Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR135C
Length:
538
Number of sequences:
5887
Description:
YHR135C YCK1 SGDID:S000001177, Chr VIII from 374310-372694, Genome Release 64-1-1, reverse complement, Verified ORF, "Palmitoylated plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck2p in morphogenesis, proper septin assembly, endocytic trafficking; provides an essential function overlapping with that of Yck2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
781B0VXE8    423   CDK14_CALJA Cyclin-dependent kinase 14 OS=Cal...2140.00005     49.7     24     41GO:0000308; C:cytoplasmic cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0060828; P:regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
782P23111    294   CDC2_MAIZE Cell division control protein 2 ho...2030.00005     48.9     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0007067; P:mitosis; IEA:UniProtKB-KW.
783Q9NQU5    681   PAK6_HUMAN Serine/threonine-protein kinase PA...2110.00005     50.1     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:UniProtKB.
784Q754N7    719   CBK1_ASHGO Serine/threonine-protein kinase CB...1540.00005     50.1     30     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
785B6A7Q3    468   CDK14_RABIT Cyclin-dependent kinase 14 OS=Ory...2140.00005     49.7     24     42GO:0000308; C:cytoplasmic cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0060828; P:regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
786Q55CA6    635   Y0146_DICDI Probable serine/threonine-protein...2080.00005     49.7     25     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
787P14680    807   YAK1_YEAST Dual specificity protein kinase YA...1840.00005     50.1     26     46GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IDA:SGD.
788Q68Y49    508   CIPKJ_ORYSJ CBL-interacting protein kinase 19...2160.00005     49.7     22     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
789Q9HBY8    427   SGK2_HUMAN Serine/threonine-protein kinase Sg...1550.00005     49.7     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015459; F:potassium channel regulator activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0017080; F:sodium channel regulator activity; NAS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0032411; P:positive regulation of transporter activity; TAS:UniProtKB.::GO:0001558; P:regulation of cell growth; TAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:0006979; P:response to oxidative stress; TAS:ProtInc.
790P54646    552   AAPK2_HUMAN 5'-AMP-activated protein kinase c...2280.00005     49.7     23     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0006853; P:carnitine shuttle; TAS:Reactome.::GO:0007050; P:cell cycle arrest; TAS:Reactome.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0042304; P:regulation of fatty acid biosynthetic process; TAS:Reactome.::GO:0046320; P:regulation of fatty acid oxidation; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
791Q10056    589   SHK2_SCHPO Serine/threonine-protein kinase sh...2180.00005     49.7     22     44GO:0005739; C:mitochondrion; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0032488; P:Cdc42 protein signal transduction; NAS:PomBase.::GO:0000165; P:MAPK cascade; NAS:PomBase.
792P97711    576   GRK6_RAT G protein-coupled receptor kinase 6 ...1320.00005     49.7     26     44GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IDA:RGD.
GO:0002029; P:desensitization of G-protein coupled receptor protein signaling pathway; IDA:RGD.::GO:0010360; P:negative regulation of anion channel activity; IMP:RGD.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
793Q8IVW4    592   CDKL3_HUMAN Cyclin-dependent kinase-like 3 OS...1650.00005     49.7     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
794P67998    525   KS6B1_RABIT Ribosomal protein S6 kinase beta-...1120.00005     49.7     29     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071363; P:cellular response to growth factor stimulus; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.
795Q7SY52    974   STK10_DANRE Serine/threonine-protein kinase 1...1810.00005     50.1     25     48GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
796Q6TJY3    527   KS6B1_BOVIN Ribosomal protein S6 kinase beta-...1120.00005     49.7     29     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071363; P:cellular response to growth factor stimulus; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
797O77708    533   KCC2D_RABIT Calcium/calmodulin-dependent prot...2140.00005     49.7     24     43GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0060341; P:regulation of cellular localization; ISS:UniProtKB.
798Q54IF2    641   Y0670_DICDI Probable serine/threonine-protein...1160.00005     49.7     30     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
799Q8BSK8    525   KS6B1_MOUSE Ribosomal protein S6 kinase beta-...1120.00005     49.7     29     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071363; P:cellular response to growth factor stimulus; ISS:UniProtKB.::GO:0007281; P:germ cell development; IDA:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
800P23443    525   KS6B1_HUMAN Ribosomal protein S6 kinase beta-...1120.00005     49.7     29     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004672; F:protein kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071363; P:cellular response to growth factor stimulus; IDA:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; IMP:UniProtKB.::GO:0031929; P:TOR signaling cascade; IDA:UniProtKB.
801P41279    467   M3K8_HUMAN Mitogen-activated protein kinase k...1320.00005     49.7     28     46GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:InterPro.::GO:0031295; P:T cell costimulation; TAS:Reactome.
802Q9Z2G7    548   GRK7_SPETR G protein-coupled receptor kinase ...1670.00005     49.7     26     46GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.::GO:0050254; F:rhodopsin kinase activity; ISS:UniProtKB.
GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
803Q3UTQ8    938   CDKL5_MOUSE Cyclin-dependent kinase-like 5 OS...2010.00005     50.1     23     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
804Q13188    491   STK3_HUMAN Serine/threonine-protein kinase 3 ...1780.00005     49.7     25     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0046983; F:protein dimerization activity; ISS:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; IDA:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0035329; P:hippo signaling cascade; TAS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
805Q38HL5    366   HOG1_EURHE Mitogen-activated protein kinase h...1790.00005     49.3     25     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
806Q00535    292   CDK5_HUMAN Cyclin-dependent kinase 5 OS=Homo ...2030.00005     48.9     26     42GO:0030424; C:axon; ISS:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0031594; C:neuromuscular junction; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0030549; F:acetylcholine receptor activator activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; ISS:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0008633; P:activation of pro-apoptotic gene products; IDA:UniProtKB.::GO:0048675; P:axon extension; TAS:UniProtKB.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:DFLAT.::GO:0051402; P:neuron apoptotic process; TAS:UniProtKB.::GO:0001764; P:neuron migration; TAS:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; IDA:UniProtKB.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; TAS:UniProtKB.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0071156; P:regulation of cell cycle arrest; TAS:UniProtKB.::GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0007416; P:synapse assembly; TAS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; TAS:UniProtKB.::GO:0016079; P:synaptic vesicle exocytosis; TAS:UniProtKB.
807Q12852    859   M3K12_HUMAN Mitogen-activated protein kinase ...1200.00005     49.7     26     46GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0016572; P:histone phosphorylation; ISS:UniProtKB.::GO:0007254; P:JNK cascade; ISS:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
808P49615    292   CDK5_MOUSE Cyclin-dependent kinase 5 OS=Mus m...2030.00005     48.9     26     42GO:0030424; C:axon; ISS:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:MGI.::GO:0030175; C:filopodium; IDA:MGI.::GO:0030426; C:growth cone; ISS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0031594; C:neuromuscular junction; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0030549; F:acetylcholine receptor activator activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; IDA:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IPI:MGI.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0048148; P:behavioral response to cocaine; IMP:MGI.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007160; P:cell-matrix adhesion; IDA:MGI.::GO:0021954; P:central nervous system neuron development; IMP:MGI.::GO:0021697; P:cerebellar cortex formation; IMP:MGI.::GO:0022038; P:corpus callosum development; IMP:MGI.::GO:0048813; P:dendrite morphogenesis; IMP:MGI.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0021766; P:hippocampus development; IMP:MGI.::GO:0006886; P:intracellular protein transport; IMP:MGI.::GO:0021819; P:layer formation in cerebral cortex; IMP:MGI.::GO:0008045; P:motor axon guidance; IMP:MGI.::GO:0045786; P:negative regulation of cell cycle; IMP:MGI.::GO:0046826; P:negative regulation of protein export from nucleus; IMP:MGI.::GO:0031397; P:negative regulation of protein ubiquitination; IMP:MGI.::GO:0031914; P:negative regulation of synaptic plasticity; IMP:MGI.::GO:0051402; P:neuron apoptotic process; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IDA:MGI.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; IMP:MGI.::GO:0032801; P:receptor catabolic process; IMP:MGI.::GO:0043113; P:receptor clustering; IMP:MGI.::GO:0030334; P:regulation of cell migration; IMP:MGI.::GO:0061001; P:regulation of dendritic spine morphogenesis; IMP:UniProtKB.::GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IMP:MGI.::GO:0014044; P:Schwann cell development; IMP:MGI.::GO:0019233; P:sensory perception of pain; IMP:MGI.::GO:0033136; P:serine phosphorylation of STAT3 protein; IDA:MGI.::GO:0007519; P:skeletal muscle tissue development; IDA:MGI.::GO:0001963; P:synaptic transmission, dopaminergic; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0008542; P:visual learning; IMP:MGI.
809Q02399    292   CDK5_BOVIN Cyclin-dependent kinase 5 OS=Bos t...2030.00005     48.9     26     42GO:0030424; C:axon; ISS:AgBase.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:AgBase.::GO:0030175; C:filopodium; ISS:AgBase.::GO:0030426; C:growth cone; ISS:AgBase.::GO:0030027; C:lamellipodium; ISS:AgBase.::GO:0031594; C:neuromuscular junction; ISS:AgBase.::GO:0005634; C:nucleus; ISS:AgBase.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0030549; F:acetylcholine receptor activator activity; ISS:AgBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005176; F:ErbB-2 class receptor binding; ISS:AgBase.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0035173; F:histone kinase activity; TAS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:AgBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007160; P:cell-matrix adhesion; ISS:AgBase.::GO:0009790; P:embryo development; ISS:AgBase.::GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:AgBase.::GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.
810P67999    525   KS6B1_RAT Ribosomal protein S6 kinase beta-1 ...1120.00005     49.7     29     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; IDA:RGD.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0042277; F:peptide binding; IDA:RGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004711; F:ribosomal protein S6 kinase activity; IMP:RGD.
GO:0007568; P:aging; IEP:RGD.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IEP:RGD.::GO:0071363; P:cellular response to growth factor stimulus; ISS:UniProtKB.::GO:0032870; P:cellular response to hormone stimulus; IEP:RGD.::GO:0007616; P:long-term memory; IEP:RGD.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:UniProtKB.::GO:0048633; P:positive regulation of skeletal muscle tissue growth; IMP:RGD.::GO:0014911; P:positive regulation of smooth muscle cell migration; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0046324; P:regulation of glucose import; IMP:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0014878; P:response to electrical stimulus involved in regulation of muscle adaptation; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0033762; P:response to glucagon stimulus; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009408; P:response to heat; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IMP:UniProtKB.::GO:0043201; P:response to leucine; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.::GO:0034612; P:response to tumor necrosis factor; IMP:UniProtKB.::GO:0009611; P:response to wounding; IEP:RGD.::GO:0014732; P:skeletal muscle atrophy; IEP:RGD.::GO:0003009; P:skeletal muscle contraction; IEP:RGD.
811O94921    469   CDK14_HUMAN Cyclin-dependent kinase 14 OS=Hom...2140.00005     49.3     24     41GO:0000308; C:cytoplasmic cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IMP:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:UniProtKB.::GO:0060828; P:regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
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