Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR207C
Length:
526
Number of sequences:
5887
Description:
YHR207C SET5 SGDID:S000001250, Chr VIII from 516485-514905, Genome Release 64-1-1, reverse complement, Verified ORF, "Zinc-finger protein of unknown function, contains one canonical and two unusual fingers in unusual arrangements; deletion enhances replication of positive-strand RNA virus"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31O94256    483   SET6_SCHPO SET domain and MYND-type zinc fing...996.1     33.1     30     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016571; P:histone methylation; IC:PomBase.
32P83501    448   MSTAB_DROME Protein msta, isoform B OS=Drosop...1140.0003     47     26     44
GO:0042826; F:histone deacetylase binding; ISS:FlyBase.
GO:0010629; P:negative regulation of gene expression; ISS:FlyBase.
33Q12529    373   SET6_YEAST Potential protein lysine methyltra...810.0004     46.6     33     51
GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
34Q54DL6    521   Y2140_DICDI SET and MYND domain-containing pr...720.001     45.4     32     51
GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
35Q8IYR2    804   SMYD4_HUMAN SET and MYND domain-containing pr...1160.001     45.4     29     41
GO:0008270; F:zinc ion binding; IEA:InterPro.
36Q5RGL7    434   SMY2B_DANRE N-lysine methyltransferase SMYD2-...3300.004     43.5     21     34GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
37Q9NRG4    433   SMYD2_HUMAN N-lysine methyltransferase SMYD2 ...790.004     43.5     27     51GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; IDA:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
38Q6GPQ4    421   SMYD5_XENLA SET and MYND domain-containing pr...1160.086     38.9     27     47
GO:0008270; F:zinc ion binding; IEA:InterPro.
39Q5R5X9    804   SMYD4_PONAB SET and MYND domain-containing pr...890.004     43.5     30     46
GO:0008270; F:zinc ion binding; IEA:InterPro.
40Q5ZIZ2    420   SMYD5_CHICK SET and MYND domain-containing pr...1070.075     39.3     27     44
GO:0008270; F:zinc ion binding; IEA:InterPro.
41Q5PP37    473   ATXR2_ARATH Histone-lysine N-methyltransferas...1210.011     42     28     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
42O46040    462   MSTAA_DROME Protein msta, isoform A OS=Drosop...1140.016     41.6     25     41
GO:0042826; F:histone deacetylase binding; ISS:FlyBase.
GO:0010629; P:negative regulation of gene expression; ISS:FlyBase.
43E1C5V0    436   SMYD2_CHICK N-lysine methyltransferase SMYD2 ...790.016     41.6     27     49GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
44Q0P585    433   SMYD2_BOVIN N-lysine methyltransferase SMYD2 ...790.023     40.8     25     49GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
45C3RZA1    433   SMYD2_PIG N-lysine methyltransferase SMYD2 OS...790.024     40.8     25     49GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
46Q3ECY6    558   SDG41_ARATH Protein SET DOMAIN GROUP 41 OS=Ar...1160.028     40.8     25     37
47Q8R5A0    433   SMYD2_MOUSE N-lysine methyltransferase SMYD2 ...790.08     39.3     24     49GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; IDA:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
48Q7M6Z3    433   SMYD2_RAT N-lysine methyltransferase SMYD2 OS...790.083     39.3     24     49GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
49Q1LY77    1844   SE1BA_DANRE Histone-lysine N-methyltransferas...730.092     39.3     29     49GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
50Q6GN68    430   SMY2B_XENLA N-lysine methyltransferase SMYD2-...820.11     38.5     23     48GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
51Q18221    1507   SET2_CAEEL Probable histone-lysine N-methyltr...490.28     37.7     37     61GO:0005634; C:nucleus; IDA:WormBase.
GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:WormBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
52Q8X225    331   DIM5_NEUCR Histone-lysine N-methyltransferase...520.29     37.4     42     56GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
53Q59XV0    844   SET2_CANAL Histone-lysine N-methyltransferase...410.38     37.4     39     63GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
54Q6BM04    731   SET2_DEBHA Histone-lysine N-methyltransferase...410.48     37     41     66GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
55Q4I8C9    662   SET9_GIBZE Histone-lysine N-methyltransferase...390.58     36.6     41     62GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
56Q4PBL3    972   SET2_USTMA Histone-lysine N-methyltransferase...410.58     36.6     39     61GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
57Q7ZXV5    430   SMY2A_XENLA N-lysine methyltransferase SMYD2-...820.68     36.2     22     46GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.::GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.::GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
58Q9UPS6    1923   SET1B_HUMAN Histone-lysine N-methyltransferas...730.72     36.6     27     49GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
59Q8CFT2    1985   SET1B_MOUSE Histone-lysine N-methyltransferas...730.73     36.6     27     49GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
60Q8BTK5    799   SMYD4_MOUSE SET and MYND domain-containing pr...890.89     36.2     28     42
GO:0008270; F:zinc ion binding; IEA:InterPro.
61O15047    1707   SET1A_HUMAN Histone-lysine N-methyltransferas...731.2     35.8     27     49GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB.
GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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