Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL035C
Length:
372
Number of sequences:
5887
Description:
YIL035C CKA1 SGDID:S000001297, Chr IX from 288908-287790, Genome Release 64-1-1, reverse complement, Verified ORF, "Alpha catalytic subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
451Q54DF2    1060   MRKA_DICDI Probable serine/threonine-protein ...2444e-19     92.8     26     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
452Q9WTU6    423   MK09_MOUSE Mitogen-activated protein kinase 9...2604e-19     91.7     25     48GO:0044445; C:cytosolic part; ISS:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IC:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; ISS:UniProtKB.
GO:0031558; P:induction of apoptosis in response to chemical stimulus; IGI:MGI.::GO:0046686; P:response to cadmium ion; IGI:MGI.
453Q10KY3    600   CAMK1_ORYSJ Calcium/calmodulin-dependent seri...3384e-19     92     23     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
454Q5SN53    569   MPK8_ORYSJ Mitogen-activated protein kinase 8...3395e-19     92     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
455O44514    474   PMK3_CAEEL Mitogen-activated protein kinase p...2015e-19     91.7     30     54GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0050807; P:regulation of synapse organization; IGI:WormBase.::GO:0006950; P:response to stress; IDA:UniProtKB.::GO:0071688; P:striated muscle myosin thick filament assembly; IMP:WormBase.
456A3LUB9    431   SSN3_PICST Serine/threonine-protein kinase SS...2655e-19     91.3     28     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
457Q54WE5    811   PRP4B_DICDI Serine/threonine-protein kinase p...3557e-19     92     24     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0008380; P:RNA splicing; ISS:dictyBase.
458P31152    587   MK04_HUMAN Mitogen-activated protein kinase 4...2268e-19     91.3     26     53GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; TAS:ProtInc.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
459P29294    1147   MYLK_RABIT Myosin light chain kinase, smooth ...3529e-19     91.7     24     42GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
460Q3MJK5    1484   CDK12_RAT Cyclin-dependent kinase 12 OS=Rattu...3471e-18     91.3     25     46GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IMP:UniProtKB.
461Q14AX6    1484   CDK12_MOUSE Cyclin-dependent kinase 12 OS=Mus...3471e-18     91.3     25     46GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:HGNC.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
462Q54D75    1397   Y2550_DICDI Probable cyclin-dependent serine/...3302e-18     90.9     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
463P11799    1906   MYLK_CHICK Myosin light chain kinase, smooth ...3522e-18     90.9     23     41GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
464D2H526    1491   CDK12_AILME Cyclin-dependent kinase 12 OS=Ail...3472e-18     90.5     25     45GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
465Q5VP69    501   MPK16_ORYSJ Mitogen-activated protein kinase ...3612e-18     89.7     23     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
466Q09437    719   YP62_CAEEL Putative serine/threonine-protein ...3492e-18     90.1     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.
467Q91Y86    384   MK08_MOUSE Mitogen-activated protein kinase 8...2503e-18     88.6     25     49GO:0005829; C:cytosol; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0031558; P:induction of apoptosis in response to chemical stimulus; IGI:MGI.::GO:0001503; P:ossification; IMP:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IMP:MGI.::GO:2000017; P:positive regulation of determination of dorsal identity; IDA:MGI.::GO:0046686; P:response to cadmium ion; IGI:MGI.
468Q75KK8    542   MPK14_ORYSJ Mitogen-activated protein kinase ...3394e-18     89     24     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
469Q6L5F7    582   MPK17_ORYSJ Mitogen-activated protein kinase ...3405e-18     89     23     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
470Q8SRF5    265   Y823_ENCCU Probable cell division protein kin...3086e-18     85.9     24     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
471Q53N72    498   MPK15_ORYSJ Mitogen-activated protein kinase ...3396e-18     88.6     24     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
472Q8SW92    308   KIN28_ENCCU Probable serine/threonine-protein...3476e-18     86.7     25     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
473Q09815    836   PPK5_SCHPO Serine/threonine-protein kinase pp...3416e-18     89     25     46GO:0032153; C:cell division site; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; NAS:PomBase.
474Q9NYV4    1490   CDK12_HUMAN Cyclin-dependent kinase 12 OS=Hom...3476e-18     89.4     25     45GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IMP:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:HGNC.::GO:0043405; P:regulation of MAP kinase activity; IMP:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
475Q9UQ88    783   CD11A_HUMAN Cyclin-dependent kinase 11A OS=Ho...2397e-18     89     26     51GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0007067; P:mitosis; NAS:UniProtKB.::GO:0001558; P:regulation of cell growth; IEP:UniProtKB.::GO:0050684; P:regulation of mRNA processing; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.
476P45983    427   MK08_HUMAN Mitogen-activated protein kinase 8...2507e-18     87.8     25     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0035033; F:histone deacetylase regulator activity; IMP:BHF-UCL.::GO:0004705; F:JUN kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0008633; P:activation of pro-apoptotic gene products; TAS:Reactome.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0032091; P:negative regulation of protein binding; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0090045; P:positive regulation of deacetylase activity; IMP:BHF-UCL.::GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.::GO:0032880; P:regulation of protein localization; IDA:BHF-UCL.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0009411; P:response to UV; IDA:MGI.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
477P34244    1518   HSL1_YEAST Probable serine/threonine-protein ...2387e-18     89     26     45GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005940; C:septin ring; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000078; P:cell shape checkpoint; TAS:SGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:SGD.::GO:0046777; P:protein autophosphorylation; IMP:SGD.::GO:0000135; P:septin checkpoint; IGI:SGD.
478Q2GYV9    512   SSN3_CHAGB Serine/threonine-protein kinase SS...2938e-18     88.2     26     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
479P49185    411   MK08_RAT Mitogen-activated protein kinase 8 O...2508e-18     87.4     25     49GO:0033267; C:axon part; IDA:RGD.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0032839; C:dendrite cytoplasm; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0043204; C:perikaryon; IDA:RGD.::GO:0031982; C:vesicle; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004705; F:JUN kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:RGD.
GO:0006954; P:inflammatory response; IDA:RGD.::GO:0043066; P:negative regulation of apoptotic process; IDA:RGD.::GO:0031175; P:neuron projection development; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; IEP:RGD.::GO:0030335; P:positive regulation of cell migration; IDA:RGD.::GO:0045740; P:positive regulation of DNA replication; IMP:RGD.::GO:0031116; P:positive regulation of microtubule polymerization; IMP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IDA:RGD.::GO:0009408; P:response to heat; IDA:RGD.::GO:0042542; P:response to hydrogen peroxide; IDA:RGD.::GO:0006970; P:response to osmotic stress; IDA:RGD.::GO:0048545; P:response to steroid hormone stimulus; IEP:RGD.
480Q5ZCI1    611   MPK10_ORYSJ Mitogen-activated protein kinase ...3551e-17     88.2     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
481P49187    464   MK10_RAT Mitogen-activated protein kinase 10 ...2641e-17     87.4     26     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0004705; F:JUN kinase activity; ISS:UniProtKB.
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