Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR183W
Length:
489
Number of sequences:
5887
Description:
YHR183W GND1 SGDID:S000001226, Chr VIII from 470960-472429, Genome Release 64-1-1, Verified ORF, "6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone and adaptation to oxidative stress"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61P31937    336   3HIDH_HUMAN 3-hydroxyisobutyrate dehydrogenas...2050.00004     49.3     25     43GO:0005759; C:mitochondrial matrix; TAS:Reactome.
GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; NAS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0009083; P:branched chain family amino acid catabolic process; TAS:Reactome.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; NAS:UniProtKB.
62Q2HJD7    336   3HIDH_BOVIN 3-hydroxyisobutyrate dehydrogenas...2050.00004     49.3     25     43GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
63Q99L13    335   3HIDH_MOUSE 3-hydroxyisobutyrate dehydrogenas...2030.0002     47.4     24     42GO:0005739; C:mitochondrion; IDA:MGI.
GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
64P29266    335   3HIDH_RAT 3-hydroxyisobutyrate dehydrogenase,...2030.0004     46.2     25     42GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
65Q9V8M5    324   3HIDH_DROME Probable 3-hydroxyisobutyrate deh...2060.0006     45.4     24     42GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
66Q0QLF5    301   HMGD_EUBBA 2-(hydroxymethyl)glutarate dehydro...2140.003     43.5     28     45
GO:0043718; F:2-hydroxymethylglutarate dehydrogenase activity; IDA:UniProtKB.::GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0051187; P:cofactor catabolic process; IDA:UniProtKB.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
67P77161    292   GLXR_ECOLI 2-hydroxy-3-oxopropionate reductas...2300.003     43.1     24     41
GO:0008679; F:2-hydroxy-3-oxopropionate reductase activity; IDA:EcoCyc.::GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0009442; P:allantoin assimilation pathway; IEP:EcoCyc.::GO:0009436; P:glyoxylate catabolic process; IMP:EcoCyc.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
68Q55702    290   Y229_SYNY3 Uncharacterized oxidoreductase slr...1930.005     42.4     24     42
GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
69P0ABQ2    294   GARR_ECOLI 2-hydroxy-3-oxopropionate reductas...2060.029     40     25     44
GO:0008679; F:2-hydroxy-3-oxopropionate reductase activity; IDA:EcoCyc.::GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0019582; P:D-galactarate catabolic process; IDA:EcoCyc.::GO:0042838; P:D-glucarate catabolic process; IDA:EcoCyc.::GO:0046487; P:glyoxylate metabolic process; IEA:InterPro.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
70P0ABQ3    294   GARR_ECOL6 2-hydroxy-3-oxopropionate reductas...2060.029     40     25     44
GO:0008679; F:2-hydroxy-3-oxopropionate reductase activity; IEA:EC.::GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0046487; P:glyoxylate metabolic process; IEA:InterPro.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
71Q5WGU2    340   GPDA_BACSK Glycerol-3-phosphate dehydrogenase...2110.072     38.9     24     41GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; IEA:InterPro.
GO:0047952; F:glycerol-3-phosphate dehydrogenase [NAD(P)+ activity; IEA:EC.::GO:0004367; F:glycerol-3-phosphate dehydrogenase [NAD+ activity; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0046168; P:glycerol-3-phosphate catabolic process; IEA:InterPro.]::GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.]
72Q5RKH0    552   GLYR1_RAT Putative oxidoreductase GLYR1 OS=Ra...2390.24     37.7     22     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
73B9DPR3    449   MURD_STACT UDP-N-acetylmuramoylalanine--D-glu...830.3     37.4     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008764; F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
74A4FUF0    553   GLYR1_BOVIN Putative oxidoreductase GLYR1 OS=...2390.34     37.4     22     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
75Q5ZLS7    553   GLYR1_CHICK Putative oxidoreductase GLYR1 OS=...2390.45     37     22     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
76Q49A26    553   GLYR1_HUMAN Putative oxidoreductase GLYR1 OS=...2390.55     36.6     22     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
77Q562D5    534   GLYR1_XENTR Putative oxidoreductase GLYR1 OS=...421     35.4     38     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
78Q175F8    559   GLYR1_AEDAE Putative oxidoreductase GLYR1 hom...371.3     35.4     38     59
GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
79Q5QYC0    378   RLMN_IDILO Ribosomal RNA large subunit methyl...721.8     34.7     32     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0070040; F:rRNA (adenine-C2-)-methyltransferase activity; IEA:EC.
80Q9V3L1    1048   NDST_DROME Bifunctional heparan sulfate N-dea...362.4     34.7     42     67GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015016; F:[heparan sulfate-glucosamine N-sulfotransferase activity; TAS:FlyBase.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0007427; P:epithelial cell migration, open tracheal system; IMP:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0006024; P:glycosaminoglycan biosynthetic process; IMP:UniProtKB.::GO:0007507; P:heart development; NAS:FlyBase.::GO:0015014; P:heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; IMP:UniProtKB.::GO:0008587; P:imaginal disc-derived wing margin morphogenesis; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0048312; P:intracellular distribution of mitochondria; IMP:FlyBase.::GO:0007509; P:mesoderm migration involved in gastrulation; IMP:UniProtKB.::GO:0007428; P:primary branching, open tracheal system; TAS:FlyBase.::GO:0060828; P:regulation of canonical Wnt receptor signaling pathway; IMP:FlyBase.::GO:0090097; P:regulation of decapentaplegic signaling pathway; IMP:FlyBase.::GO:0045570; P:regulation of imaginal disc growth; IMP:FlyBase.::GO:0007367; P:segment polarity determination; IMP:FlyBase.::GO:0048488; P:synaptic vesicle endocytosis; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; IMP:UniProtKB.]
81Q5R7T2    553   GLYR1_PONAB Putative oxidoreductase GLYR1 OS=...432.5     34.3     35     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
82Q5RKN4    462   GLYR1_DANRE Putative oxidoreductase GLYR1 OS=...432.9     34.3     35     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
83Q9C5X3    666   KEULE_ARATH SNARE-interacting protein KEULE O...564.5     33.5     38     59GO:0005829; C:cytosol; IDA:TAIR.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
84Q8CSX6    449   MURD_STAES UDP-N-acetylmuramoylalanine--D-glu...645.6     33.1     34     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008764; F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
85Q5HQ09    449   MURD_STAEQ UDP-N-acetylmuramoylalanine--D-glu...645.6     33.1     34     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008764; F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
86P0A091    449   MURD_STAAU UDP-N-acetylmuramoylalanine--D-glu...759.4     32.3     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008764; F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
87A8Z3M4    449   MURD_STAAT UDP-N-acetylmuramoylalanine--D-glu...759.4     32.3     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008764; F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
88P0A090    449   MURD_STAAN UDP-N-acetylmuramoylalanine--D-glu...759.4     32.3     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008764; F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
89P0A089    449   MURD_STAAM UDP-N-acetylmuramoylalanine--D-glu...759.4     32.3     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008764; F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
90A6QG83    449   MURD_STAAE UDP-N-acetylmuramoylalanine--D-glu...759.4     32.3     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008764; F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
91Q5HGP8    449   MURD_STAAC UDP-N-acetylmuramoylalanine--D-glu...759.4     32.3     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008764; F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
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