Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL035C
Length:
372
Number of sequences:
5887
Description:
YIL035C CKA1 SGDID:S000001297, Chr IX from 288908-287790, Genome Release 64-1-1, reverse complement, Verified ORF, "Alpha catalytic subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61P49615    292   CDK5_MOUSE Cyclin-dependent kinase 5 OS=Mus m...3301e-31     126     27     50GO:0030424; C:axon; ISS:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:MGI.::GO:0030175; C:filopodium; IDA:MGI.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0031594; C:neuromuscular junction; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0030549; F:acetylcholine receptor activator activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; IDA:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IPI:MGI.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0048148; P:behavioral response to cocaine; IMP:MGI.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007160; P:cell-matrix adhesion; IDA:MGI.::GO:0021954; P:central nervous system neuron development; IMP:MGI.::GO:0021697; P:cerebellar cortex formation; IMP:MGI.::GO:0022038; P:corpus callosum development; IMP:MGI.::GO:0048813; P:dendrite morphogenesis; IMP:MGI.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0006886; P:intracellular protein transport; IMP:MGI.::GO:0021819; P:layer formation in cerebral cortex; IMP:MGI.::GO:0008045; P:motor axon guidance; IMP:MGI.::GO:0045786; P:negative regulation of cell cycle; IMP:MGI.::GO:0046826; P:negative regulation of protein export from nucleus; IMP:MGI.::GO:0031397; P:negative regulation of protein ubiquitination; IMP:MGI.::GO:0031914; P:negative regulation of synaptic plasticity; IMP:MGI.::GO:0051402; P:neuron apoptotic process; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IDA:MGI.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; IMP:MGI.::GO:0032801; P:receptor catabolic process; IMP:MGI.::GO:0043113; P:receptor clustering; IMP:MGI.::GO:0030334; P:regulation of cell migration; IMP:MGI.::GO:0061001; P:regulation of dendritic spine morphogenesis; IMP:UniProtKB.::GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IMP:MGI.::GO:0014044; P:Schwann cell development; IMP:MGI.::GO:0019233; P:sensory perception of pain; IMP:MGI.::GO:0033136; P:serine phosphorylation of STAT3 protein; IDA:MGI.::GO:0007519; P:skeletal muscle tissue development; IDA:MGI.::GO:0001963; P:synaptic transmission, dopaminergic; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0008542; P:visual learning; IMP:MGI.
62Q02399    292   CDK5_BOVIN Cyclin-dependent kinase 5 OS=Bos t...3301e-31     126     27     50GO:0030424; C:axon; ISS:AgBase.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:AgBase.::GO:0030175; C:filopodium; ISS:AgBase.::GO:0030426; C:growth cone; ISS:AgBase.::GO:0030027; C:lamellipodium; ISS:AgBase.::GO:0031594; C:neuromuscular junction; ISS:AgBase.::GO:0005634; C:nucleus; ISS:AgBase.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0030549; F:acetylcholine receptor activator activity; ISS:AgBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; ISS:AgBase.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0035173; F:histone kinase activity; TAS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:AgBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007160; P:cell-matrix adhesion; ISS:AgBase.::GO:0009790; P:embryo development; ISS:AgBase.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:AgBase.::GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.
63P34117    292   CDK5_DICDI Cyclin-dependent kinase 5 homolog ...2391e-31     125     33     57GO:0005737; C:cytoplasm; IDA:dictyBase.::GO:0072686; C:mitotic spindle; IDA:dictyBase.::GO:0005654; C:nucleoplasm; IDA:dictyBase.::GO:0005625; C:soluble fraction; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:dictyBase.::GO:0005515; F:protein binding; IPI:dictyBase.
GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0008283; P:cell proliferation; IMP:dictyBase.::GO:0006909; P:phagocytosis; IMP:dictyBase.::GO:0031157; P:regulation of aggregate size involved in sorocarp development; IMP:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IMP:dictyBase.
64Q00535    292   CDK5_HUMAN Cyclin-dependent kinase 5 OS=Homo ...3301e-31     125     28     50GO:0030424; C:axon; ISS:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0031594; C:neuromuscular junction; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0030549; F:acetylcholine receptor activator activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; ISS:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0008633; P:activation of pro-apoptotic gene products; IDA:UniProtKB.::GO:0048675; P:axon extension; TAS:UniProtKB.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:DFLAT.::GO:0051402; P:neuron apoptotic process; TAS:UniProtKB.::GO:0001764; P:neuron migration; TAS:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; IDA:UniProtKB.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; TAS:UniProtKB.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0071156; P:regulation of cell cycle arrest; TAS:UniProtKB.::GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0007416; P:synapse assembly; TAS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; TAS:UniProtKB.::GO:0016079; P:synaptic vesicle exocytosis; TAS:UniProtKB.
65Q38772    294   CDC2A_ANTMA Cell division control protein 2 h...3351e-31     125     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
66Q96287    472   KSG8_ARATH Shaggy-related protein kinase thet...3432e-31     128     28     46GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0009741; P:response to brassinosteroid stimulus; IMP:TAIR.
67O23145    431   KSG2_ARATH Shaggy-related protein kinase beta...3462e-31     127     27     49GO:0005829; C:cytosol; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0046777; P:protein autophosphorylation; IDA:TAIR.
68Q27032    298   CDC2H_THEPA Cell division control protein 2 h...2382e-31     125     33     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
69O04160    468   KSGT_BRANA Shaggy-related protein kinase thet...3422e-31     127     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
70Q26671    298   CDC2H_THEAN Cell division control protein 2 h...2382e-31     125     33     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
71P00546    298   CDK1_YEAST Cyclin-dependent kinase 1 OS=Sacch...3413e-31     124     30     48GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:SGD.::GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:SGD.::GO:0042393; F:histone binding; IDA:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006338; P:chromatin remodeling; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051447; P:negative regulation of meiotic cell cycle; IMP:SGD.::GO:0045930; P:negative regulation of mitotic cell cycle; IDA:SGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:SGD.::GO:0010571; P:positive regulation of DNA replication involved in S phase; IMP:SGD.::GO:0051446; P:positive regulation of meiotic cell cycle; IDA:SGD.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:SGD.::GO:0010696; P:positive regulation of spindle pole body separation; IMP:SGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:SGD.::GO:0010898; P:positive regulation of triglyceride catabolic process; IMP:SGD.::GO:0010568; P:regulation of budding cell apical bud growth; IMP:SGD.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; IMP:SGD.::GO:0010570; P:regulation of filamentous growth; IMP:SGD.
72Q03114    292   CDK5_RAT Cyclin-dependent kinase 5 OS=Rattus ...3303e-31     124     28     49GO:0030424; C:axon; IDA:UniProtKB.::GO:0030054; C:cell junction; TAS:RGD.::GO:0016533; C:cyclin-dependent protein kinase 5 holoenzyme complex; IDA:RGD.::GO:0030426; C:growth cone; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0031594; C:neuromuscular junction; IDA:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0030549; F:acetylcholine receptor activator activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; ISS:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.
GO:0048675; P:axon extension; TAS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030866; P:cortical actin cytoskeleton organization; IMP:RGD.::GO:0009790; P:embryo development; IDA:UniProtKB.::GO:0051402; P:neuron apoptotic process; IMP:RGD.::GO:0006913; P:nucleocytoplasmic transport; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0045055; P:regulated secretory pathway; IMP:RGD.::GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0009611; P:response to wounding; IMP:RGD.::GO:0007519; P:skeletal muscle tissue development; TAS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; IMP:RGD.
73P49840    483   GSK3A_HUMAN Glycogen synthase kinase-3 alpha ...2254e-31     127     35     52GO:0030877; C:beta-catenin destruction complex; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0050321; F:tau-protein kinase activity; TAS:UniProtKB.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0003214; P:cardiac left ventricle morphogenesis; ISS:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; ISS:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; TAS:UniProtKB.::GO:0061052; P:negative regulation of cell growth involved in cardiac muscle cell development; ISS:BHF-UCL.::GO:0046325; P:negative regulation of glucose import; IMP:BHF-UCL.::GO:2000466; P:negative regulation of glycogen (starch) synthase activity; TAS:UniProtKB.::GO:0045719; P:negative regulation of glycogen biosynthetic process; TAS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:BHF-UCL.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:BHF-UCL.::GO:2000077; P:negative regulation of type B pancreatic cell development; TAS:UniProtKB.::GO:0010905; P:negative regulation of UDP-glucose catabolic process; IC:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0071879; P:positive regulation of adrenergic receptor signaling pathway; ISS:BHF-UCL.::GO:0030819; P:positive regulation of cAMP biosynthetic process; ISS:BHF-UCL.::GO:2000467; P:positive regulation of glycogen (starch) synthase activity; ISS:BHF-UCL.::GO:0045823; P:positive regulation of heart contraction; ISS:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; NAS:BHF-UCL.::GO:0003073; P:regulation of systemic arterial blood pressure; ISS:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
74P34112    296   CDK1_DICDI Cyclin-dependent kinase 1 OS=Dicty...3286e-31     124     29     48GO:0005622; C:intracellular; IDA:dictyBase.
GO:0005524; F:ATP binding; IDA:dictyBase.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:dictyBase.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
75P51139    411   MSK3_MEDSA Glycogen synthase kinase-3 homolog...3466e-31     125     28     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
76Q2NL51    490   GSK3A_MOUSE Glycogen synthase kinase-3 alpha ...2258e-31     125     35     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0003214; P:cardiac left ventricle morphogenesis; IMP:BHF-UCL.::GO:0016477; P:cell migration; IGI:MGI.::GO:0071285; P:cellular response to lithium ion; IDA:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0044027; P:hypermethylation of CpG island; IMP:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; IDA:BHF-UCL.::GO:0061052; P:negative regulation of cell growth involved in cardiac muscle cell development; IMP:BHF-UCL.::GO:0032007; P:negative regulation of TOR signaling cascade; IMP:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0071879; P:positive regulation of adrenergic receptor signaling pathway; IMP:BHF-UCL.::GO:0030819; P:positive regulation of cAMP biosynthetic process; IMP:BHF-UCL.::GO:2000467; P:positive regulation of glycogen (starch) synthase activity; IMP:BHF-UCL.::GO:0045823; P:positive regulation of heart contraction; IMP:BHF-UCL.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:MGI.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:BHF-UCL.::GO:0003073; P:regulation of systemic arterial blood pressure; IMP:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
77Q5I6M2    329   HOG1_SETTU Mitogen-activated protein kinase H...2799e-31     124     30     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
78P51138    411   MSK2_MEDSA Glycogen synthase kinase-3 homolog...3419e-31     125     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
79Q03147    346   CDK7_MOUSE Cyclin-dependent kinase 7 OS=Mus m...3511e-30     124     29     48GO:0005675; C:holo TFIIH complex; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008094; F:DNA-dependent ATPase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
80Q39021    370   MPK1_ARATH Mitogen-activated protein kinase 1...3441e-30     124     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:TAIR.
GO:0009734; P:auxin mediated signaling pathway; TAS:TAIR.
81Q4W6D3    355   HOG1_COCHE Mitogen-activated protein kinase H...2791e-30     124     30     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
82P18266    420   GSK3B_RAT Glycogen synthase kinase-3 beta OS=...2261e-30     125     35     51GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:BHF-UCL.::GO:0030877; C:beta-catenin destruction complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:RGD.::GO:0043197; C:dendritic spine; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0005178; F:integrin binding; IPI:RGD.::GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0048156; F:tau protein binding; IDA:RGD.::GO:0050321; F:tau-protein kinase activity; IDA:RGD.
GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; IDA:RGD.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0050774; P:negative regulation of dendrite morphogenesis; IMP:RGD.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:RGD.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; ISS:UniProtKB.::GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:RGD.::GO:0032886; P:regulation of microtubule-based process; ISS:UniProtKB.::GO:0048168; P:regulation of neuronal synaptic plasticity; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0010226; P:response to lithium ion; IEP:RGD.
83O61443    365   MK14B_DROME Mitogen-activated protein kinase ...3302e-30     124     27     51GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016909; F:SAP kinase activity; NAS:FlyBase.
GO:0071243; P:cellular response to arsenic-containing substance; IDA:FlyBase.::GO:0071276; P:cellular response to cadmium ion; IDA:FlyBase.::GO:0034614; P:cellular response to reactive oxygen species; IDA:FlyBase.::GO:0042742; P:defense response to bacterium; IMP:FlyBase.::GO:0050832; P:defense response to fungus; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IDA:UniProtKB.::GO:0006955; P:immune response; IMP:FlyBase.::GO:0045793; P:positive regulation of cell size; IMP:FlyBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:FlyBase.::GO:0001934; P:positive regulation of protein phosphorylation; IGI:FlyBase.::GO:0048082; P:regulation of adult chitin-containing cuticle pigmentation; IGI:FlyBase.::GO:0030510; P:regulation of BMP signaling pathway; IDA:UniProtKB.::GO:0045088; P:regulation of innate immune response; IDA:UniProtKB.::GO:0009408; P:response to heat; IMP:FlyBase.::GO:0042542; P:response to hydrogen peroxide; IMP:FlyBase.::GO:0009651; P:response to salt stress; IMP:FlyBase.::GO:0042594; P:response to starvation; IMP:FlyBase.
84Q9WV60    420   GSK3B_MOUSE Glycogen synthase kinase-3 beta O...2262e-30     124     35     51GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI.::GO:0043198; C:dendritic shaft; IDA:MGI.::GO:0030426; C:growth cone; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0030529; C:ribonucleoprotein complex; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008013; F:beta-catenin binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:MGI.
GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0007409; P:axonogenesis; IGI:MGI.::GO:0044337; P:canonical Wnt receptor signaling pathway involved in positive regulation of apoptotic process; IMP:BHF-UCL.::GO:0016477; P:cell migration; IGI:MGI.::GO:0008283; P:cell proliferation; TAS:MGI.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0006983; P:ER overload response; IDA:MGI.::GO:0045444; P:fat cell differentiation; IDA:MGI.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0044027; P:hypermethylation of CpG island; IMP:BHF-UCL.::GO:0007520; P:myoblast fusion; IDA:MGI.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; ISS:UniProtKB.::GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:MGI.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:MGI.::GO:0032092; P:positive regulation of protein binding; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0006611; P:protein export from nucleus; IDA:MGI.::GO:0035372; P:protein localization to microtubule; IGI:MGI.::GO:0000320; P:re-entry into mitotic cell cycle; IDA:MGI.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:BHF-UCL.::GO:0032886; P:regulation of microtubule-based process; IDA:UniProtKB.
85P49841    420   GSK3B_HUMAN Glycogen synthase kinase-3 beta O...2262e-30     124     35     51GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:BHF-UCL.::GO:0030877; C:beta-catenin destruction complex; IDA:UniProtKB.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.::GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0002039; F:p53 binding; IDA:MGI.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0060070; P:canonical Wnt receptor signaling pathway; IC:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0001837; P:epithelial to mesenchymal transition; IMP:UniProtKB.::GO:0006983; P:ER overload response; IDA:MGI.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0005977; P:glycogen metabolic process; IDA:BHF-UCL.::GO:0021766; P:hippocampus development; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; TAS:UniProtKB.::GO:2000466; P:negative regulation of glycogen (starch) synthase activity; TAS:UniProtKB.::GO:0045719; P:negative regulation of glycogen biosynthetic process; TAS:UniProtKB.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; IMP:UniProtKB.::GO:0032091; P:negative regulation of protein binding; IDA:BHF-UCL.::GO:0031333; P:negative regulation of protein complex assembly; IMP:BHF-UCL.::GO:2000077; P:negative regulation of type B pancreatic cell development; TAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; IC:BHF-UCL.::GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.::GO:0046827; P:positive regulation of protein export from nucleus; IDA:MGI.::GO:0032855; P:positive regulation of Rac GTPase activity; IMP:BHF-UCL.::GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.::GO:0071109; P:superior temporal gyrus development; IMP:BHF-UCL.
86Q8L4P8    303   CKB11_ORYSJ Cyclin-dependent kinase B1-1 OS=O...3352e-30     122     26     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
87Q5YJC2    420   GSK3B_SPECI Glycogen synthase kinase-3 beta O...3312e-30     124     29     46GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; ISS:UniProtKB.::GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0032886; P:regulation of microtubule-based process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
88Q00526    305   CDK3_HUMAN Cyclin-dependent kinase 3 OS=Homo ...3333e-30     122     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:ProtInc.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0045023; P:G0 to G1 transition; TAS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
89Q8LF80    313   CKB21_ARATH Cyclin-dependent kinase B2-1 OS=A...3463e-30     122     28     47GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:TAIR.::GO:0016572; P:histone phosphorylation; IDA:TAIR.::GO:0009755; P:hormone-mediated signaling pathway; IEP:TAIR.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:TAIR.::GO:0009934; P:regulation of meristem structural organization; IMP:TAIR.
90P18265    483   GSK3A_RAT Glycogen synthase kinase-3 alpha OS...2263e-30     124     34     51GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
91P93101    294   CDC2_CHERU Cell division control protein 2 ho...3333e-30     121     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
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