Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL035C
Length:
372
Number of sequences:
5887
Description:
YIL035C CKA1 SGDID:S000001297, Chr IX from 288908-287790, Genome Release 64-1-1, reverse complement, Verified ORF, "Alpha catalytic subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P15790    372   CSK21_YEAST Casein kinase II subunit alpha OS...3720     768     100     100GO:0005956; C:protein kinase CK2 complex; IDA:SGD.::GO:0034456; C:UTP-C complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0006356; P:regulation of transcription from RNA polymerase I promoter; IDA:SGD.::GO:0006359; P:regulation of transcription from RNA polymerase III promoter; IDA:SGD.::GO:0006974; P:response to DNA damage stimulus; IDA:SGD.
2P40231    332   CSK2A_SCHPO Casein kinase II subunit alpha OS...3662e-138     404     56     70GO:0005829; C:cytosol; IDA:PomBase.::GO:0005730; C:nucleolus; IDA:PomBase.::GO:0005956; C:protein kinase CK2 complex; TAS:PomBase.::GO:0031931; C:TORC1 complex; IDA:PomBase.::GO:0031932; C:TORC2 complex; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007163; P:establishment or maintenance of cell polarity; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase.
3P08181    336   CSK2A_DROME Casein kinase II subunit alpha OS...3611e-131     387     59     72GO:0005829; C:cytosol; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0005956; C:protein kinase CK2 complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:FlyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:FlyBase.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0048749; P:compound eye development; IMP:FlyBase.::GO:0046331; P:lateral inhibition; IMP:FlyBase.::GO:0045475; P:locomotor rhythm; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0031397; P:negative regulation of protein ubiquitination; IMP:FlyBase.::GO:0007228; P:positive regulation of hh target transcription factor activity; IMP:FlyBase.::GO:0045880; P:positive regulation of smoothened signaling pathway; IMP:FlyBase.::GO:0031647; P:regulation of protein stability; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; IDA:FlyBase.
4P21869    350   CSK22_CHICK Casein kinase II subunit alpha' O...3617e-131     386     59     71
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
5P21868    391   CSK21_CHICK Casein kinase II subunit alpha OS...3679e-130     384     59     71
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
6P19784    350   CSK22_HUMAN Casein kinase II subunit alpha' O...3611e-129     382     59     70GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
7P28020    392   CSK21_XENLA Casein kinase II subunit alpha OS...3672e-129     383     58     71
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
8Q8TG13    336   CSK2A_NEUCR Casein kinase II subunit alpha OS...3653e-129     381     56     71
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
9P20427    350   CSK22_BOVIN Casein kinase II subunit alpha' O...3617e-129     380     59     70
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
10O54833    350   CSK22_MOUSE Casein kinase II subunit alpha' O...3618e-129     380     59     70GO:0005956; C:protein kinase CK2 complex; TAS:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
11Q60737    391   CSK21_MOUSE Casein kinase II subunit alpha OS...3642e-128     381     59     71GO:0005956; C:protein kinase CK2 complex; TAS:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008013; F:beta-catenin binding; IPI:MGI.::GO:0019888; F:protein phosphatase regulator activity; IDA:MGI.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
12P19139    391   CSK21_RAT Casein kinase II subunit alpha OS=R...3642e-128     381     59     71GO:0005956; C:protein kinase CK2 complex; TAS:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; NAS:RGD.::GO:0042127; P:regulation of cell proliferation; NAS:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
13P68400    391   CSK21_HUMAN Casein kinase II subunit alpha OS...3643e-128     380     59     71GO:0005829; C:cytosol; TAS:Reactome.::GO:0016581; C:NuRD complex; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; TAS:ProtInc.::GO:0016580; C:Sin3 complex; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051879; F:Hsp90 protein binding; TAS:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0061077; P:chaperone-mediated protein folding; TAS:UniProtKB.::GO:0071174; P:mitotic cell cycle spindle checkpoint; IMP:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
14P68399    391   CSK21_BOVIN Casein kinase II subunit alpha OS...3643e-128     380     59     71
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; ISS:AgBase.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
15O76484    353   CSK2A_SPOFR Casein kinase II subunit alpha OS...3677e-127     375     57     71
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
16P33674    391   CSK21_RABIT Casein kinase II subunit alpha OS...3641e-126     376     58     70
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
17Q08467    409   CSK21_ARATH Casein kinase II subunit alpha-1 ...3673e-125     374     56     71
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
18P19454    339   CSK22_YEAST Casein kinase II subunit alpha' O...3628e-125     370     55     66GO:0005956; C:protein kinase CK2 complex; IDA:SGD.::GO:0034456; C:UTP-C complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0001300; P:chronological cell aging; IMP:SGD.::GO:0006356; P:regulation of transcription from RNA polymerase I promoter; IDA:SGD.::GO:0006359; P:regulation of transcription from RNA polymerase III promoter; IDA:SGD.::GO:0006974; P:response to DNA damage stimulus; IDA:SGD.
19O64817    333   CSK23_ARATH Probable casein kinase II subunit...3627e-124     367     56     72
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
20Q08466    403   CSK22_ARATH Casein kinase II subunit alpha-2 ...3649e-124     369     56     71GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
21O64816    432   CSK2P_ARATH Casein kinase II subunit alpha, c...3621e-123     370     57     69GO:0005829; C:cytosol; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
22P28523    332   CSK2A_MAIZE Casein kinase II subunit alpha OS...3623e-122     363     57     69
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
23P18334    360   CSK2A_CAEEL Casein kinase II subunit alpha OS...3634e-121     361     56     70GO:0030424; C:axon; IDA:UniProtKB.::GO:0005929; C:cilium; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0034606; P:response to hermaphrodite contact; IMP:WormBase.::GO:0034608; P:vulval location; IMP:WormBase.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
24Q02720    337   CSK2A_DICDI Casein kinase II subunit alpha OS...3613e-111     335     53     67
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase.
25Q4U925    348   CSK2A_THEAN Casein kinase II subunit alpha OS...3592e-109     331     52     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
26P28547    348   CSK2A_THEPA Casein kinase II subunit alpha OS...3592e-109     331     51     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
27Q54LR6    605   Y6481_DICDI Probable serine/threonine-protein...3632e-98     311     47     62GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
28Q8SRU0    319   CSK2A_ENCCU Probable casein kinase II subunit...3603e-93     288     44     62
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
29Q6FKD4    302   PHO85_CANGA Negative regulator of the PHO sys...3396e-35     135     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
30Q4Y4B1    288   CDC2H_PLACH Cell division control protein 2 h...3242e-34     133     29     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
31Q4Z6R1    288   CDC2H_PLABA Cell division control protein 2 h...3242e-34     133     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
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