Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL046W
Length:
54
Number of sequences:
5887
Description:
YIL046W-A YIL046W-A SGDID:S000028836, Chr IX from 268309-268473, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P39014    640   MET30_YEAST F-box protein MET30 OS=Saccharomy...6400     1333     100     100GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043224; C:nuclear SCF ubiquitin ligase complex; IDA:SGD.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0000087; P:M phase of mitotic cell cycle; IMP:SGD.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0000209; P:protein polyubiquitination; IMP:SGD.::GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IMP:SGD.::GO:0000114; P:regulation of transcription involved in G1 phase of mitotic cell cycle; IMP:SGD.::GO:0046685; P:response to arsenic-containing substance; IDA:SGD.::GO:0046686; P:response to cadmium ion; IDA:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2C5FP68    674   SCONB_ARTOC Probable E3 ubiquitin ligase comp...5692e-164     493     44     61
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3Q4X0A9    696   SCONB_ASPFU Probable E3 ubiquitin ligase comp...810.0000008     55.8     35     56
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4B0XTS1    696   SCONB_ASPFC Probable E3 ubiquitin ligase comp...810.0000008     55.8     35     56
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q00659    678   SCONB_EMENI Probable E3 ubiquitin ligase comp...990.00000000004     69.7     33     58
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6A1DHW6    689   SCONB_NEOFI Probable E3 ubiquitin ligase comp...810.0000007     55.8     35     56
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7A1C7E4    700   SCONB_ASPCL Probable E3 ubiquitin ligase comp...990.00000000004     69.7     32     58
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8D4AM37    663   SCONB_ARTBC Probable E3 ubiquitin ligase comp...5745e-160     482     43     59
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9D4D8P3    663   SCONB_TRIVH Probable E3 ubiquitin ligase comp...5741e-159     481     43     59
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10B8NGT5    706   SCONB_ASPFN Probable E3 ubiquitin ligase comp...6097e-159     480     41     57
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11Q2UFN8    705   SCONB_ASPOR Probable E3 ubiquitin ligase comp...6091e-158     480     41     57
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12Q0CY32    673   SCONB_ASPTN Probable E3 ubiquitin ligase comp...990.00000000004     69.7     32     58
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13B8M7Q5    667   SCONB_TALSN Probable E3 ubiquitin ligase comp...6259e-157     473     40     57
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14A2QCU8    670   SCONB_ASPNC Probable E3 ubiquitin ligase comp...3619e-75     258     38     55
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15B6Q4Z5    660   SCONB_PENMQ Probable E3 ubiquitin ligase comp...6186e-153     463     41     57
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16Q01277    650   SCONB_NEUCR Probable E3 ubiquitin ligase comp...6294e-138     425     37     55
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17B6GZA1    673   SCONB_PENCW Probable E3 ubiquitin ligase comp...6128e-138     425     39     56
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18P87053    605   POF1_SCHPO F-box/WD repeat-containing protein...5571e-117     370     38     53GO:0000152; C:nuclear ubiquitin ligase complex; ISS:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:PomBase.
GO:0030674; F:protein binding, bridging; IPI:PomBase.
GO:0071276; P:cellular response to cadmium ion; IEP:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IPI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
19Q969H0    707   FBXW7_HUMAN F-box/WD repeat-containing protei...640.004     43.9     42     53GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.::GO:2000346; P:negative regulation of hepatocyte proliferation; ISS:BHF-UCL.::GO:0045746; P:negative regulation of Notch signaling pathway; ISS:BHF-UCL.::GO:2000639; P:negative regulation of SREBP-mediated signaling pathway; ISS:BHF-UCL.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:BHF-UCL.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0010883; P:regulation of lipid storage; ISS:BHF-UCL.::GO:0032880; P:regulation of protein localization; ISS:BHF-UCL.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:BHF-UCL.::GO:0001944; P:vasculature development; TAS:BHF-UCL.
20Q8VBV4    629   FBXW7_MOUSE F-box/WD repeat-containing protei...640.006     43.1     42     53GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
GO:0007219; P:Notch signaling pathway; IDA:MGI.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
21Q9VZF4    1326   FBXW7_DROME F-box/WD repeat-containing protei...1893e-24     112     33     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; NAS:FlyBase.
GO:0030332; F:cyclin binding; TAS:FlyBase.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0008054; P:cyclin catabolic process; TAS:FlyBase.::GO:0042023; P:DNA endoreduplication; IMP:FlyBase.::GO:0060253; P:negative regulation of glial cell proliferation; IGI:FlyBase.::GO:0045926; P:negative regulation of growth; IMP:FlyBase.::GO:0007096; P:regulation of exit from mitosis; TAS:FlyBase.::GO:0007088; P:regulation of mitosis; IMP:FlyBase.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase.
22Q9UKB1    542   FBW1B_HUMAN F-box/WD repeat-containing protei...890.00008     49.3     30     54GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; ISS:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
23Q5SRY7    542   FBW1B_MOUSE F-box/WD repeat-containing protei...890.00008     49.3     30     54GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IMP:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
24Q3ULA2    605   FBW1A_MOUSE F-box/WD repeat-containing protei...1540.000004     53.5     27     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.
GO:0060444; P:branching involved in mammary gland duct morphogenesis; IMP:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0051726; P:regulation of cell cycle; IMP:MGI.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
25Q9Y297    605   FBW1A_HUMAN F-box/WD repeat-containing protei...890.00003     50.8     31     56GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
26Q91854    518   TRCB_XENLA Beta-TrCP OS=Xenopus laevis (Afric...890.00005     50.1     31     56
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
27Q09855    506   POF11_SCHPO F-box/WD repeat-containing protei...2682e-16     86.7     27     44GO:0005829; C:cytosol; IDA:PomBase.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.
28Q8YRI1    1526   YY46_NOSS1 Uncharacterized WD repeat-containi...2126e-22     105     31     52
29Q00808    1356   HETE1_PODAS Vegetative incompatibility protei...640.032     41.2     38     52
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
30Q93794    587   SEL10_CAEEL F-box/WD repeat-containing protei...505.7     33.9     36     54GO:0030424; C:axon; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:WormBase.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0046660; P:female sex differentiation; IMP:UniProtKB.::GO:0045746; P:negative regulation of Notch signaling pathway; IGI:UniProtKB.
31Q8YTC2    1258   Y2800_NOSS1 Uncharacterized WD repeat-contain...3266e-33     139     30     50
GO:0043531; F:ADP binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:InterPro.
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