rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P40530 | 394 | PDK_YEAST [Pyruvate dehydrogenase [lipoamide]... | 394 | 0 | 818 | 100 | 100 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IMP:SGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:SGD. | 2 | Q2KJG8 | 412 | BCKD_BOVIN [3-methyl-2-oxobutanoate dehydroge... | 308 | 8e-31 | 125 | 29 | 50 | GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; ISS:HGNC. | | | | | | | | | | GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0005524; F:ATP binding; ISS:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; ISS:HGNC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; ISS:HGNC.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.] | 3 | Q00972 | 412 | BCKD_RAT [3-methyl-2-oxobutanoate dehydrogena... | 308 | 1e-30 | 125 | 29 | 50 | GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; IDA:HGNC. | | | | | | | | | | GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity; IMP:RGD.::GO:0005524; F:ATP binding; IDA:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; IDA:HGNC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; IDA:HGNC.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.] | 4 | O14874 | 412 | BCKD_HUMAN [3-methyl-2-oxobutanoate dehydroge... | 308 | 2e-30 | 125 | 29 | 50 | GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; ISS:HGNC. | | | | | | | | | | GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0005524; F:ATP binding; ISS:HGNC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; ISS:HGNC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; ISS:HGNC.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.] | 5 | O55028 | 412 | BCKD_MOUSE [3-methyl-2-oxobutanoate dehydroge... | 308 | 2e-30 | 124 | 29 | 50 | GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; ISS:HGNC. | | | | | | | | | | GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0005524; F:ATP binding; ISS:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; ISS:HGNC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; ISS:HGNC.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.] | 6 | Q15120 | 406 | PDK3_HUMAN [Pyruvate dehydrogenase [lipoamide... | 365 | 4e-23 | 102 | 25 | 44 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome. | 7 | Q922H2 | 415 | PDK3_MOUSE [Pyruvate dehydrogenase [lipoamide... | 365 | 4e-23 | 103 | 25 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 8 | Q8BFP9 | 434 | PDK1_MOUSE [Pyruvate dehydrogenase [lipoamide... | 362 | 1e-21 | 99.4 | 25 | 48 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 9 | Q63065 | 434 | PDK1_RAT [Pyruvate dehydrogenase [lipoamide]]... | 371 | 1e-21 | 99 | 24 | 47 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0045254; C:pyruvate dehydrogenase complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IDA:RGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; IMP:RGD.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 10 | Q15118 | 436 | PDK1_HUMAN [Pyruvate dehydrogenase [lipoamide... | 362 | 2e-20 | 95.9 | 25 | 48 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc. | 11 | O70571 | 412 | PDK4_MOUSE [Pyruvate dehydrogenase [lipoamide... | 319 | 2e-19 | 92.4 | 25 | 47 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:MGI.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; TAS:MGI.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 12 | Q64536 | 407 | PDK2_RAT [Pyruvate dehydrogenase [lipoamide]]... | 372 | 4e-19 | 91.7 | 23 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0045254; C:pyruvate dehydrogenase complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IDA:RGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 13 | O54937 | 412 | PDK4_RAT [Pyruvate dehydrogenase [lipoamide]]... | 376 | 5e-19 | 91.3 | 24 | 45 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IDA:RGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; TAS:RGD.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 14 | Q9JK42 | 407 | PDK2_MOUSE [Pyruvate dehydrogenase [lipoamide... | 372 | 8e-19 | 90.9 | 23 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 15 | Q15119 | 407 | PDK2_HUMAN [Pyruvate dehydrogenase [lipoamide... | 372 | 1e-18 | 90.1 | 23 | 44 | GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome. | 16 | Q9P6P9 | 425 | PDK_SCHPO [Pyruvate dehydrogenase [lipoamide]... | 266 | 3e-18 | 89.7 | 25 | 49 | GO:0005967; C:mitochondrial pyruvate dehydrogenase complex; ISS:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; ISS:PomBase.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; ISS:PomBase.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 17 | Q1KMR4 | 412 | PDK4_RHIFE [Pyruvate dehydrogenase [lipoamide... | 380 | 4e-18 | 89 | 25 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0042750; P:hibernation; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 18 | P91622 | 413 | PDK_DROME [Pyruvate dehydrogenase [lipoamide]... | 360 | 9e-18 | 87.8 | 26 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 19 | Q16654 | 411 | PDK4_HUMAN [Pyruvate dehydrogenase [lipoamide... | 376 | 1e-17 | 87.4 | 24 | 44 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome. | 20 | O88345 | 412 | PDK4_SPETR [Pyruvate dehydrogenase [lipoamide... | 380 | 4e-17 | 85.9 | 24 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0042750; P:hibernation; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 21 | O02623 | 399 | PDK_ASCSU [Pyruvate dehydrogenase [lipoamide]... | 352 | 0.000000000000001 | 81.3 | 24 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 22 | Q02332 | 401 | PDHK2_CAEEL Probable [pyruvate dehydrogenase ... | 352 | 0.000000000002 | 71.6 | 23 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 23 | P53170 | 491 | PKP2_YEAST Pyruvate dehydrogenase kinase 2, m... | 35 | 0.002 | 43.5 | 49 | 69 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IMP:SGD. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0043086; P:negative regulation of catalytic activity; IMP:SGD.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:SGD. | 24 | Q8NWF3 | 583 | SRRB_STAAW Sensor protein srrB OS=Staphylococ... | 92 | 0.000008 | 51.6 | 37 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 25 | Q6G973 | 583 | SRRB_STAAS Sensor protein srrB OS=Staphylococ... | 92 | 0.000008 | 51.6 | 37 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 26 | Q5HFT1 | 583 | SRRB_STAAC Sensor protein srrB OS=Staphylococ... | 92 | 0.000008 | 51.6 | 37 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 27 | Q2FY80 | 583 | SRRB_STAA8 Sensor protein srrB OS=Staphylococ... | 92 | 0.000008 | 51.6 | 37 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 28 | Q7A5H7 | 583 | SRRB_STAAN Sensor protein srrB OS=Staphylococ... | 92 | 0.000008 | 51.6 | 37 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 29 | Q99TZ9 | 583 | SRRB_STAAM Sensor protein srrB OS=Staphylococ... | 92 | 0.000008 | 51.6 | 37 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 30 | Q6GGK7 | 583 | SRRB_STAAR Sensor protein srrB OS=Staphylococ... | 92 | 0.000008 | 51.6 | 37 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. | 31 | Q9L523 | 583 | SRRB_STAAU Sensor protein srrB OS=Staphylococ... | 92 | 0.000009 | 51.2 | 37 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro. |