rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P40555 | 220 | PSMD9_YEAST Probable 26S proteasome regulator... | 220 | 3e-160 | 449 | 100 | 100 | GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0070682; P:proteasome regulatory particle assembly; IDA:SGD. | 2 | Q9WTV5 | 222 | PSMD9_RAT 26S proteasome non-ATPase regulator... | 199 | 8e-37 | 134 | 39 | 59 | GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0043425; F:bHLH transcription factor binding; IDA:BHF-UCL.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0003713; F:transcription coactivator activity; IDA:BHF-UCL. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:BHF-UCL.::GO:0046676; P:negative regulation of insulin secretion; IMP:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB. | 3 | Q3SZ19 | 221 | PSMD9_BOVIN 26S proteasome non-ATPase regulat... | 195 | 4e-35 | 129 | 37 | 60 | | | | | | | | | | | | | | | | | | | | | GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB. | 4 | O00233 | 223 | PSMD9_HUMAN 26S proteasome non-ATPase regulat... | 197 | 4e-34 | 127 | 37 | 57 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005838; C:proteasome regulatory particle; NAS:UniProtKB. | | | | | | | | | | GO:0043425; F:bHLH transcription factor binding; ISS:BHF-UCL.::GO:0003713; F:transcription coactivator activity; ISS:BHF-UCL. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0046676; P:negative regulation of insulin secretion; ISS:BHF-UCL.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0032024; P:positive regulation of insulin secretion; ISS:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:BHF-UCL.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070682; P:proteasome regulatory particle assembly; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 5 | Q9CR00 | 222 | PSMD9_MOUSE 26S proteasome non-ATPase regulat... | 196 | 1e-33 | 125 | 37 | 59 | GO:0005634; C:nucleus; ISS:BHF-UCL. | | | | | | | | | | GO:0043425; F:bHLH transcription factor binding; ISS:BHF-UCL.::GO:0003713; F:transcription coactivator activity; ISS:BHF-UCL. | | | | | | | | | | GO:0046676; P:negative regulation of insulin secretion; ISS:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; ISS:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:BHF-UCL.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB. | 6 | Q10920 | 197 | PSMD9_CAEEL Probable 26S proteasome non-ATPas... | 190 | 2e-21 | 92 | 31 | 55 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 7 | O94393 | 213 | PSMD9_SCHPO Probable 26S proteasome regulator... | 221 | 9e-16 | 76.6 | 27 | 46 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IC:PomBase.::GO:0070682; P:proteasome regulatory particle assembly; ISS:PomBase. | 8 | Q552Y8 | 262 | PSMD9_DICDI Probable 26S proteasome non-ATPas... | 236 | 0.00000000000001 | 73.6 | 26 | 43 | GO:0005838; C:proteasome regulatory particle; ISS:dictyBase. | | | | | | | | | | | | | | | | | | | | GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:dictyBase. | 9 | Q9RPP2 | 422 | EEP_ENTFA Probable protease eep OS=Enterococc... | 69 | 0.004 | 41.2 | 30 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 10 | Q9Z6T0 | 488 | DEGPL_CHLPN Probable periplasmic serine endop... | 91 | 0.007 | 40.8 | 30 | 56 | GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 11 | Q8WWI1 | 1683 | LMO7_HUMAN LIM domain only protein 7 OS=Homo ... | 66 | 0.051 | 38.1 | 33 | 59 | GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005634; C:nucleus; TAS:ProtInc.::GO:0000151; C:ubiquitin ligase complex; NAS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 12 | Q9CJL2 | 442 | Y1991_PASMU Putative zinc metalloprotease PM1... | 79 | 0.097 | 37 | 32 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 13 | O83609 | 450 | Y600_TREPA Putative zinc metalloprotease TP_0... | 72 | 0.16 | 36.2 | 29 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 14 | P72780 | 394 | HHOA_SYNY3 Putative serine protease HhoA OS=S... | 118 | 0.3 | 35.4 | 20 | 44 | GO:0030288; C:outer membrane-bounded periplasmic space; IDA:UniProtKB. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 15 | P44936 | 443 | Y918_HAEIN Putative zinc metalloprotease HI_0... | 79 | 0.47 | 35 | 27 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 16 | Q8SQG9 | 316 | NHRF2_RABIT Na(+)/H(+) exchange regulatory co... | 78 | 0.54 | 34.7 | 28 | 53 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008022; F:protein C-terminus binding; IPI:UniProtKB. | | | | | | | | | | | 17 | Q9PL97 | 497 | DEGPL_CHLMU Probable periplasmic serine endop... | 91 | 0.56 | 34.7 | 27 | 54 | GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 18 | Q9WZZ2 | 501 | Y890_THEMA Putative zinc metalloprotease TM_0... | 78 | 0.57 | 34.7 | 31 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 19 | A6YFB5 | 459 | HTRA1_XENLA Serine protease HTRA1 OS=Xenopus ... | 62 | 0.72 | 34.3 | 34 | 58 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro. | 20 | Q9S342 | 226 | RSEP_PHOLU Protease rseP OS=Photorhabdus lumi... | 67 | 0.77 | 33.9 | 27 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 21 | Q9JHL1 | 337 | NHRF2_MOUSE Na(+)/H(+) exchange regulatory co... | 42 | 0.87 | 33.9 | 31 | 57 | GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0019902; F:phosphatase binding; IPI:UniProtKB. | | | | | | | | | | GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase cascade; IGI:MGI. | 22 | Q15599 | 337 | NHRF2_HUMAN Na(+)/H(+) exchange regulatory co... | 42 | 0.93 | 33.9 | 31 | 57 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0019902; F:phosphatase binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0005102; F:receptor binding; IPI:UniProtKB. | | | | | | | | | | GO:0006461; P:protein complex assembly; TAS:ProtInc. | 23 | P26982 | 475 | DEGP_SALTY Periplasmic serine endoprotease De... | 159 | 1.1 | 33.9 | 25 | 45 | GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; ISS:UniProtKB.::GO:0006457; P:protein folding; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; ISS:UniProtKB.::GO:0009266; P:response to temperature stimulus; ISS:UniProtKB. | 24 | P39099 | 455 | DEGQ_ECOLI Periplasmic pH-dependent serine en... | 68 | 1.3 | 33.5 | 31 | 54 | GO:0042597; C:periplasmic space; IDA:UniProtKB. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0051603; P:proteolysis involved in cellular protein catabolic process; IDA:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 25 | Q6CWI4 | 1651 | HIR3_KLULA Histone transcription regulator 3 ... | 86 | 1.4 | 33.9 | 29 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 26 | O34358 | 449 | HTRA_BACSU Serine protease Do-like HtrA OS=Ba... | 60 | 1.5 | 33.5 | 35 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 27 | A4D2P6 | 1211 | GRD2I_HUMAN Delphilin OS=Homo sapiens (Human)... | 61 | 1.9 | 33.1 | 30 | 56 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 28 | P18584 | 497 | DEGPL_CHLTR Probable periplasmic serine endop... | 91 | 2.3 | 32.7 | 24 | 54 | GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 29 | A4IHA1 | 460 | HTRA1_XENTR Serine protease HTRA1 OS=Xenopus ... | 69 | 2.4 | 32.7 | 29 | 52 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro. | 30 | O61967 | 699 | LAP1_CAEEL Protein lap1 OS=Caenorhabditis ele... | 81 | 2.6 | 32.7 | 26 | 48 | GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0016323; C:basolateral plasma membrane; IDA:WormBase. | | | | | | | | | | | | | | | | | | | | GO:0030029; P:actin filament-based process; IMP:WormBase.::GO:0007155; P:cell adhesion; IMP:WormBase.::GO:0007043; P:cell-cell junction assembly; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007163; P:establishment or maintenance of cell polarity; IEP:UniProtKB.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0030728; P:ovulation; IMP:WormBase.::GO:0060465; P:pharynx development; IMP:WormBase.::GO:0015031; P:protein transport; IEP:UniProtKB.::GO:0045108; P:regulation of intermediate filament polymerization or depolymerization; IMP:UniProtKB. | 31 | Q0QWG9 | 1203 | GRD2I_MOUSE Delphilin OS=Mus musculus (Mouse)... | 61 | 3.7 | 32.3 | 28 | 56 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.::GO:0007216; P:G-protein coupled glutamate receptor signaling pathway; TAS:MGI.::GO:0060292; P:long term synaptic depression; IMP:MGI. |