO:0004016; F:adenylate cyclase activity; IMP:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IDA:dictyBase.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0045859; P:regulation of protein kinase activity; TAS:dictyBase.::GO:0006970; P:response to osmotic stress; IGI:dictyBase.::GO:0009847; P:spore germination; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase.
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