Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL044C
Length:
298
Number of sequences:
5887
Description:
YIL044C AGE2 SGDID:S000001306, Chr IX from 273846-272950, Genome Release 64-1-1, reverse complement, Verified ORF, "ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in Trans-Golgi-Network (TGN) transport; contains C2C2H2 cysteine/histidine motif"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q5ZK62    781   ACAP2_CHICK Arf-GAP with coiled-coil, ANK rep...1932e-19     92.8     34     53
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
32Q5VTM2    703   AGAP9_HUMAN Arf-GAP with GTPase, ANK repeat a...1212e-19     92.4     40     62
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
33Q96P47    875   AGAP3_HUMAN Arf-GAP with GTPase, ANK repeat a...1102e-19     92.8     43     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
34Q99490    1192   AGAP2_HUMAN Arf-GAP with GTPase, ANK repeat a...1212e-19     92.8     40     60GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0043524; P:negative regulation of neuron apoptotic process; IGI:MGI.::GO:0042177; P:negative regulation of protein catabolic process; IDA:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
35Q6IVG4    778   ACAP2_RABIT Arf-GAP with coiled-coil, ANK rep...1233e-19     91.7     41     59
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
36A8MT82    671   CTLFB_HUMAN Putative centaurin-gamma-like fam...1214e-19     91.3     40     62
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
37Q8VHH5    910   AGAP3_MOUSE Arf-GAP with GTPase, ANK repeat a...1105e-19     91.3     43     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
38A6NIR3    686   AGAP5_HUMAN Arf-GAP with GTPase, ANK repeat a...1216e-19     90.9     40     62
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
39Q15057    778   ACAP2_HUMAN Arf-GAP with coiled-coil, ANK rep...1237e-19     90.9     41     59
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
40Q15027    740   ACAP1_HUMAN Arf-GAP with coiled-coil, ANK rep...1141e-18     89.7     44     62
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0004629; F:phospholipase C activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006629; P:lipid metabolic process; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
41A5PK26    745   ACAP1_BOVIN Arf-GAP with coiled-coil, ANK rep...1141e-18     89.7     44     62
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
42Q8K2H4    740   ACAP1_MOUSE Arf-GAP with coiled-coil, ANK rep...1142e-18     89.4     44     62
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0004629; F:phospholipase C activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
43O75689    374   ADAP1_HUMAN Arf-GAP with dual PH domain-conta...1174e-18     86.7     41     63GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0008060; F:ARF GTPase activator activity; IDA:UniProtKB.::GO:0043533; F:inositol 1,3,4,5 tetrakisphosphate binding; TAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
44Q9FIT8    828   AGD1_ARATH ADP-ribosylation factor GTPase-act...925e-17     85.1     49     62GO:0030139; C:endocytic vesicle; IDA:TAIR.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; IMP:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
45Q9JK15    376   ADAP2_RAT Arf-GAP with dual PH domain-contain...1212e-16     81.6     40     60GO:0005829; C:cytosol; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005740; C:mitochondrial envelope; IDA:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005545; F:1-phosphatidylinositol binding; IMP:RGD.::GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0043533; F:inositol 1,3,4,5 tetrakisphosphate binding; ISS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007507; P:heart development; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
46Q5W7F2    827   AGD3_ARATH ADP-ribosylation factor GTPase-act...894e-16     82.4     47     64GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0030140; C:trans-Golgi network transport vesicle; IDA:TAIR.
GO:0008060; F:ARF GTPase activator activity; IDA:TAIR.::GO:0035091; F:phosphatidylinositol binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009965; P:leaf morphogenesis; IMP:TAIR.::GO:0010087; P:phloem or xylem histogenesis; IMP:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0009733; P:response to auxin stimulus; IMP:TAIR.::GO:0010051; P:xylem and phloem pattern formation; IMP:TAIR.
47Q04412    482   AGE1_YEAST ADP-ribosylation factor GTPase-act...1130.000000000000002     79.7     40     59GO:0005768; C:endosome; IDA:SGD.::GO:0005802; C:trans-Golgi network; IDA:SGD.
GO:0008060; F:ARF GTPase activator activity; IDA:SGD.::GO:0005543; F:phospholipid binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006888; P:ER to Golgi vesicle-mediated transport; IGI:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IGI:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
48Q8R2V5    381   ADAP2_MOUSE Arf-GAP with dual PH domain-conta...1140.000000000000002     79     41     58GO:0005740; C:mitochondrial envelope; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0043533; F:inositol 1,3,4,5 tetrakisphosphate binding; ISS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; ISS:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; ISS:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007507; P:heart development; NAS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
49Q9UUE2    870   CSX2_SCHPO Protein csx2 OS=Schizosaccharomyce...1210.000000000000004     79.3     37     51GO:0005829; C:cytosol; IDA:PomBase.::GO:0005886; C:plasma membrane; IDA:PomBase.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071276; P:cellular response to cadmium ion; IMP:PomBase.::GO:0006886; P:intracellular protein transport; NAS:PomBase.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0046685; P:response to arsenic-containing substance; IMP:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IC:PomBase.
50O82171    395   AGD10_ARATH ADP-ribosylation factor GTPase-ac...720.000000000000004     78.2     46     68GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0009555; P:pollen development; IMP:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
51Q9SMX5    775   AGD4_ARATH ADP-ribosylation factor GTPase-act...870.000000000000004     79     47     67GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
52Q9FIQ0    402   AGD9_ARATH Probable ADP-ribosylation factor G...720.000000000000006     77.8     46     65
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0009737; P:response to abscisic acid stimulus; IDA:TAIR.
53Q9M354    459   AGD6_ARATH Probable ADP-ribosylation factor G...820.000000000000009     77.4     43     62GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
54O94601    321   YC8E_SCHPO Uncharacterized protein C622.14 OS...1180.00000000000001     76.3     34     56GO:0005737; C:cytoplasm; IDA:PomBase.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; ISS:PomBase.
55O80925    456   AGD7_ARATH ADP-ribosylation factor GTPase-act...810.00000000000002     76.3     43     63GO:0005829; C:cytosol; IDA:TAIR.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
56Q9C6C3    776   AGD2_ARATH ADP-ribosylation factor GTPase-act...1010.00000000000003     76.3     44     61GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
57Q8R5G7    1538   ARAP3_MOUSE Arf-GAP with Rho-GAP domain, ANK ...800.00000000000003     76.6     50     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030336; P:negative regulation of cell migration; IDA:MGI.::GO:0035021; P:negative regulation of Rac protein signal transduction; IDA:MGI.::GO:0035024; P:negative regulation of Rho protein signal transduction; IDA:MGI.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.
58P35197    352   GCS1_YEAST ADP-ribosylation factor GTPase-act...710.00000000000004     75.1     44     65GO:0005856; C:cytoskeleton; IMP:SGD.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IPI:SGD.::GO:0005768; C:endosome; IDA:SGD.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; IDA:SGD.
GO:0003779; F:actin binding; IDA:SGD.::GO:0008060; F:ARF GTPase activator activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030037; P:actin filament reorganization involved in cell cycle; IMP:SGD.::GO:0006888; P:ER to Golgi vesicle-mediated transport; IGI:SGD.::GO:0043001; P:Golgi to plasma membrane protein transport; IMP:SGD.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:SGD.
59Q8H100    413   AGD8_ARATH Probable ADP-ribosylation factor G...720.00000000000005     75.1     44     65GO:0005829; C:cytosol; IDA:TAIR.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
60Q28CM8    526   ARFG2_XENTR ADP-ribosylation factor GTPase-ac...900.0000000000001     73.9     40     60GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
61Q8WZ64    1704   ARAP2_HUMAN Arf-GAP with Rho-GAP domain, ANK ...1050.0000000000003     73.6     42     55GO:0005829; C:cytosol; TAS:Reactome.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
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