Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR133C
Length:
291
Number of sequences:
5887
Description:
YHR133C NSG1 SGDID:S000001175, Chr VIII from 371597-370722, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38837    291   NSG1_YEAST Protein NSG1 OS=Saccharomyces cere...2910     593     100     100GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0051082; F:unfolded protein binding; IMP:SGD.
GO:0016126; P:sterol biosynthetic process; IMP:SGD.
2P53898    299   NSG2_YEAST Protein NSG2 OS=Saccharomyces cere...2933e-49     171     35     55GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0051082; F:unfolded protein binding; IMP:SGD.
GO:0016126; P:sterol biosynthetic process; IGI:SGD.
3Q6PQZ3    225   INSI2_PIG Insulin-induced gene 2 protein OS=S...1230.54     35     24     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
4A9RA88    225   INSI2_PAPAN Insulin-induced gene 2 protein OS...1230.56     34.7     24     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
5Q5R687    238   INSI2_PONAB Insulin-induced gene 2 protein OS...1200.59     34.7     24     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
6Q9Y5U4    225   INSI2_HUMAN Insulin-induced gene 2 protein OS...1200.68     34.7     24     45GO:0032937; C:SREBP-SCAP-Insig complex; IDA:UniProtKB.
GO:0030967; P:ER-nuclear sterol response pathway; IDA:UniProtKB.
7Q91WG1    225   INSI2_MOUSE Insulin-induced gene 2 protein OS...1801.3     33.9     21     41
GO:0006695; P:cholesterol biosynthetic process; IGI:MGI.::GO:0060363; P:cranial suture morphogenesis; IGI:MGI.::GO:0042472; P:inner ear morphogenesis; IGI:MGI.::GO:0042474; P:middle ear morphogenesis; IGI:MGI.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; IGI:MGI.::GO:0010894; P:negative regulation of steroid biosynthetic process; IGI:MGI.::GO:0060021; P:palate development; IGI:MGI.::GO:0006641; P:triglyceride metabolic process; IGI:MGI.
8A0JNC3    276   INSI1_BOVIN Insulin-induced gene 1 protein OS...971.4     33.9     25     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
9O15503    277   INSI1_HUMAN Insulin-induced gene 1 protein OS...951.4     33.9     25     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0030967; P:ER-nuclear sterol response pathway; IDA:UniProtKB.
10Q80UA9    225   INSI2_RAT Insulin-induced gene 2 protein OS=R...1801.7     33.5     21     41
GO:0008134; F:transcription factor binding; IDA:RGD.
GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.
11B0CMA4    225   INSI2_CALJA Insulin-induced gene 2 protein OS...1201.9     33.1     24     46
12Q8BGI3    259   INSI1_MOUSE Insulin-induced gene 1 protein OS...972     33.1     27     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:MGI.
GO:0006695; P:cholesterol biosynthetic process; IGI:MGI.::GO:0060363; P:cranial suture morphogenesis; IGI:MGI.::GO:0042472; P:inner ear morphogenesis; IGI:MGI.::GO:0042474; P:middle ear morphogenesis; IGI:MGI.::GO:0045599; P:negative regulation of fat cell differentiation; IDA:MGI.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; IGI:MGI.::GO:0010894; P:negative regulation of steroid biosynthetic process; IGI:MGI.::GO:0060021; P:palate development; IGI:MGI.::GO:0006641; P:triglyceride metabolic process; IGI:MGI.
13Q8CFA6    257   INSI1_CRIGR Insulin-induced gene 1 protein OS...952.3     33.1     25     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
14Q5ZMT9    252   INSI1_CHICK Insulin-induced gene 1 protein OS...1392.4     33.1     24     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
15Q08755    259   INSI1_RAT Insulin-induced gene 1 protein OS=R...952.7     32.7     25     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.
16Q66J27    218   INSI2_XENLA Insulin-induced gene 2 protein OS...792.9     32.7     25     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
17Q0V9G6    251   INSI1_XENTR Insulin-induced gene 1 protein OS...1163.7     32.3     24     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
18Q6DF80    251   INSI1_XENLA Insulin-induced gene 1 protein OS...974.3     32.3     25     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
19Q5U4Q2    218   INSI2_XENTR Insulin-induced gene 2 protein OS...795.7     31.6     25     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
20Q8AV61    251   INSI1_DANRE Insulin-induced gene 1 protein OS...1256.8     31.6     22     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
records
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