rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P40318 | 1319 | DOA10_YEAST ERAD-associated E3 ubiquitin-prot... | 1319 | 0 | 2735 | 100 | 100 | GO:0000837; C:Doa10p ubiquitin ligase complex; IDA:SGD.::GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD.::GO:0005637; C:nuclear inner membrane; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; IMP:SGD. | 2 | O60103 | 1242 | DOA10_SCHPO ERAD-associated E3 ubiquitin-prot... | 127 | 2e-19 | 99 | 35 | 54 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:PomBase. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030433; P:ER-associated protein catabolic process; ISS:PomBase. | 3 | O60337 | 910 | MARH6_HUMAN E3 ubiquitin-protein ligase MARCH... | 86 | 0.0000008 | 57.4 | 30 | 63 | GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB. | | | | | | | | | | GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB. | 4 | Q6ZQ89 | 909 | MARH6_MOUSE E3 ubiquitin-protein ligase MARCH... | 86 | 0.0000008 | 57.4 | 30 | 63 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB. | 5 | Q5R9W1 | 910 | MARH6_PONAB E3 ubiquitin-protein ligase MARCH... | 86 | 0.0000007 | 57.8 | 30 | 63 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB. | 6 | Q6NZQ8 | 289 | MARH1_MOUSE E3 ubiquitin-protein ligase MARCH... | 63 | 0.00000003 | 60.1 | 35 | 59 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IDA:UniProtKB.::GO:0005765; C:lysosomal membrane; IDA:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0032588; C:trans-Golgi network membrane; IDA:UniProtKB. | | | | | | | | | | GO:0042287; F:MHC protein binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0002495; P:antigen processing and presentation of peptide antigen via MHC class II; IMP:UniProtKB.::GO:0006955; P:immune response; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 7 | Q8TCQ1 | 289 | MARH1_HUMAN E3 ubiquitin-protein ligase MARCH... | 57 | 0.0000002 | 57.8 | 37 | 61 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031902; C:late endosome membrane; IDA:UniProtKB.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0032588; C:trans-Golgi network membrane; ISS:UniProtKB. | | | | | | | | | | GO:0042287; F:MHC protein binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0002495; P:antigen processing and presentation of peptide antigen via MHC class II; IDA:UniProtKB.::GO:0006955; P:immune response; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 8 | Q9DBD2 | 286 | MARH8_MOUSE E3 ubiquitin-protein ligase MARCH... | 63 | 0.0000005 | 56.6 | 33 | 56 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042289; F:MHC class II protein binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0002495; P:antigen processing and presentation of peptide antigen via MHC class II; IDA:UniProtKB.::GO:0045347; P:negative regulation of MHC class II biosynthetic process; IDA:BHF-UCL. | 9 | Q5T0T0 | 291 | MARH8_HUMAN E3 ubiquitin-protein ligase MARCH... | 63 | 0.0000005 | 56.6 | 33 | 56 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 10 | Q28IK8 | 264 | MARH8_XENTR E3 ubiquitin-protein ligase MARCH... | 63 | 0.000001 | 55.1 | 32 | 56 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 11 | Q5XI50 | 692 | MARH7_RAT E3 ubiquitin-protein ligase MARCH7 ... | 65 | 0.000001 | 56.6 | 37 | 57 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 12 | Q0VD59 | 289 | MARH8_BOVIN E3 ubiquitin-protein ligase MARCH... | 57 | 0.000002 | 54.7 | 35 | 60 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 13 | Q9P2E8 | 410 | MARH4_HUMAN E3 ubiquitin-protein ligase MARCH... | 115 | 0.000003 | 55.1 | 29 | 47 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 14 | Q0IH10 | 252 | MARH3_XENLA E3 ubiquitin-protein ligase MARCH... | 80 | 0.000003 | 53.9 | 33 | 51 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 15 | Q9WV66 | 693 | MARH7_MOUSE E3 ubiquitin-protein ligase MARCH... | 62 | 0.000003 | 55.5 | 37 | 58 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 16 | Q0P496 | 421 | MARH4_DANRE E3 ubiquitin-protein ligase MARCH... | 113 | 0.000003 | 54.7 | 29 | 47 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 17 | Q68FA7 | 251 | MARH3_XENTR E3 ubiquitin-protein ligase MARCH... | 70 | 0.000006 | 52.8 | 34 | 54 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 18 | Q5R9W2 | 707 | MARH7_PONAB E3 ubiquitin-protein ligase MARCH... | 62 | 0.000006 | 54.3 | 35 | 58 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 19 | Q9H992 | 704 | MARH7_HUMAN E3 ubiquitin-protein ligase MARCH... | 62 | 0.000007 | 54.3 | 35 | 58 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 20 | Q80TE3 | 409 | MARH4_MOUSE E3 ubiquitin-protein ligase MARCH... | 115 | 0.000007 | 53.9 | 29 | 46 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 21 | Q5XH39 | 264 | MARH8_XENLA E3 ubiquitin-protein ligase MARCH... | 63 | 0.00001 | 52 | 32 | 56 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 22 | Q86YJ5 | 346 | MARH9_HUMAN E3 ubiquitin-protein ligase MARCH... | 113 | 0.00003 | 51.6 | 27 | 47 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 23 | Q3TZ87 | 348 | MARH9_MOUSE E3 ubiquitin-protein ligase MARCH... | 113 | 0.00003 | 51.6 | 27 | 47 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 24 | Q8BRX9 | 218 | MARH3_MOUSE E3 ubiquitin-protein ligase MARCH... | 70 | 0.00003 | 50.1 | 36 | 51 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 25 | Q8NA82 | 808 | MARHA_HUMAN Probable E3 ubiquitin-protein lig... | 56 | 0.00004 | 51.6 | 38 | 59 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 26 | A6P320 | 398 | MARHB_RAT E3 ubiquitin-protein ligase MARCH11... | 144 | 0.00004 | 51.2 | 26 | 42 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 27 | Q8CBH7 | 400 | MARHB_MOUSE E3 ubiquitin-protein ligase MARCH... | 144 | 0.00004 | 51.2 | 26 | 42 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 28 | Q5XIE5 | 253 | MARH3_RAT E3 ubiquitin-protein ligase MARCH3 ... | 70 | 0.00005 | 50.1 | 36 | 51 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 29 | Q86UD3 | 253 | MARH3_HUMAN E3 ubiquitin-protein ligase MARCH... | 70 | 0.00005 | 50.1 | 36 | 51 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; IDA:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 30 | A0JN69 | 253 | MARH3_BOVIN E3 ubiquitin-protein ligase MARCH... | 70 | 0.00005 | 50.1 | 36 | 51 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 31 | Q9P0N8 | 246 | MARH2_HUMAN E3 ubiquitin-protein ligase MARCH... | 64 | 0.00005 | 50.1 | 38 | 52 | GO:0031410; C:cytoplasmic vesicle; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. |