Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL042C
Length:
394
Number of sequences:
5887
Description:
YIL042C PKP1 SGDID:S000001304, Chr IX from 276292-275108, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial protein kinase involved in negative regulation of pyruvate dehydrogenase complex activity by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp2p and phosphatases Ptc5p and Ptc6p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40530    394   PDK_YEAST [Pyruvate dehydrogenase [lipoamide]...3940     818     100     100GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IMP:SGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:SGD.
2Q2KJG8    412   BCKD_BOVIN [3-methyl-2-oxobutanoate dehydroge...3088e-31     125     29     50GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; ISS:HGNC.
GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0005524; F:ATP binding; ISS:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; ISS:HGNC.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0009083; P:branched chain family amino acid catabolic process; ISS:HGNC.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.]
3Q00972    412   BCKD_RAT [3-methyl-2-oxobutanoate dehydrogena...3081e-30     125     29     50GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; IDA:HGNC.
GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity; IMP:RGD.::GO:0005524; F:ATP binding; IDA:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; IDA:HGNC.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0009083; P:branched chain family amino acid catabolic process; IDA:HGNC.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.]
4O14874    412   BCKD_HUMAN [3-methyl-2-oxobutanoate dehydroge...3082e-30     125     29     50GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; ISS:HGNC.
GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0005524; F:ATP binding; ISS:HGNC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; ISS:HGNC.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0009083; P:branched chain family amino acid catabolic process; ISS:HGNC.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.]
5O55028    412   BCKD_MOUSE [3-methyl-2-oxobutanoate dehydroge...3082e-30     124     29     50GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; ISS:HGNC.
GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0005524; F:ATP binding; ISS:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; ISS:HGNC.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0009083; P:branched chain family amino acid catabolic process; ISS:HGNC.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.]
6Q15120    406   PDK3_HUMAN [Pyruvate dehydrogenase [lipoamide...3654e-23     102     25     44GO:0005759; C:mitochondrial matrix; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.
7Q922H2    415   PDK3_MOUSE [Pyruvate dehydrogenase [lipoamide...3654e-23     103     25     44GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
8Q8BFP9    434   PDK1_MOUSE [Pyruvate dehydrogenase [lipoamide...3621e-21     99.4     25     48GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
9Q63065    434   PDK1_RAT [Pyruvate dehydrogenase [lipoamide]]...3711e-21     99     24     47GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0045254; C:pyruvate dehydrogenase complex; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IDA:RGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0007166; P:cell surface receptor signaling pathway; IMP:RGD.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
10Q15118    436   PDK1_HUMAN [Pyruvate dehydrogenase [lipoamide...3622e-20     95.9     25     48GO:0005759; C:mitochondrial matrix; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
11O70571    412   PDK4_MOUSE [Pyruvate dehydrogenase [lipoamide...3192e-19     92.4     25     47GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:MGI.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; TAS:MGI.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
12Q64536    407   PDK2_RAT [Pyruvate dehydrogenase [lipoamide]]...3724e-19     91.7     23     44GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0045254; C:pyruvate dehydrogenase complex; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IDA:RGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
13O54937    412   PDK4_RAT [Pyruvate dehydrogenase [lipoamide]]...3765e-19     91.3     24     45GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IDA:RGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; TAS:RGD.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
14Q9JK42    407   PDK2_MOUSE [Pyruvate dehydrogenase [lipoamide...3728e-19     90.9     23     44GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
15Q15119    407   PDK2_HUMAN [Pyruvate dehydrogenase [lipoamide...3721e-18     90.1     23     44GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.
16Q9P6P9    425   PDK_SCHPO [Pyruvate dehydrogenase [lipoamide]...2663e-18     89.7     25     49GO:0005967; C:mitochondrial pyruvate dehydrogenase complex; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; ISS:PomBase.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; ISS:PomBase.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
17Q1KMR4    412   PDK4_RHIFE [Pyruvate dehydrogenase [lipoamide...3804e-18     89     25     44GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0042750; P:hibernation; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
18P91622    413   PDK_DROME [Pyruvate dehydrogenase [lipoamide]...3609e-18     87.8     26     44GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
19Q16654    411   PDK4_HUMAN [Pyruvate dehydrogenase [lipoamide...3761e-17     87.4     24     44GO:0005759; C:mitochondrial matrix; TAS:Reactome.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.
20O88345    412   PDK4_SPETR [Pyruvate dehydrogenase [lipoamide...3804e-17     85.9     24     44GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0042750; P:hibernation; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
21O02623    399   PDK_ASCSU [Pyruvate dehydrogenase [lipoamide]...3520.000000000000001     81.3     24     44GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
22Q02332    401   PDHK2_CAEEL Probable [pyruvate dehydrogenase ...3520.000000000002     71.6     23     44GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
23P53170    491   PKP2_YEAST Pyruvate dehydrogenase kinase 2, m...350.002     43.5     49     69GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IMP:SGD.
GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0043086; P:negative regulation of catalytic activity; IMP:SGD.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:SGD.
24Q8NWF3    583   SRRB_STAAW Sensor protein srrB OS=Staphylococ...920.000008     51.6     37     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
25Q6G973    583   SRRB_STAAS Sensor protein srrB OS=Staphylococ...920.000008     51.6     37     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
26Q5HFT1    583   SRRB_STAAC Sensor protein srrB OS=Staphylococ...920.000008     51.6     37     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
27Q2FY80    583   SRRB_STAA8 Sensor protein srrB OS=Staphylococ...920.000008     51.6     37     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
28Q7A5H7    583   SRRB_STAAN Sensor protein srrB OS=Staphylococ...920.000008     51.6     37     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
29Q99TZ9    583   SRRB_STAAM Sensor protein srrB OS=Staphylococ...920.000008     51.6     37     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
30Q6GGK7    583   SRRB_STAAR Sensor protein srrB OS=Staphylococ...920.000008     51.6     37     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
31Q9L523    583   SRRB_STAAU Sensor protein srrB OS=Staphylococ...920.000009     51.2     37     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
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