Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL030C
Length:
1319
Number of sequences:
5887
Description:
YIL030C SSM4 SGDID:S000001292, Chr IX from 300009-296050, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-protein ligase involved in ER-associated protein degradation; located in the ER/nuclear envelope; ssm4 mutation suppresses mRNA instability caused by an rna14 mutation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q9P0N8    246   MARH2_HUMAN E3 ubiquitin-protein ligase MARCH...640.00005     50.1     38     52GO:0031410; C:cytoplasmic vesicle; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
32A6NNE9    402   MARHB_HUMAN E3 ubiquitin-protein ligase MARCH...1440.00007     50.4     28     44GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
33Q5I0I2    246   MARH2_RAT E3 ubiquitin-protein ligase MARCH2 ...640.00008     49.3     38     53GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
34Q32L65    245   MARH2_BOVIN E3 ubiquitin-protein ligase MARCH...640.0001     48.9     36     50GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
35Q99M02    246   MARH2_MOUSE E3 ubiquitin-protein ligase MARCH...560.0002     48.1     38     55GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
36Q5XIV2    790   MARHA_RAT Probable E3 ubiquitin-protein ligas...600.0002     49.3     37     60
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
37Q997C2    206   LAP_MYXVL E3 ubiquitin-protein ligase LAP OS=...870.0004     46.6     34     49GO:0044174; C:host cell endosome; IEA:UniProtKB-KW.::GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.
38Q28EX7    246   MARH2_XENTR E3 ubiquitin-protein ligase MARCH...590.0005     47     34     51GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
39Q5PQ35    246   MARH2_XENLA E3 ubiquitin-protein ligase MARCH...590.0005     47     34     51GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
40Q6NYK8    289   MARH5_DANRE E3 ubiquitin-protein ligase MARCH...720.002     45.4     35     44GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090344; P:negative regulation of cell aging; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0090140; P:regulation of mitochondrial fission; ISS:UniProtKB.
41Q1LVZ2    249   MARH2_DANRE E3 ubiquitin-protein ligase MARCH...580.003     44.3     33     50GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
42Q5ZJ41    281   MARH5_CHICK E3 ubiquitin-protein ligase MARCH...1230.005     44.3     27     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090344; P:negative regulation of cell aging; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
43Q6GM44    283   MARH5_XENLA E3 ubiquitin-protein ligase MARCH...590.005     44.3     36     51GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090344; P:negative regulation of cell aging; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0090140; P:regulation of mitochondrial fission; ISS:UniProtKB.
44Q3KNM2    278   MARH5_MOUSE E3 ubiquitin-protein ligase MARCH...1230.005     44.3     27     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090344; P:negative regulation of cell aging; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
45Q9NX47    278   MARH5_HUMAN E3 ubiquitin-protein ligase MARCH...1230.005     44.3     27     45GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IDA:UniProtKB.
GO:0051020; F:GTPase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090344; P:negative regulation of cell aging; IMP:UniProtKB.::GO:0090141; P:positive regulation of mitochondrial fission; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070585; P:protein localization in mitochondrion; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
46Q0X0A5    278   MARH5_CHLAE E3 ubiquitin-protein ligase MARCH...1230.005     44.3     27     45GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090344; P:negative regulation of cell aging; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0090140; P:regulation of mitochondrial fission; ISS:UniProtKB.
47Q3ZC24    278   MARH5_BOVIN E3 ubiquitin-protein ligase MARCH...1230.005     44.3     27     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090344; P:negative regulation of cell aging; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
48Q9Q8T2    201   LAP_RFVKA E3 ubiquitin-protein ligase LAP OS=...500.045     40.4     40     50GO:0044174; C:host cell endosome; IEA:UniProtKB-KW.::GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.
49Q15118    436   PDK1_HUMAN [Pyruvate dehydrogenase [lipoamide...1260.094     40.4     23     43GO:0005759; C:mitochondrial matrix; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; TAS:ProtInc.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006006; P:glucose metabolic process; TAS:ProtInc.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
50P27426    285   VIE1_BHV4D Probable E3 ubiquitin-protein liga...890.096     40     29     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
51Q8BFP9    434   PDK1_MOUSE [Pyruvate dehydrogenase [lipoamide...1260.12     40     23     42GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IEA:EC.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
52Q63065    434   PDK1_RAT [Pyruvate dehydrogenase [lipoamide]]...1260.13     40     23     42GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0045254; C:pyruvate dehydrogenase complex; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IDA:RGD.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0007166; P:cell surface receptor signaling pathway; IMP:RGD.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0018106; P:peptidyl-histidine phosphorylation; IEA:InterPro.
53P90489    256   MIR2_HHV8P E3 ubiquitin-protein ligase MIR2 O...490.18     38.9     37     49GO:0044165; C:host cell endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.
54Q18DN4    9159   HMU_HALWD Halomucin OS=Haloquadratum walsbyi ...1760.63     38.5     24     40GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030246; F:carbohydrate binding; IEA:InterPro.::GO:0004180; F:carboxypeptidase activity; IEA:InterPro.
GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
55O23693    573   MLO4_ARATH MLO-like protein 4 OS=Arabidopsis ...1293.4     35.8     25     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0008219; P:cell death; IEA:InterPro.::GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0009607; P:response to biotic stimulus; IEA:UniProtKB-KW.
56P90495    333   MIR1_HHV8P E3 ubiquitin-protein ligase MIR1 O...643.7     35     33     45GO:0044165; C:host cell endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.
57Q18G63    279   RS2_HALWD 30S ribosomal protein S2P OS=Haloqu...665.5     34.7     33     55GO:0015935; C:small ribosomal subunit; IEA:InterPro.
GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
58Q91T40    162   LAP_LSDV E3 ubiquitin-protein ligase LAP OS=L...566.8     33.5     30     48GO:0044174; C:host cell endosome; IEA:UniProtKB-KW.::GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.
59Q6TV02    156   LAP_YMTV5 E3 ubiquitin-protein ligase LAP OS=...1039.4     33.1     28     40GO:0044174; C:host cell endosome; IEA:UniProtKB-KW.::GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.
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