Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL007C
Length:
220
Number of sequences:
5887
Description:
YIL007C NAS2 SGDID:S000001269, Chr IX from 343656-342994, Genome Release 64-1-1, reverse complement, Verified ORF, "Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); similar to mammalian proteasomal modulator subunit; non-essential gene; interacts with Rpn4p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40555    220   PSMD9_YEAST Probable 26S proteasome regulator...2203e-160     449     100     100GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0070682; P:proteasome regulatory particle assembly; IDA:SGD.
2Q9WTV5    222   PSMD9_RAT 26S proteasome non-ATPase regulator...1998e-37     134     39     59GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0043425; F:bHLH transcription factor binding; IDA:BHF-UCL.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0003713; F:transcription coactivator activity; IDA:BHF-UCL.
GO:0006915; P:apoptotic process; IMP:BHF-UCL.::GO:0046676; P:negative regulation of insulin secretion; IMP:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB.
3Q3SZ19    221   PSMD9_BOVIN 26S proteasome non-ATPase regulat...1954e-35     129     37     60
GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB.
4O00233    223   PSMD9_HUMAN 26S proteasome non-ATPase regulat...1974e-34     127     37     57GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005838; C:proteasome regulatory particle; NAS:UniProtKB.
GO:0043425; F:bHLH transcription factor binding; ISS:BHF-UCL.::GO:0003713; F:transcription coactivator activity; ISS:BHF-UCL.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0046676; P:negative regulation of insulin secretion; ISS:BHF-UCL.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0032024; P:positive regulation of insulin secretion; ISS:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:BHF-UCL.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070682; P:proteasome regulatory particle assembly; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
5Q9CR00    222   PSMD9_MOUSE 26S proteasome non-ATPase regulat...1961e-33     125     37     59GO:0005634; C:nucleus; ISS:BHF-UCL.
GO:0043425; F:bHLH transcription factor binding; ISS:BHF-UCL.::GO:0003713; F:transcription coactivator activity; ISS:BHF-UCL.
GO:0046676; P:negative regulation of insulin secretion; ISS:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; ISS:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:BHF-UCL.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB.
6Q10920    197   PSMD9_CAEEL Probable 26S proteasome non-ATPas...1902e-21     92     31     55
GO:0005515; F:protein binding; IPI:IntAct.
7O94393    213   PSMD9_SCHPO Probable 26S proteasome regulator...2219e-16     76.6     27     46GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IC:PomBase.::GO:0070682; P:proteasome regulatory particle assembly; ISS:PomBase.
8Q552Y8    262   PSMD9_DICDI Probable 26S proteasome non-ATPas...2360.00000000000001     73.6     26     43GO:0005838; C:proteasome regulatory particle; ISS:dictyBase.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:dictyBase.
9Q9RPP2    422   EEP_ENTFA Probable protease eep OS=Enterococc...690.004     41.2     30     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
10Q9Z6T0    488   DEGPL_CHLPN Probable periplasmic serine endop...910.007     40.8     30     56GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB.
GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
11Q8WWI1    1683   LMO7_HUMAN LIM domain only protein 7 OS=Homo ...660.051     38.1     33     59GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005634; C:nucleus; TAS:ProtInc.::GO:0000151; C:ubiquitin ligase complex; NAS:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
12Q9CJL2    442   Y1991_PASMU Putative zinc metalloprotease PM1...790.097     37     32     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
13O83609    450   Y600_TREPA Putative zinc metalloprotease TP_0...720.16     36.2     29     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
14P72780    394   HHOA_SYNY3 Putative serine protease HhoA OS=S...1180.3     35.4     20     44GO:0030288; C:outer membrane-bounded periplasmic space; IDA:UniProtKB.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
15P44936    443   Y918_HAEIN Putative zinc metalloprotease HI_0...790.47     35     27     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
16Q8SQG9    316   NHRF2_RABIT Na(+)/H(+) exchange regulatory co...780.54     34.7     28     53GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
17Q9PL97    497   DEGPL_CHLMU Probable periplasmic serine endop...910.56     34.7     27     54GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB.
GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
18Q9WZZ2    501   Y890_THEMA Putative zinc metalloprotease TM_0...780.57     34.7     31     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
19A6YFB5    459   HTRA1_XENLA Serine protease HTRA1 OS=Xenopus ...620.72     34.3     34     58GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro.
20Q9S342    226   RSEP_PHOLU Protease rseP OS=Photorhabdus lumi...670.77     33.9     27     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
21Q9JHL1    337   NHRF2_MOUSE Na(+)/H(+) exchange regulatory co...420.87     33.9     31     57GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.
GO:0019902; F:phosphatase binding; IPI:UniProtKB.
GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase cascade; IGI:MGI.
22Q15599    337   NHRF2_HUMAN Na(+)/H(+) exchange regulatory co...420.93     33.9     31     57GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0019902; F:phosphatase binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0005102; F:receptor binding; IPI:UniProtKB.
GO:0006461; P:protein complex assembly; TAS:ProtInc.
23P26982    475   DEGP_SALTY Periplasmic serine endoprotease De...1591.1     33.9     25     45GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB.
GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; ISS:UniProtKB.::GO:0006457; P:protein folding; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; ISS:UniProtKB.::GO:0009266; P:response to temperature stimulus; ISS:UniProtKB.
24P39099    455   DEGQ_ECOLI Periplasmic pH-dependent serine en...681.3     33.5     31     54GO:0042597; C:periplasmic space; IDA:UniProtKB.
GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
GO:0051603; P:proteolysis involved in cellular protein catabolic process; IDA:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
25Q6CWI4    1651   HIR3_KLULA Histone transcription regulator 3 ...861.4     33.9     29     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26O34358    449   HTRA_BACSU Serine protease Do-like HtrA OS=Ba...601.5     33.5     35     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
27A4D2P6    1211   GRD2I_HUMAN Delphilin OS=Homo sapiens (Human)...611.9     33.1     30     56GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
28P18584    497   DEGPL_CHLTR Probable periplasmic serine endop...912.3     32.7     24     54GO:0030288; C:outer membrane-bounded periplasmic space; ISS:UniProtKB.
GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
29A4IHA1    460   HTRA1_XENTR Serine protease HTRA1 OS=Xenopus ...692.4     32.7     29     52GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0005520; F:insulin-like growth factor binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0001558; P:regulation of cell growth; IEA:InterPro.
30O61967    699   LAP1_CAEEL Protein lap1 OS=Caenorhabditis ele...812.6     32.7     26     48GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0016323; C:basolateral plasma membrane; IDA:WormBase.
GO:0030029; P:actin filament-based process; IMP:WormBase.::GO:0007155; P:cell adhesion; IMP:WormBase.::GO:0007043; P:cell-cell junction assembly; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007163; P:establishment or maintenance of cell polarity; IEP:UniProtKB.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0030728; P:ovulation; IMP:WormBase.::GO:0060465; P:pharynx development; IMP:WormBase.::GO:0015031; P:protein transport; IEP:UniProtKB.::GO:0045108; P:regulation of intermediate filament polymerization or depolymerization; IMP:UniProtKB.
31Q0QWG9    1203   GRD2I_MOUSE Delphilin OS=Mus musculus (Mouse)...613.7     32.3     28     56GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:MGI.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.::GO:0007216; P:G-protein coupled glutamate receptor signaling pathway; TAS:MGI.::GO:0060292; P:long term synaptic depression; IMP:MGI.
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