Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR204W
Length:
796
Number of sequences:
5887
Description:
YHR204W MNL1 SGDID:S000001247, Chr VIII from 506319-508709, Genome Release 64-1-1, Verified ORF, "Alpha-1,2-specific exomannosidase of the endoplasmic reticulum; in complex with Pdi1p, generates a Man7GlcNac2 oligosaccharide signal on glycoproteins destined for ubiquitin-proteasome degradation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38888    796   MNL1_YEAST ER degradation-enhancing alpha-man...7960     1653     100     100GO:0005788; C:endoplasmic reticulum lumen; IDA:SGD.::GO:0016020; C:membrane; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030246; F:carbohydrate binding; IMP:SGD.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IMP:SGD.
GO:0030433; P:ER-associated protein catabolic process; IMP:SGD.::GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
2Q925U4    652   EDEM1_MOUSE ER degradation-enhancing alpha-ma...4956e-109     353     41     60GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:MGI.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:InterPro.::GO:0051787; F:misfolded protein binding; ISS:UniProtKB.
GO:0030433; P:ER-associated protein catabolic process; IDA:MGI.::GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
3Q92611    657   EDEM1_HUMAN ER degradation-enhancing alpha-ma...4951e-108     353     41     59GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051787; F:misfolded protein binding; IDA:UniProtKB.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0006457; P:protein folding; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
4O94726    787   MNL1_SCHPO ER degradation-enhancing alpha-man...5094e-106     350     38     57GO:0005829; C:cytosol; IDA:PomBase.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030246; F:carbohydrate binding; ISS:PomBase.
GO:0030433; P:ER-associated protein catabolic process; ISS:PomBase.::GO:0006516; P:glycoprotein catabolic process; ISS:PomBase.::GO:0006517; P:protein deglycosylation; ISS:PomBase.::GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
5Q9FG93    624   MNS4_ARATH Probable alpha-mannosidase I MNS4 ...5042e-87     295     37     52GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:InterPro.
6Q9BV94    578   EDEM2_HUMAN ER degradation-enhancing alpha-ma...5121e-84     286     36     53GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0006457; P:protein folding; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.::GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
7Q6GQB9    913   EDEM3_XENLA ER degradation-enhancing alpha-ma...5253e-81     285     35     52GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:InterPro.
GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
8Q9SXC9    574   MNS5_ARATH Probable alpha-mannosidase I MNS5 ...5013e-81     277     34     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:InterPro.
9Q2HXL6    931   EDEM3_MOUSE ER degradation-enhancing alpha-ma...5211e-80     283     36     52GO:0005788; C:endoplasmic reticulum lumen; IDA:MGI.::GO:0016020; C:membrane; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004569; F:glycoprotein endo-alpha-1,2-mannosidase activity; IDA:MGI.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:InterPro.
GO:0006516; P:glycoprotein catabolic process; IDA:MGI.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:MGI.::GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
10Q9BZQ6    932   EDEM3_HUMAN ER degradation-enhancing alpha-ma...4992e-78     277     36     53GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:InterPro.
GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0006457; P:protein folding; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.::GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
11Q9C512    560   MNS1_ARATH Mannosyl-oligosaccharide 1,2-alpha...4805e-40     159     28     46GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004559; F:alpha-mannosidase activity; IDA:TAIR.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:EC.
GO:0006491; P:N-glycan processing; IMP:TAIR.::GO:0048364; P:root development; IGI:TAIR.
12Q8H116    572   MNS2_ARATH Mannosyl-oligosaccharide 1,2-alpha...4965e-39     156     27     45GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004559; F:alpha-mannosidase activity; IDA:TAIR.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:EC.
GO:0006491; P:N-glycan processing; IMP:TAIR.::GO:0048364; P:root development; IGI:TAIR.
13O60476    641   MA1A2_HUMAN Mannosyl-oligosaccharide 1,2-alph...4976e-37     151     28     46GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; TAS:ProtInc.
GO:0006491; P:N-glycan processing; TAS:ProtInc.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
14P39098    641   MA1A2_MOUSE Mannosyl-oligosaccharide 1,2-alph...5001e-36     150     28     46GO:0000139; C:Golgi membrane; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:EC.
GO:0009100; P:glycoprotein metabolic process; IMP:MGI.::GO:0048286; P:lung alveolus development; IMP:MGI.::GO:0007585; P:respiratory gaseous exchange; IMP:MGI.
15P45700    655   MA1A1_MOUSE Mannosyl-oligosaccharide 1,2-alph...4908e-34     142     27     47GO:0000139; C:Golgi membrane; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:EC.
16O02773    659   MA1A1_PIG Mannosyl-oligosaccharide 1,2-alpha-...4916e-33     139     27     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:EC.
17P33908    653   MA1A1_HUMAN Mannosyl-oligosaccharide 1,2-alph...4896e-33     139     27     47GO:0005783; C:endoplasmic reticulum; TAS:ProtInc.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; TAS:ProtInc.
GO:0005509; F:calcium ion binding; TAS:ProtInc.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; TAS:ProtInc.
GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
18Q9NR34    630   MA1C1_HUMAN Mannosyl-oligosaccharide 1,2-alph...4936e-32     135     27     46GO:0030173; C:integral to Golgi membrane; TAS:UniProtKB.
GO:0005509; F:calcium ion binding; TAS:UniProtKB.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; TAS:UniProtKB.
GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
19P53624    667   MA121_DROME Mannosyl-oligosaccharide alpha-1,...5141e-31     135     28     46GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:EC.
GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0072347; P:response to anesthetic; IMP:FlyBase.
20Q9UKM7    699   MA1B1_HUMAN Endoplasmic reticulum mannosyl-ol...4952e-30     131     29     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0044322; C:endoplasmic reticulum quality control compartment; TAS:Reactome.::GO:0016021; C:integral to membrane; TAS:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.
GO:0005509; F:calcium ion binding; TAS:UniProtKB.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IDA:UniProtKB.
GO:0030433; P:ER-associated protein catabolic process; IMP:UniProtKB.::GO:0009311; P:oligosaccharide metabolic process; TAS:ProtInc.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0006457; P:protein folding; TAS:Reactome.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
21P45701    469   MA1A1_RABIT Mannosyl-oligosaccharide 1,2-alph...4905e-30     128     26     47GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:EC.
22P53625    643   MA122_DROME Mannosyl-oligosaccharide alpha-1,...5102e-29     128     27     45GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:EC.
GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0072347; P:response to anesthetic; IMP:FlyBase.
23A2AJ15    658   MA1B1_MOUSE Endoplasmic reticulum mannosyl-ol...4848e-29     126     28     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IMP:MGI.
GO:0030433; P:ER-associated protein catabolic process; IMP:MGI.
24B2GUY0    657   MA1B1_RAT Endoplasmic reticulum mannosyl-olig...4842e-28     125     28     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:EC.
25Q2ULB2    510   MNS1B_ASPOR Mannosyl-oligosaccharide alpha-1,...5175e-28     122     26     42GO:0060205; C:cytoplasmic membrane-bounded vesicle lumen; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:EC.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
26B8N417    510   MNS1B_ASPFN Probable mannosyl-oligosaccharide...5175e-28     122     26     42GO:0060205; C:cytoplasmic membrane-bounded vesicle lumen; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:EC.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
27Q93Y37    624   MNS3_ARATH Mannosyl-oligosaccharide 1,2-alpha...5272e-25     115     27     42GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004559; F:alpha-mannosidase activity; IDA:TAIR.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:EC.
GO:0006491; P:N-glycan processing; IMP:TAIR.::GO:0048364; P:root development; IGI:TAIR.
28Q8J0Q0    565   MNS1_CANAX Mannosyl-oligosaccharide 1,2-alpha...5323e-25     114     25     43GO:0016020; C:membrane; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:EC.
29Q0D076    508   MNS1B_ASPTN Probable mannosyl-oligosaccharide...5052e-24     111     26     42GO:0060205; C:cytoplasmic membrane-bounded vesicle lumen; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:EC.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
30Q9P7C3    521   MNS1_SCHPO Endoplasmic reticulum mannosyl-oli...5077e-24     110     28     42GO:0005789; C:endoplasmic reticulum membrane; IC:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IMP:PomBase.
GO:0006487; P:protein N-linked glycosylation; ISS:PomBase.
31P32906    549   MNS1_YEAST Endoplasmic reticulum mannosyl-oli...5197e-24     110     25     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IDA:UniProtKB.
GO:0030433; P:ER-associated protein catabolic process; IMP:SGD.::GO:0006487; P:protein N-linked glycosylation; IMP:SGD.
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