Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR205W
Length:
824
Number of sequences:
5887
Description:
YHR205W SCH9 SGDID:S000001248, Chr VIII from 509363-511837, Genome Release 64-1-1, Verified ORF, "Protein kinase involved in transcriptional activation of osmostress-responsive genes; regulates G1 progression, cAPK activity, nitrogen activation of the FGM pathway; involved in life span regulation; homologous to mammalian Akt/PKB"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
541Q86AD7    392   MYLKB_DICDI Probable myosin light chain kinas...2756e-32     133     32     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0007165; P:signal transduction; ISS:dictyBase.
542Q940H6    362   SRK2E_ARATH Serine/threonine-protein kinase S...2686e-32     132     32     50GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; TAS:TAIR.::GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0040007; P:growth; IMP:TAIR.::GO:0048366; P:leaf development; IMP:TAIR.::GO:0010359; P:regulation of anion channel activity; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:TAIR.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR.::GO:0009651; P:response to salt stress; IDA:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR.::GO:0010118; P:stomatal movement; IMP:TAIR.::GO:0005985; P:sucrose metabolic process; IMP:TAIR.::GO:0019432; P:triglyceride biosynthetic process; IMP:TAIR.::GO:0006636; P:unsaturated fatty acid biosynthetic process; IMP:TAIR.
543Q54SJ5    312   MYLKC_DICDI Probable myosin light chain kinas...2436e-32     131     34     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0007165; P:signal transduction; ISS:dictyBase.
544Q95266    499   KCC2D_PIG Calcium/calmodulin-dependent protei...2707e-32     134     33     51GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB.
545Q6PHZ2    499   KCC2D_MOUSE Calcium/calmodulin-dependent prot...2707e-32     134     33     51GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0031594; C:neuromuscular junction; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0030315; C:T-tubule; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0006816; P:calcium ion transport; IDA:MGI.::GO:0060048; P:cardiac muscle contraction; IDA:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:MGI.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB.
546Q13557    499   KCC2D_HUMAN Calcium/calmodulin-dependent prot...2707e-32     134     33     51GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IMP:UniProtKB.::GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; TAS:UniProtKB.::GO:0001558; P:regulation of cell growth; NAS:UniProtKB.::GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; TAS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome.
547Q9JLM8    756   DCLK1_MOUSE Serine/threonine-protein kinase D...2737e-32     136     32     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0048675; P:axon extension; IGI:MGI.::GO:0021952; P:central nervous system projection neuron axonogenesis; IGI:MGI.::GO:0048813; P:dendrite morphogenesis; IGI:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0001764; P:neuron migration; IGI:MGI.
548Q28GW8    652   MELK_XENTR Maternal embryonic leucine zipper ...2758e-32     135     29     51GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
549Q2HJF7    488   KCC2D_BOVIN Calcium/calmodulin-dependent prot...2709e-32     134     33     51GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB.
550P50528    683   PLO1_SCHPO Serine/threonine-protein kinase pl...2589e-32     135     32     55GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-KW.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0034605; P:cellular response to heat; IMP:PomBase.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:PomBase.::GO:0031031; P:positive regulation of septation initiation signaling cascade; IMP:PomBase.::GO:0010687; P:site selection involved in cell cycle cytokinesis; IMP:PomBase.::GO:0090307; P:spindle assembly involved in mitosis; IMP:PomBase.::GO:0007089; P:traversing start control point of mitotic cell cycle; TAS:PomBase.
551Q54MH0    749   FHKD_DICDI Probable serine/threonine-protein ...2861e-31     136     31     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000077; P:DNA damage checkpoint; ISS:dictyBase.
552P54646    552   AAPK2_HUMAN 5'-AMP-activated protein kinase c...2481e-31     134     34     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0006853; P:carnitine shuttle; TAS:Reactome.::GO:0007050; P:cell cycle arrest; TAS:Reactome.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0042304; P:regulation of fatty acid biosynthetic process; TAS:Reactome.::GO:0046320; P:regulation of fatty acid oxidation; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
553P34244    1518   HSL1_YEAST Probable serine/threonine-protein ...3121e-31     137     29     50GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005940; C:septin ring; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000078; P:cell shape checkpoint; TAS:SGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:SGD.::GO:0046777; P:protein autophosphorylation; IMP:SGD.::GO:0000135; P:septin checkpoint; IGI:SGD.
554Q9FMP5    528   CDPKH_ARATH Calcium-dependent protein kinase ...2721e-31     134     32     51GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0080092; P:regulation of pollen tube growth; IMP:TAIR.
555Q5RD00    552   AAPK2_PONAB 5'-AMP-activated protein kinase c...2491e-31     134     34     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004679; F:AMP-activated protein kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
556Q8N568    766   DCLK2_HUMAN Serine/threonine-protein kinase D...2731e-31     135     30     53GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
557Q9P0L2    795   MARK1_HUMAN Serine/threonine-protein kinase M...2282e-31     135     34     54GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0015630; C:microtubule cytoskeleton; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.::GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
558Q09137    552   AAPK2_RAT 5'-AMP-activated protein kinase cat...2482e-31     134     34     53GO:0031588; C:AMP-activated protein kinase complex; IDA:RGD.::GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:RGD.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030674; F:protein binding, bridging; IDA:RGD.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0071417; P:cellular response to organic nitrogen; IEP:RGD.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; IDA:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; IDA:UniProtKB.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; IDA:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; IDA:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0014823; P:response to activity; IDA:RGD.::GO:0031000; P:response to caffeine; IDA:RGD.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
559Q54PB4    481   MYLKE_DICDI Probable myosin light chain kinas...2722e-31     133     31     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:dictyBase.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0007165; P:signal transduction; ISS:dictyBase.
560O96017    543   CHK2_HUMAN Serine/threonine-protein kinase Ch...2722e-31     133     34     50GO:0016605; C:PML body; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0044257; P:cellular protein catabolic process; IMP:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; IMP:UniProtKB.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IDA:UniProtKB.::GO:0006302; P:double-strand break repair; IMP:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0042176; P:regulation of protein catabolic process; IMP:UniProtKB.::GO:0090399; P:replicative senescence; NAS:BHF-UCL.::GO:0072428; P:signal transduction involved in intra-S DNA damage checkpoint; IMP:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
561Q9DG02    475   KCC2D_XENLA Calcium/calmodulin-dependent prot...2702e-31     132     33     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
562O15075    740   DCLK1_HUMAN Serine/threonine-protein kinase D...2732e-31     135     31     52GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
GO:0016197; P:endosome transport; NAS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009615; P:response to virus; IEP:UniProtKB.
563Q5EG47    559   AAPK1_MOUSE 5'-AMP-activated protein kinase c...2492e-31     133     34     54GO:0031588; C:AMP-activated protein kinase complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0035174; F:histone serine kinase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0019395; P:fatty acid oxidation; IMP:MGI.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0006006; P:glucose metabolic process; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; IDA:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; IMP:UniProtKB.::GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; IMP:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
564P08413    542   KCC2B_RAT Calcium/calmodulin-dependent protei...2702e-31     133     33     51GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0060291; P:long-term synaptic potentiation; IMP:MGI.::GO:0061003; P:positive regulation of dendritic spine morphogenesis; IMP:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
565Q6DBX4    860   GWL_DANRE Serine/threonine-protein kinase gre...1348e-16     85.5     39     56GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051721; F:protein phosphatase 2A binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0034048; P:negative regulation of protein phosphatase type 2A activity; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0002574; P:thrombocyte differentiation; IMP:ZFIN.
566Q13554    666   KCC2B_HUMAN Calcium/calmodulin-dependent prot...2702e-31     134     33     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051924; P:regulation of calcium ion transport; TAS:UniProtKB.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; TAS:UniProtKB.::GO:0014733; P:regulation of skeletal muscle adaptation; TAS:UniProtKB.::GO:0051823; P:regulation of synapse structural plasticity; TAS:UniProtKB.
567P57059    783   SIK1_HUMAN Serine/threonine-protein kinase SI...2652e-31     135     31     52GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008140; F:cAMP response element binding protein binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0055007; P:cardiac muscle cell differentiation; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0032792; P:negative regulation of CREB transcription factor activity; ISS:UniProtKB.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0010830; P:regulation of myotube differentiation; ISS:UniProtKB.::GO:0002028; P:regulation of sodium ion transport; ISS:UniProtKB.::GO:0072333; P:signal transduction by p53 class mediator resulting in induction of anoikis; IMP:BHF-UCL.
568Q6NSM8    1187   SIK3_DANRE Serine/threonine-protein kinase SI...2462e-31     136     34     51
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
569P28652    542   KCC2B_MOUSE Calcium/calmodulin-dependent prot...2702e-31     133     33     51GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:MGI.
GO:0060466; P:activation of meiosis involved in egg activation; IMP:MGI.::GO:0006816; P:calcium ion transport; IMP:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.::GO:0031558; P:induction of apoptosis in response to chemical stimulus; IDA:MGI.::GO:0002030; P:inhibitory G-protein coupled receptor phosphorylation; IDA:MGI.::GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:MGI.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI.::GO:0032222; P:regulation of synaptic transmission, cholinergic; IMP:MGI.::GO:0046686; P:response to cadmium ion; IDA:MGI.
570Q28948    552   AAPK2_PIG 5'-AMP-activated protein kinase cat...2482e-31     133     34     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
571Q8C0V7    499   SMKW_MOUSE Sperm motility kinase W OS=Mus mus...2742e-31     132     33     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.
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