Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR165C
Length:
2413
Number of sequences:
5887
Description:
YHR165C PRP8 SGDID:S000001208, Chr VIII from 436948-429707, Genome Release 64-1-1, reverse complement, Verified ORF, "Component of the U4/U6-U5 snRNP complex, involved in the second catalytic step of splicing; mutations of human Prp8 cause retinitis pigmentosa"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P33334    2413   PRP8_YEAST Pre-mRNA-splicing factor 8 OS=Sacc...24130     4997     100     100GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD.::GO:0005682; C:U5 snRNP; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0030623; F:U5 snRNA binding; IDA:SGD.
GO:0000244; P:assembly of spliceosomal tri-snRNP; IMP:SGD.::GO:0000389; P:nuclear mRNA 3'-splice site recognition; IMP:SGD.
2O14187    2363   SPP42_SCHPO Pre-mRNA-splicing factor spp42 OS...23240     3046     62     79GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:PomBase.::GO:0005682; C:U5 snRNP; ISS:PomBase.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000393; P:spliceosomal conformational changes to generate catalytic conformation; IGI:PomBase.
3Q6P2Q9    2335   PRP8_HUMAN Pre-mRNA-processing-splicing facto...23210     3036     63     78GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005682; C:U5 snRNP; TAS:ProtInc.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.
4Q99PV0    2335   PRP8_MOUSE Pre-mRNA-processing-splicing facto...23190     3033     62     78GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IEA:InterPro.
5P34369    2329   PRP8_CAEEL Pre-mRNA-splicing factor 8 homolog...23320     2950     61     77GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0016477; P:cell migration; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IEA:InterPro.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
6Q8T295    2327   PRP8_DICDI Pre-mRNA-processing-splicing facto...23150     2912     60     77GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0005682; C:U5 snRNP; ISS:dictyBase.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IEA:InterPro.
7Q9CQ26    424   STABP_MOUSE STAM-binding protein OS=Mus muscu...1740.001     47.4     25     41GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:MGI.
8Q8R424    424   STABP_RAT STAM-binding protein OS=Rattus norv...1740.001     47.4     25     41GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
9Q5R558    436   STALP_PONAB AMSH-like protease OS=Pongo abeli...1800.004     45.8     23     42
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
10Q76N33    436   STALP_MOUSE AMSH-like protease OS=Mus musculu...1800.007     45.1     23     42
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
11Q63ZM7    416   STABP_XENLA STAM-binding protein-like OS=Xeno...1480.025     43.1     24     43
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
12Q96FJ0    436   STALP_HUMAN AMSH-like protease OS=Homo sapien...1800.038     42.7     23     42
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
13O95630    424   STABP_HUMAN STAM-binding protein OS=Homo sapi...1690.18     40.4     22     41GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
14Q6TH47    418   STBPA_DANRE STAM-binding protein-like A OS=Da...1480.3     39.7     24     39
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
15A3CS68    192   VATE_METMJ V-type ATP synthase subunit E OS=M...800.49     38.1     31     55GO:0033178; C:proton-transporting two-sector ATPase complex, catalytic domain; IEA:InterPro.
GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
GO:0006754; P:ATP biosynthetic process; IEA:UniProtKB-KW.::GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
16Q8VYB5    507   AMSH1_ARATH AMSH-like ubiquitin thioesterase ...561.4     37.7     36     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
17Q8NCA9    323   ZN784_HUMAN Zinc finger protein 784 OS=Homo s...561.7     37     36     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18Q84WF0    487   SCP37_ARATH Serine carboxypeptidase-like 37 O...1113.1     36.6     29     44GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004185; F:serine-type carboxypeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
19Q39Y12    1392   RPOC_GEOMG DNA-directed RNA polymerase subuni...2463.8     36.6     26     40
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
20Q5PNU3    507   AMSH3_ARATH AMSH-like ubiquitin thioesterase ...614.6     36.2     33     52GO:0016021; C:integral to membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006897; P:endocytosis; IMP:TAIR.::GO:0046907; P:intracellular transport; IMP:TAIR.::GO:0090316; P:positive regulation of intracellular protein transport; IMP:UniProtKB.::GO:0044090; P:positive regulation of vacuole organization; IMP:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007033; P:vacuole organization; IMP:TAIR.
21Q5WDI1    240   HIS4_BACSK 1-(5-phosphoribosyl)-5-[(5-phospho...1197.1     34.7     29     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003949; F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneaminoimidazole-4-carboxamide isomerase activity; IEA:EC.
GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.]
22Q7VRM7    314   CORA_BLOFL Magnesium transport protein CorA O...1338.2     35     28     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:InterPro.::GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
23Q59019    765   Y1626_METJA Uncharacterized protein MJ1626 OS...638.6     35.4     30     51
24Q5ZLR5    272   UCRI_CHICK Cytochrome b-c1 complex subunit Ri...1729.6     34.7     22     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008121; F:ubiquinol-cytochrome-c reductase activity; IEA:EC.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
records
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