Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL005W
Length:
701
Number of sequences:
5887
Description:
YIL005W EPS1 SGDID:S000001267, Chr IX from 345692-347797, Genome Release 64-1-1, Verified ORF, "ER protein with chaperone and co-chaperone activity, involved in retention of resident ER proteins; has a role in recognizing proteins targeted for ER-associated degradation (ERAD), member of the protein disulfide isomerase family"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P38660    439   PDIA6_MESAU Protein disulfide-isomerase A6 OS...910.0001     48.5     27     51GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0003756; F:protein disulfide isomerase activity; ISS:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0070527; P:platelet aggregation; ISS:UniProtKB.
32Q942L2    371   PDI22_ORYSJ Protein disulfide isomerase-like ...670.009     42.4     25     55GO:0005783; C:endoplasmic reticulum; IEA:InterPro.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
33Q6NRT6    796   DJC10_XENLA DnaJ homolog subfamily C member 1...860.003     44.7     30     50GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; IEA:InterPro.
34Q9H3N1    280   TMX1_HUMAN Thioredoxin-related transmembrane ...920.000003     53.1     34     52GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:UniProtKB.
GO:0030612; F:arsenate reductase (thioredoxin) activity; NAS:UniProtKB.::GO:0015036; F:disulfide oxidoreductase activity; IDA:UniProtKB.
GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006260; P:DNA replication; NAS:UniProtKB.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:UniProtKB.::GO:0045321; P:leukocyte activation; NAS:UniProtKB.::GO:0045927; P:positive regulation of growth; NAS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006950; P:response to stress; NAS:UniProtKB.::GO:0007165; P:signal transduction; NAS:UniProtKB.
35P09102    515   PDIA1_CHICK Protein disulfide-isomerase OS=Ga...660.002     45.1     30     59GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
36Q15084    440   PDIA6_HUMAN Protein disulfide-isomerase A6 OS...690.00007     49.7     30     55GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; TAS:ProtInc.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; TAS:ProtInc.
37Q5R6T1    440   PDIA6_PONAB Protein disulfide-isomerase A6 OS...690.00007     49.7     30     55GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0003756; F:protein disulfide isomerase activity; ISS:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0070527; P:platelet aggregation; ISS:UniProtKB.
38Q8VBT0    278   TMX1_MOUSE Thioredoxin-related transmembrane ...910.00001     51.2     33     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
39Q86IA3    363   PDI1_DICDI Protein disulfide-isomerase 1 OS=D...2330.00001     51.6     21     41GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IGI:dictyBase.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; ISS:dictyBase.
40P80284    513   PDI_HORVU Protein disulfide-isomerase OS=Hord...1050.0002     48.1     22     50GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
41Q4VIT4    505   PDIA3_CHLAE Protein disulfide-isomerase A3 OS...1834     34.3     26     40GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
42Q5RDG4    505   PDIA3_PONAB Protein disulfide-isomerase A3 OS...1837.4     33.5     26     40GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
43P30101    505   PDIA3_HUMAN Protein disulfide-isomerase A3 OS...1837.4     33.5     26     40GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; TAS:Reactome.
GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0004629; F:phospholipase C activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003756; F:protein disulfide isomerase activity; TAS:ProtInc.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0006457; P:protein folding; TAS:Reactome.::GO:0006606; P:protein import into nucleus; TAS:ProtInc.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.::GO:0006621; P:protein retention in ER lumen; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
44Q00216    359   TIGA_ASPNG Protein disulfide-isomerase tigA O...1230.003     44.3     25     47GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
45P29828    512   PDI_MEDSA Protein disulfide-isomerase OS=Medi...1090.0004     47.4     24     53GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
46Q869Z0    409   Y5025_DICDI Putative protein disulfide-isomer...810.00002     51.6     31     56GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
47P11598    505   PDIA3_RAT Protein disulfide-isomerase A3 OS=R...970.01     42.7     30     54GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
48P27773    505   PDIA3_MOUSE Protein disulfide-isomerase A3 OS...970.009     42.7     30     54GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.
49P38657    505   PDIA3_BOVIN Protein disulfide-isomerase A3 OS...1821.2     36.2     26     41GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0043065; P:positive regulation of apoptotic process; ISS:AgBase.
50Q67UF5    441   PDI23_ORYSJ Protein disulfide isomerase-like ...830.00005     50.1     28     53GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
51Q9FF55    597   PDI14_ARATH Protein disulfide isomerase-like ...880.00002     51.2     27     57GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006979; P:response to oxidative stress; IDA:TAIR.
52Q54EN4    513   PDI2_DICDI Protein disulfide-isomerase 2 OS=D...630.028     41.2     30     62GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:dictyBase.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; ISS:dictyBase.::GO:0009617; P:response to bacterium; IEP:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase.
53P07237    508   PDIA1_HUMAN Protein disulfide-isomerase OS=Ho...580.002     45.1     33     60GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.::GO:0005576; C:extracellular region; NAS:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0004656; F:procollagen-proline 4-dioxygenase activity; IDA:MGI.::GO:0003756; F:protein disulfide isomerase activity; TAS:ProtInc.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006629; P:lipid metabolic process; TAS:Reactome.::GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.::GO:0018401; P:peptidyl-proline hydroxylation to 4-hydroxy-L-proline; IDA:MGI.
54Q9T042    480   PDI54_ARATH Protein disulfide-isomerase 5-4 O...730.00003     50.8     27     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
55Q2HWU2    510   PDIA1_MACFU Protein disulfide-isomerase OS=Ma...580.003     44.7     33     60GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
56Q5R5B6    508   PDIA1_PONAB Protein disulfide-isomerase OS=Po...580.002     45.1     33     60GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
57Q29RV1    643   PDIA4_BOVIN Protein disulfide-isomerase A4 OS...680.023     41.6     32     57GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
58Q9SRG3    508   PDI12_ARATH Protein disulfide isomerase-like ...910.002     45.1     30     55GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
59Q8JG64    505   PDIA3_CHICK Protein disulfide-isomerase A3 OS...1841.1     36.2     27     41GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
60Q69ST6    545   PID13_ORYSJ Protein disulfide isomerase-like ...1060.003     44.3     25     49GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
61P05307    510   PDIA1_BOVIN Protein disulfide-isomerase OS=Bo...580.002     45.1     33     60GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; ISS:AgBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0004656; F:procollagen-proline 4-dioxygenase activity; ISS:AgBase.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0018401; P:peptidyl-proline hydroxylation to 4-hydroxy-L-proline; ISS:AgBase.
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