Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL001W
Length:
513
Number of sequences:
5887
Description:
YIL001W YIL001W SGDID:S000001263, Chr IX from 353940-355481, Genome Release 64-1-1, Uncharacterized ORF, "Putative protein of unknown function; contains a BTB/POZ domain which generally function in protein interactions; deletion slightly improved competitive fitness in rich media; GFP-tagged protein is localized to the cytoplasm"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61O75832    226   PSD10_HUMAN 26S proteasome non-ATPase regulat...540.015     40.8     39     57GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005838; C:proteasome regulatory particle; TAS:ProtInc.
GO:0008134; F:transcription factor binding; IPI:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IDA:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IDA:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070682; P:proteasome regulatory particle assembly; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
62Q61858    372   GPAN1_MOUSE G patch domain and ankyrin repeat...730.015     41.2     33     51
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
63Q8NB46    1076   ANR52_HUMAN Serine/threonine-protein phosphat...811.8     35     30     52
64Q9ULH0    1771   KDIS_HUMAN Kinase D-interacting substrate of ...714     33.9     30     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.
65Q9EQG6    1762   KDIS_RAT Kinase D-interacting substrate of 22...719.7     32.7     30     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0019901; F:protein kinase binding; IDA:RGD.::GO:0019887; F:protein kinase regulator activity; IDA:RGD.
66Q54XY6    908   Y0019_DICDI Probable serine/threonine-protein...780.017     41.6     33     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
67P62775    118   MTPN_RAT Myotrophin OS=Rattus norvegicus (Rat...560.052     37.4     30     55GO:0030424; C:axon; IDA:RGD.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006584; P:catecholamine metabolic process; IEP:RGD.::GO:0021707; P:cerebellar granule cell differentiation; IEP:RGD.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IMP:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.::GO:0010557; P:positive regulation of macromolecule biosynthetic process; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0051247; P:positive regulation of protein metabolic process; IDA:UniProtKB.::GO:2000812; P:regulation of barbed-end actin filament capping; ISS:UniProtKB.::GO:0043403; P:skeletal muscle tissue regeneration; IEP:RGD.::GO:0051146; P:striated muscle cell differentiation; IEP:RGD.
68P62774    118   MTPN_MOUSE Myotrophin OS=Mus musculus (Mouse)...560.052     37.4     30     55GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0010557; P:positive regulation of macromolecule biosynthetic process; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0051247; P:positive regulation of protein metabolic process; ISS:UniProtKB.::GO:2000812; P:regulation of barbed-end actin filament capping; ISS:UniProtKB.
69P58546    118   MTPN_HUMAN Myotrophin OS=Homo sapiens (Human)...560.052     37.4     30     55GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0008290; C:F-actin capping protein complex; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016049; P:cell growth; IDA:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IMP:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0010557; P:positive regulation of macromolecule biosynthetic process; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0051247; P:positive regulation of protein metabolic process; ISS:UniProtKB.::GO:2000812; P:regulation of barbed-end actin filament capping; IDA:UniProtKB.::GO:0016202; P:regulation of striated muscle tissue development; NAS:UniProtKB.::GO:0006417; P:regulation of translation; NAS:UniProtKB.
70Q863Z4    118   MTPN_CANFA Myotrophin OS=Canis familiaris (Do...560.052     37.4     30     55GO:0030424; C:axon; ISS:AgBase.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0010557; P:positive regulation of macromolecule biosynthetic process; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0051247; P:positive regulation of protein metabolic process; ISS:UniProtKB.::GO:2000812; P:regulation of barbed-end actin filament capping; ISS:UniProtKB.
71Q3T0F7    118   MTPN_BOVIN Myotrophin OS=Bos taurus (Bovine)....560.052     37.4     30     55GO:0030424; C:axon; ISS:AgBase.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0010557; P:positive regulation of macromolecule biosynthetic process; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0051247; P:positive regulation of protein metabolic process; ISS:UniProtKB.::GO:2000812; P:regulation of barbed-end actin filament capping; ISS:UniProtKB.
72Q6ZW76    656   ANKS3_HUMAN Ankyrin repeat and SAM domain-con...640.018     41.6     36     52
73Q6RI86    1125   TRPA1_RAT Transient receptor potential cation...710.022     41.2     38     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
74Q96T49    567   PP16B_HUMAN Protein phosphatase 1 regulatory ...580.023     41.2     41     55GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0019903; F:protein phosphatase binding; NAS:UniProtKB.
GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.::GO:0007165; P:signal transduction; NAS:UniProtKB.
75Q9Z2X2    231   PSD10_MOUSE 26S proteasome non-ATPase regulat...540.023     40     39     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB.
76Q95N27    568   PP16B_BOVIN Protein phosphatase 1 regulatory ...580.024     40.8     41     55GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0051489; P:regulation of filopodium assembly; IMP:UniProtKB.
77Q9Z2X3    231   PSD10_RAT 26S proteasome non-ATPase regulator...680.024     40     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB.
78Q5ZLC8    1073   ANR52_CHICK Serine/threonine-protein phosphat...811.5     35.4     30     49
79Q8VHQ3    568   PP16B_MOUSE Protein phosphatase 1 regulatory ...580.025     40.8     41     55GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.
80Q66H07    344   FANK1_RAT Fibronectin type 3 and ankyrin repe...742.4     34.3     32     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
81Q8CE33    709   KLH11_MOUSE Kelch-like protein 11 OS=Mus musc...1610.028     40.8     25     46GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
82Q9DAM9    344   FANK1_MOUSE Fibronectin type 3 and ankyrin re...510.029     40.4     43     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
83Q502K3    1071   ANR52_DANRE Serine/threonine-protein phosphat...660.84     36.2     38     52
84Q9VCA8    4001   ANKHM_DROME Ankyrin repeat and KH domain-cont...6810     32.7     31     47GO:0005811; C:lipid particle; IDA:FlyBase.
GO:0019887; F:protein kinase regulator activity; IGI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0019730; P:antimicrobial humoral response; IMP:FlyBase.::GO:0051298; P:centrosome duplication; IMP:FlyBase.::GO:0001751; P:compound eye photoreceptor cell differentiation; IMP:FlyBase.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IGI:FlyBase.
85Q8WZ74    1663   CTTB2_HUMAN Cortactin-binding protein 2 OS=Ho...600.031     40.8     38     55
86Q2IBF7    1663   CTTB2_GORGO Cortactin-binding protein 2 OS=Go...600.031     40.8     38     55
87A2AS55    361   ANR16_MOUSE Ankyrin repeat domain-containing ...510.032     40.4     39     57
88Q9D738    308   ASB12_MOUSE Ankyrin repeat and SOCS box prote...970.033     40     31     47
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
89Q8TC84    345   FANK1_HUMAN Fibronectin type 3 and ankyrin re...510.033     40     41     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
90Q86U10    573   LPP60_HUMAN 60 kDa lysophospholipase OS=Homo ...640.5     36.6     38     52
GO:0003847; F:1-alkyl-2-acetylglycerophosphocholine esterase activity; IEA:EC.::GO:0004067; F:asparaginase activity; IEA:EC.::GO:0004622; F:lysophospholipase activity; IEA:EC.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
91C9JTQ0    380   ANR63_HUMAN Ankyrin repeat domain-containing ...570.039     40     30     53
records
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