rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q29432 | 380 | PAG1_BOVIN Pregnancy-associated glycoprotein ... | 368 | 0.000000000000003 | 81.3 | 26 | 42 | GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 92 | P18276 | 381 | CHYM_SHEEP Chymosin OS=Ovis aries (Sheep). GN... | 371 | 0.000000000000003 | 81.3 | 27 | 44 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 93 | P24268 | 407 | CATD_RAT Cathepsin D OS=Rattus norvegicus (Ra... | 394 | 0.000000000000005 | 80.9 | 25 | 40 | GO:0005764; C:lysosome; IDA:RGD.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0042277; F:peptide binding; IDA:RGD. | | | | | | | | | | GO:0006914; P:autophagy; IEP:RGD.::GO:0006508; P:proteolysis; IDA:RGD. | 94 | Q28389 | 388 | PAG_HORSE Pregnancy-associated glycoprotein O... | 374 | 0.000000000000006 | 80.5 | 25 | 44 | GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 95 | P43159 | 396 | CATE_RABIT Cathepsin E OS=Oryctolagus cunicul... | 369 | 0.000000000000006 | 80.5 | 24 | 42 | GO:0005768; C:endosome; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 96 | C5PEI9 | 443 | PEPA_COCP7 Aspartic protease PEP3 OS=Coccidio... | 368 | 0.000000000000006 | 80.9 | 27 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 97 | Q29078 | 389 | PAG1_PIG Pregnancy-associated glycoprotein 1 ... | 369 | 0.000000000000008 | 80.1 | 24 | 41 | GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 98 | Q4WNV0 | 474 | CTSD_ASPFU Aspartic-type endopeptidase ctsD O... | 376 | 0.000000000000008 | 80.9 | 24 | 43 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 99 | O59774 | 521 | YPS1_SCHPO Aspartic proteinase yapsin-1 OS=Sc... | 410 | 0.000000000000008 | 80.9 | 25 | 45 | GO:0009986; C:cell surface; NAS:PomBase.::GO:0005618; C:cell wall; TAS:PomBase.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 100 | P07339 | 412 | CATD_HUMAN Cathepsin D OS=Homo sapiens (Human... | 406 | 0.000000000000009 | 80.1 | 24 | 40 | GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; TAS:ProtInc. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 101 | D4D8U6 | 509 | CTSD_TRIVH Probable aspartic-type endopeptida... | 375 | 0.00000000000001 | 80.1 | 25 | 42 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 102 | D4AZK1 | 509 | CTSD_ARTBC Probable aspartic-type endopeptida... | 378 | 0.00000000000002 | 79.7 | 25 | 42 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 103 | P06281 | 402 | RENI1_MOUSE Renin-1 OS=Mus musculus (Mouse). ... | 374 | 0.00000000000003 | 78.2 | 25 | 42 | GO:0005615; C:extracellular space; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0002003; P:angiotensin maturation; IMP:MGI.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0042756; P:drinking behavior; IMP:MGI.::GO:0009755; P:hormone-mediated signaling pathway; IDA:MGI.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0001823; P:mesonephros development; IEP:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0002018; P:renin-angiotensin regulation of aldosterone production; IDA:MGI. | 104 | P10977 | 419 | CARPV_CANAX Vacuolar aspartic protease OS=Can... | 370 | 0.00000000000004 | 78.2 | 24 | 41 | GO:0005773; C:vacuole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 105 | Q29079 | 420 | PAG2_PIG Pregnancy-associated glycoprotein 2 ... | 432 | 0.00000000000005 | 78.2 | 23 | 39 | GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 106 | P00799 | 430 | CARP_RHIMI Mucorpepsin OS=Rhizomucor miehei. ... | 389 | 0.00000000000006 | 77.8 | 24 | 42 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 107 | P06026 | 393 | CARP_RHICH Rhizopuspepsin OS=Rhizopus chinens... | 364 | 0.00000000000006 | 77.4 | 26 | 44 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 108 | O42630 | 398 | CARP_ASPFU Vacuolar protease A OS=A1100) (Asp... | 386 | 0.00000000000008 | 77 | 25 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 109 | O13340 | 425 | CARP_PODAS Podosporapepsin OS=Podospora anser... | 368 | 0.00000000000009 | 77 | 24 | 40 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 110 | P00794 | 381 | CHYM_BOVIN Chymosin OS=Bos taurus (Bovine). G... | 372 | 0.0000000000001 | 76.6 | 27 | 43 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 111 | P00796 | 401 | RENI2_MOUSE Renin-2 OS=Mus musculus (Mouse). ... | 374 | 0.0000000000002 | 75.9 | 26 | 42 | GO:0005615; C:extracellular space; IDA:MGI. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045777; P:positive regulation of blood pressure; IDA:MGI.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 112 | P00795 | 345 | CATD_PIG Cathepsin D OS=Sus scrofa (Pig). GN=... | 403 | 0.0000000000005 | 74.3 | 25 | 40 | GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 113 | O09043 | 419 | NAPSA_MOUSE Napsin-A OS=Mus musculus (Mouse).... | 392 | 0.0000000000006 | 74.7 | 25 | 41 | GO:0042599; C:lamellar body; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033619; P:membrane protein proteolysis; IMP:UniProtKB. | 114 | Q4WFS2 | 439 | Y1220_ASPFU Probable aspartic-type endopeptid... | 379 | 0.0000000000007 | 74.3 | 26 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 115 | P00798 | 323 | PENP_PENJA Penicillopepsin OS=Penicillium jan... | 369 | 0.0000000000008 | 73.2 | 27 | 43 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 116 | P32834 | 533 | SXA1_SCHPO Aspartic proteinase sxa1 OS=Schizo... | 423 | 0.000000000001 | 74.3 | 26 | 45 | GO:0009986; C:cell surface; TAS:PomBase.::GO:0005783; C:endoplasmic reticulum; IDA:PomBase.::GO:0005886; C:plasma membrane; IDA:PomBase. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; TAS:PomBase. | | | | | | | | | | GO:0000747; P:conjugation with cellular fusion; IMP:PomBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 117 | Q689Z7 | 391 | PEPC_MONDO Gastricsin OS=Monodelphis domestic... | 371 | 0.000000000002 | 72.8 | 22 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 118 | O01530 | 389 | ASP6_CAEEL Aspartic protease 6 OS=Caenorhabdi... | 374 | 0.000000000003 | 72 | 24 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008219; P:cell death; IMP:WormBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 119 | P08424 | 402 | RENI_RAT Renin OS=Rattus norvegicus (Rat). GN... | 374 | 0.000000000005 | 71.6 | 25 | 41 | GO:0044444; C:cytoplasmic part; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0005159; F:insulin-like growth factor receptor binding; IDA:RGD. | | | | | | | | | | GO:0002003; P:angiotensin maturation; IDA:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0051591; P:response to cAMP; IDA:RGD.::GO:0070305; P:response to cGMP; IDA:RGD.::GO:0042493; P:response to drug; IDA:RGD.::GO:0006950; P:response to stress; IDA:RGD. | 120 | P81214 | 395 | CARP_SYNRA Syncephapepsin OS=Syncephalastrum ... | 371 | 0.000000000005 | 71.6 | 26 | 41 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 121 | Q8SQ41 | 390 | PEPB_CANFA Pepsin B OS=Canis familiaris (Dog)... | 369 | 0.000000000007 | 71.2 | 24 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |