Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR190W
Length:
444
Number of sequences:
5887
Description:
YHR190W ERG9 SGDID:S000001233, Chr VIII from 484845-486179, Genome Release 64-1-1, Verified ORF, "Farnesyl-diphosphate farnesyl transferase (squalene synthase), joins two farnesyl pyrophosphate moieties to form squalene in the sterol biosynthesis pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P29704    444   FDFT_YEAST Squalene synthase OS=Saccharomyces...4440     917     100     100GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IDA:SGD.::GO:0005792; C:microsome; IDA:SGD.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; IDA:SGD.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0051996; F:squalene synthase activity; IDA:SGD.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006696; P:ergosterol biosynthetic process; IMP:SGD.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
2Q9HGZ6    443   FDFT_CANGA Squalene synthase OS=NRRL Y-65) (Y...4400     647     71     83GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; IEA:EC.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0051996; F:squalene synthase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
3Q752X9    441   FDFT_ASHGO Squalene synthase OS=Y-1056) (Yeas...4380     619     68     80GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; IEA:EC.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0051996; F:squalene synthase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
4O74165    443   FDFT_CYBJA Squalene synthase OS=Cyberlindnera...4370     527     60     74GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; IEA:EC.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0051996; F:squalene synthase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
5P78589    448   FDFT_CANAX Squalene synthase OS=Candida albic...4442e-163     475     56     70GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; IEA:EC.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0051996; F:squalene synthase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
6Q9Y753    445   FDFT_YARLI Squalene synthase OS=lipolytica). ...3871e-141     419     51     70GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; IEA:EC.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0051996; F:squalene synthase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
7Q7S4Z6    481   FDFT_NEUCR Probable squalene synthase OS=1257...3934e-123     374     48     64GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; IEA:EC.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0051996; F:squalene synthase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
8P36596    460   FDFT_SCHPO Squalene synthase OS=Schizosacchar...4211e-107     333     41     61GO:0005789; C:endoplasmic reticulum membrane; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; IGI:PomBase.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0051996; F:squalene synthase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006696; P:ergosterol biosynthetic process; IGI:PomBase.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
9Q5R6U3    417   FDFT_PONAB Squalene synthase OS=Pongo abelii ...3403e-100     312     48     64GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; IEA:EC.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0051996; F:squalene synthase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
10P37268    417   FDFT_HUMAN Squalene synthase OS=Homo sapiens ...3403e-100     312     48     64GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; TAS:ProtInc.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; TAS:Reactome.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0051996; F:squalene synthase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
11P53798    416   FDFT_MOUSE Squalene synthase OS=Mus musculus ...3664e-100     312     46     63GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; IEA:EC.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0051996; F:squalene synthase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
12Q02769    416   FDFT_RAT Squalene synthase OS=Rattus norvegic...3945e-99     309     43     61GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; IDA:RGD.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0051996; F:squalene synthase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IMP:RGD.::GO:0045338; P:farnesyl diphosphate metabolic process; IMP:RGD.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
13Q32KR6    417   FDFT_BOVIN Squalene synthase OS=Bos taurus (B...3662e-98     307     46     62GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; IEA:EC.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0051996; F:squalene synthase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
14Q92459    572   FDFT_USTMA Squalene synthase OS=Ustilago mayd...3951e-95     305     43     60GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; IEA:EC.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0051996; F:squalene synthase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
15P53799    410   FDFT_ARATH Squalene synthase OS=Arabidopsis t...3697e-88     280     43     60GO:0005789; C:endoplasmic reticulum membrane; TAS:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; IDA:TAIR.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0051996; F:squalene synthase activity; IEA:EC.
GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.::GO:0016126; P:sterol biosynthetic process; TAS:TAIR.
16P53800    411   FDFT_NICBE Squalene synthase OS=Nicotiana ben...3685e-86     275     42     61GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; IEA:EC.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0051996; F:squalene synthase activity; IEA:EC.
GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
17Q54DR1    416   FDFT_DICDI Squalene synthase OS=Dictyostelium...3404e-76     249     38     60GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; ISS:dictyBase.
GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; ISS:dictyBase.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0051996; F:squalene synthase activity; IEA:EC.
GO:0006695; P:cholesterol biosynthetic process; ISS:dictyBase.::GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
18P21683    309   CRTB_PANAN Phytoene synthase OS=Pantoea anana...2710.00000002     59.3     23     40
GO:0016767; F:geranylgeranyl-diphosphate geranylgeranyltransferase activity; IEA:EC.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
19Q9SSU8    398   PSY_DAUCA Phytoene synthase, chloroplastic OS...2040.0000005     55.1     27     43GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0016767; F:geranylgeranyl-diphosphate geranylgeranyltransferase activity; IEA:EC.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
20P17056    339   CRTB_RHOCB Phytoene synthase OS=Rhodobacter c...2330.000005     51.6     25     39
GO:0016767; F:geranylgeranyl-diphosphate geranylgeranyltransferase activity; IEA:EC.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.::GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.
21P37273    310   PSY2_SOLLC Phytoene synthase 2, chloroplastic...2080.00009     47.8     24     40GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0016767; F:geranylgeranyl-diphosphate geranylgeranyltransferase activity; IEA:EC.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
22P22872    309   CRTB_ESCVU Phytoene synthase OS=Escherichia v...2380.0001     47.4     26     40
GO:0016767; F:geranylgeranyl-diphosphate geranylgeranyltransferase activity; IEA:EC.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
23P37294    337   CRTB_SYNY3 Phytoene synthase OS=Synechocystis...2080.0003     46.6     22     41
GO:0016767; F:geranylgeranyl-diphosphate geranylgeranyltransferase activity; IEA:EC.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
24P49085    410   PSY_MAIZE Phytoene synthase, chloroplastic OS...820.0004     46.2     37     55GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0016767; F:geranylgeranyl-diphosphate geranylgeranyltransferase activity; IEA:EC.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
25P37272    419   PSY_CAPAN Phytoene synthase, chloroplastic OS...2080.0004     46.2     24     40GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0016767; F:geranylgeranyl-diphosphate geranylgeranyltransferase activity; IEA:EC.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
26P37271    422   PSY_ARATH Phytoene synthase, chloroplastic OS...2060.0006     45.4     25     40GO:0009507; C:chloroplast; IDA:TAIR.
GO:0016767; F:geranylgeranyl-diphosphate geranylgeranyltransferase activity; TAS:TAIR.::GO:0046905; F:phytoene synthase activity; TAS:TAIR.
27P53797    423   PSY_NARPS Phytoene synthase, chloroplastic OS...680.0007     45.4     41     59GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0016767; F:geranylgeranyl-diphosphate geranylgeranyltransferase activity; IEA:EC.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
28P08196    412   PSY1_SOLLC Phytoene synthase 1, chloroplastic...720.0008     45.1     38     56GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0016767; F:geranylgeranyl-diphosphate geranylgeranyltransferase activity; IEA:EC.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
29P65860    302   CRTB_MYCTU Probable phytoene synthase OS=Myco...820.001     44.3     30     54
GO:0016767; F:geranylgeranyl-diphosphate geranylgeranyltransferase activity; IEA:EC.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
30P65861    302   CRTB_MYCBO Probable phytoene synthase OS=Myco...820.001     44.3     30     54
GO:0016767; F:geranylgeranyl-diphosphate geranylgeranyltransferase activity; IEA:EC.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
31P54905    355   CRTB_RHOS4 Phytoene synthase OS=158). GN=crtB...2710.003     43.1     23     39
GO:0016767; F:geranylgeranyl-diphosphate geranylgeranyltransferase activity; IEA:EC.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.::GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.
records
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