Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL030C
Length:
1319
Number of sequences:
5887
Description:
YIL030C SSM4 SGDID:S000001292, Chr IX from 300009-296050, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-protein ligase involved in ER-associated protein degradation; located in the ER/nuclear envelope; ssm4 mutation suppresses mRNA instability caused by an rna14 mutation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40318    1319   DOA10_YEAST ERAD-associated E3 ubiquitin-prot...13190     2735     100     100GO:0000837; C:Doa10p ubiquitin ligase complex; IDA:SGD.::GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD.::GO:0005637; C:nuclear inner membrane; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; IMP:SGD.
2O60103    1242   DOA10_SCHPO ERAD-associated E3 ubiquitin-prot...1272e-19     99     35     54GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:PomBase.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; ISS:PomBase.
3O60337    910   MARH6_HUMAN E3 ubiquitin-protein ligase MARCH...860.0000008     57.4     30     63GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.
GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
4Q6ZQ89    909   MARH6_MOUSE E3 ubiquitin-protein ligase MARCH...860.0000008     57.4     30     63GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
5Q5R9W1    910   MARH6_PONAB E3 ubiquitin-protein ligase MARCH...860.0000007     57.8     30     63GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
6Q6NZQ8    289   MARH1_MOUSE E3 ubiquitin-protein ligase MARCH...630.00000003     60.1     35     59GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IDA:UniProtKB.::GO:0005765; C:lysosomal membrane; IDA:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0032588; C:trans-Golgi network membrane; IDA:UniProtKB.
GO:0042287; F:MHC protein binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0002495; P:antigen processing and presentation of peptide antigen via MHC class II; IMP:UniProtKB.::GO:0006955; P:immune response; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
7Q8TCQ1    289   MARH1_HUMAN E3 ubiquitin-protein ligase MARCH...570.0000002     57.8     37     61GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IDA:UniProtKB.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0032588; C:trans-Golgi network membrane; ISS:UniProtKB.
GO:0042287; F:MHC protein binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0002495; P:antigen processing and presentation of peptide antigen via MHC class II; IDA:UniProtKB.::GO:0006955; P:immune response; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
8Q9DBD2    286   MARH8_MOUSE E3 ubiquitin-protein ligase MARCH...630.0000005     56.6     33     56GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0042289; F:MHC class II protein binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0002495; P:antigen processing and presentation of peptide antigen via MHC class II; IDA:UniProtKB.::GO:0045347; P:negative regulation of MHC class II biosynthetic process; IDA:BHF-UCL.
9Q5T0T0    291   MARH8_HUMAN E3 ubiquitin-protein ligase MARCH...630.0000005     56.6     33     56GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
10Q28IK8    264   MARH8_XENTR E3 ubiquitin-protein ligase MARCH...630.000001     55.1     32     56GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
11Q5XI50    692   MARH7_RAT E3 ubiquitin-protein ligase MARCH7 ...650.000001     56.6     37     57
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
12Q0VD59    289   MARH8_BOVIN E3 ubiquitin-protein ligase MARCH...570.000002     54.7     35     60GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
13Q9P2E8    410   MARH4_HUMAN E3 ubiquitin-protein ligase MARCH...1150.000003     55.1     29     47GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
14Q0IH10    252   MARH3_XENLA E3 ubiquitin-protein ligase MARCH...800.000003     53.9     33     51GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
15Q9WV66    693   MARH7_MOUSE E3 ubiquitin-protein ligase MARCH...620.000003     55.5     37     58
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
16Q0P496    421   MARH4_DANRE E3 ubiquitin-protein ligase MARCH...1130.000003     54.7     29     47GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
17Q68FA7    251   MARH3_XENTR E3 ubiquitin-protein ligase MARCH...700.000006     52.8     34     54GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
18Q5R9W2    707   MARH7_PONAB E3 ubiquitin-protein ligase MARCH...620.000006     54.3     35     58
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
19Q9H992    704   MARH7_HUMAN E3 ubiquitin-protein ligase MARCH...620.000007     54.3     35     58
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
20Q80TE3    409   MARH4_MOUSE E3 ubiquitin-protein ligase MARCH...1150.000007     53.9     29     46GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
21Q5XH39    264   MARH8_XENLA E3 ubiquitin-protein ligase MARCH...630.00001     52     32     56GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
22Q86YJ5    346   MARH9_HUMAN E3 ubiquitin-protein ligase MARCH...1130.00003     51.6     27     47GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
23Q3TZ87    348   MARH9_MOUSE E3 ubiquitin-protein ligase MARCH...1130.00003     51.6     27     47GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
24Q8BRX9    218   MARH3_MOUSE E3 ubiquitin-protein ligase MARCH...700.00003     50.1     36     51GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
25Q8NA82    808   MARHA_HUMAN Probable E3 ubiquitin-protein lig...560.00004     51.6     38     59
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
26A6P320    398   MARHB_RAT E3 ubiquitin-protein ligase MARCH11...1440.00004     51.2     26     42GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
27Q8CBH7    400   MARHB_MOUSE E3 ubiquitin-protein ligase MARCH...1440.00004     51.2     26     42GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
28Q5XIE5    253   MARH3_RAT E3 ubiquitin-protein ligase MARCH3 ...700.00005     50.1     36     51GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
29Q86UD3    253   MARH3_HUMAN E3 ubiquitin-protein ligase MARCH...700.00005     50.1     36     51GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; IDA:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
30A0JN69    253   MARH3_BOVIN E3 ubiquitin-protein ligase MARCH...700.00005     50.1     36     51GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
31Q9P0N8    246   MARH2_HUMAN E3 ubiquitin-protein ligase MARCH...640.00005     50.1     38     52GO:0031410; C:cytoplasmic vesicle; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
records
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