rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q9UL51 | 889 | HCN2_HUMAN Potassium/sodium hyperpolarization... | 99 | 0.0003 | 47 | 29 | 46 | GO:0008076; C:voltage-gated potassium channel complex; TAS:ProtInc. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | GO:0006936; P:muscle contraction; TAS:ProtInc.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 62 | P86244 | 167 | KAP0_MESAU cAMP-dependent protein kinase type... | 150 | 0.0004 | 44.3 | 25 | 44 | GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro. | 63 | Q9TV66 | 1175 | HCN4_RABIT Potassium/sodium hyperpolarization... | 99 | 0.0001 | 48.1 | 29 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | | 64 | Q9JKA7 | 1198 | HCN4_RAT Potassium/sodium hyperpolarization-a... | 99 | 0.0001 | 47.8 | 29 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043195; C:terminal button; IDA:RGD. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:RGD.::GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | GO:0050804; P:regulation of synaptic transmission; TAS:RGD. | 65 | Q9Y3Q4 | 1203 | HCN4_HUMAN Potassium/sodium hyperpolarization... | 99 | 0.0002 | 47.8 | 29 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | GO:0008015; P:blood circulation; NAS:ProtInc.::GO:0006936; P:muscle contraction; TAS:ProtInc.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 66 | Q9EQZ6 | 1011 | RPGF4_MOUSE Rap guanine nucleotide exchange f... | 83 | 0.038 | 40 | 29 | 53 | GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro.::GO:0005829; C:cytosol; IDA:MGI. | | | | | | | | | | GO:0030552; F:cAMP binding; IDA:UniProtKB.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0017016; F:Ras GTPase binding; IPI:UniProtKB.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0017156; P:calcium ion-dependent exocytosis; IDA:MGI.::GO:0019933; P:cAMP-mediated signaling; IDA:MGI.::GO:0030073; P:insulin secretion; IDA:MGI.::GO:0017157; P:regulation of exocytosis; IDA:MGI.::GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 67 | O70507 | 1186 | HCN4_MOUSE Potassium/sodium hyperpolarization... | 99 | 0.0002 | 47.8 | 29 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | | 68 | Q2K5E1 | 355 | CNGK1_RHIEC Cyclic nucleotide-gated potassium... | 105 | 0.000003 | 52.8 | 30 | 52 | GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | | 69 | Q8WZA2 | 1011 | RPGF4_HUMAN Rap guanine nucleotide exchange f... | 83 | 0.039 | 40 | 29 | 53 | GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro.::GO:0005624; C:membrane fraction; TAS:ProtInc. | | | | | | | | | | GO:0030552; F:cAMP binding; ISS:UniProtKB.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0017016; F:Ras GTPase binding; ISS:UniProtKB.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 70 | Q9JKB0 | 910 | HCN1_RAT Potassium/sodium hyperpolarization-a... | 99 | 0.004 | 43.5 | 27 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | | 71 | Q9MZS1 | 822 | HCN1_RABIT Potassium/sodium hyperpolarization... | 99 | 0.004 | 43.1 | 27 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | | 72 | P34578 | 1038 | RPGF1_CAEEL Rap guanine nucleotide exchange f... | 101 | 0.0000003 | 56.6 | 33 | 59 | GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro. | | | | | | | | | | GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 73 | O88704 | 910 | HCN1_MOUSE Potassium/sodium hyperpolarization... | 99 | 0.004 | 43.1 | 27 | 45 | GO:0030424; C:axon; IDA:MGI.::GO:0030425; C:dendrite; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | GO:0045176; P:apical protein localization; IMP:MGI.::GO:0046549; P:retinal cone cell development; IMP:MGI. | 74 | O60741 | 890 | HCN1_HUMAN Potassium/sodium hyperpolarization... | 99 | 0.004 | 43.1 | 27 | 45 | GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | GO:0007268; P:synaptic transmission; TAS:Reactome. | 75 | Q8VCC8 | 918 | RPGF3_MOUSE Rap guanine nucleotide exchange f... | 96 | 0.000003 | 53.1 | 30 | 54 | GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI. | | | | | | | | | | GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 76 | Q9Z1C8 | 926 | RPGF3_RAT Rap guanine nucleotide exchange fac... | 96 | 0.000004 | 52.8 | 30 | 53 | GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 77 | O95398 | 923 | RPGF3_HUMAN Rap guanine nucleotide exchange f... | 96 | 0.000001 | 54.3 | 31 | 53 | GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:ProtInc. | | | | | | | | | | GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 78 | Q5BK26 | 1349 | PLPL7_RAT Patatin-like phospholipase domain-c... | 200 | 0.00000002 | 60.1 | 26 | 47 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004091; F:carboxylesterase activity; IMP:RGD. | | | | | | | | | | GO:0006629; P:lipid metabolic process; IEA:InterPro. | 79 | Q98GN8 | 355 | CNGK1_RHILO Cyclic nucleotide-gated potassium... | 105 | 0.00003 | 49.7 | 28 | 50 | GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | | 80 | A2AJ88 | 1352 | PLPL7_MOUSE Patatin-like phospholipase domain... | 200 | 0.00000004 | 59.3 | 27 | 46 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006629; P:lipid metabolic process; IEA:InterPro. | 81 | Q10898 | 504 | Y104_MYCTU Uncharacterized protein Rv0104/MT0... | 62 | 0.0005 | 45.8 | 37 | 63 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 82 | Q9P1Z3 | 774 | HCN3_HUMAN Potassium/sodium hyperpolarization... | 99 | 0.025 | 40.8 | 25 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | GO:0007268; P:synaptic transmission; TAS:Reactome. | 83 | Q9JKA8 | 780 | HCN3_RAT Potassium/sodium hyperpolarization-a... | 99 | 0.024 | 40.8 | 25 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | | 84 | O88705 | 779 | HCN3_MOUSE Potassium/sodium hyperpolarization... | 99 | 0.025 | 40.4 | 25 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | | 85 | Q6ZV29 | 1317 | PLPL7_HUMAN Patatin-like phospholipase domain... | 198 | 0.0000006 | 55.5 | 26 | 44 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006629; P:lipid metabolic process; IEA:InterPro. | 86 | Q5RDS0 | 1365 | PLPL6_PONAB Neuropathy target esterase OS=Pon... | 87 | 5.5 | 33.1 | 28 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004622; F:lysophospholipase activity; IEA:EC. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro. | 87 | Q8IY17 | 1366 | PLPL6_HUMAN Neuropathy target esterase OS=Hom... | 87 | 5.7 | 33.1 | 28 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004622; F:lysophospholipase activity; IEA:EC. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro. | 88 | Q3TRM4 | 1355 | PLPL6_MOUSE Neuropathy target esterase OS=Mus... | 87 | 4.9 | 33.5 | 28 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004622; F:lysophospholipase activity; IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:MGI.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro. | 89 | Q02006 | 412 | Y4233_RHOPA Putative potassium channel protei... | 102 | 0.007 | 42 | 25 | 48 | GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | | 90 | Q653P0 | 858 | KOR1_ORYSJ Potassium channel KOR1 OS=Oryza sa... | 95 | 0.005 | 42.7 | 33 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 91 | P63402 | 330 | Y2593_MYCBO Uncharacterized ABC transporter A... | 102 | 0.024 | 40 | 25 | 44 | GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. |