Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR119W
Length:
1080
Number of sequences:
5887
Description:
YHR119W SET1 SGDID:S000001161, Chr VIII from 346043-349285, Genome Release 64-1-1, Verified ORF, "Histone methyltransferase, subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3K4; Set1p-dependent H3K4 trimethylation recruits Nrd1p, allowing efficient termination of snoRNAs and cryptic unstable transcripts (CUTs) by Nrd1p-Nab3p-Sen1p pathway; modulates histone acetylation levels in promoter proximal regions to ensure efficient Nrd1p-dependent termination; required in transcriptional silencing near telomeres and at silent mating type loci; has a SET domain"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q6C5G5    768   SET2_YARLI Histone-lysine N-methyltransferase...1329e-22     105     42     52GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
62Q4IB50    1051   SET2_GIBZE Histone-lysine N-methyltransferase...1521e-21     105     36     53GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
63O96028    1365   NSD2_HUMAN Probable histone-lysine N-methyltr...2251e-21     105     31     45GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
64Q8BVE8    1365   NSD2_MOUSE Probable histone-lysine N-methyltr...2251e-21     105     31     45GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0003289; P:atrial septum primum morphogenesis; IMP:MGI.::GO:0003290; P:atrial septum secundum morphogenesis; IMP:MGI.::GO:0060348; P:bone development; IMP:MGI.::GO:0003149; P:membranous septum morphogenesis; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
65Q2LAE1    1759   ASHH2_ARATH Histone-lysine N-methyltransferas...1554e-21     103     35     54GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048653; P:anther development; IMP:TAIR.::GO:0016116; P:carotenoid metabolic process; IMP:TAIR.::GO:0009553; P:embryo sac development; IMP:TAIR.::GO:0010452; P:histone H3-K36 methylation; IDA:TAIR.::GO:0009910; P:negative regulation of flower development; IMP:TAIR.::GO:0048481; P:ovule development; IMP:TAIR.::GO:0009555; P:pollen development; IMP:TAIR.::GO:0031062; P:positive regulation of histone methylation; IDA:TAIR.::GO:0040029; P:regulation of gene expression, epigenetic; IMP:TAIR.::GO:0010363; P:regulation of plant-type hypersensitive response; IMP:TAIR.::GO:0010223; P:secondary shoot formation; IMP:TAIR.
66A7E2Z2    747   EZH1_BOVIN Histone-lysine N-methyltransferase...1229e-21     102     43     61GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
67P70351    747   EZH1_MOUSE Histone-lysine N-methyltransferase...1209e-21     102     44     61GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046976; F:histone methyltransferase activity (H3-K27 specific); IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
68Q92800    747   EZH1_HUMAN Histone-lysine N-methyltransferase...1201e-20     102     44     61GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; TAS:ProtInc.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
69Q5RDS6    747   EZH1_PONAB Histone-lysine N-methyltransferase...1203e-20     100     44     60GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
70Q4V863    748   EZH2B_XENLA Histone-lysine N-methyltransferas...1205e-20     99.8     43     59GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
71Q98SM3    748   EZH2A_XENLA Histone-lysine N-methyltransferas...1205e-20     99.8     43     60GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
72O14026    798   SET2_SCHPO Histone-lysine N-methyltransferase...1306e-20     99.4     38     53GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:PomBase.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IC:PomBase.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IGI:PomBase.
73Q15910    746   EZH2_HUMAN Histone-lysine N-methyltransferase...1207e-20     99.4     43     59GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
74Q4R381    746   EZH2_MACFA Histone-lysine N-methyltransferase...1208e-20     99     43     59GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
75Q61188    746   EZH2_MOUSE Histone-lysine N-methyltransferase...1208e-20     99     43     59GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0035098; C:ESC/E(Z) complex; IDA:UniProtKB.::GO:0045120; C:pronucleus; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0001047; F:core promoter binding; IDA:MGI.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
GO:0021695; P:cerebellar cortex development; IMP:MGI.::GO:0070314; P:G1 to G0 transition; IMP:MGI.::GO:0070734; P:histone H3-K27 methylation; IMP:MGI.::GO:0045605; P:negative regulation of epidermal cell differentiation; IMP:MGI.::GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:0051154; P:negative regulation of striated muscle cell differentiation; IDA:MGI.::GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IMP:MGI.::GO:0014013; P:regulation of gliogenesis; IMP:MGI.::GO:0001932; P:regulation of protein phosphorylation; IMP:MGI.::GO:0000084; P:S phase of mitotic cell cycle; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
76Q28D84    748   EZH2_XENTR Histone-lysine N-methyltransferase...1209e-20     99     43     59GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
77Q99MY8    2958   ASH1L_MOUSE Histone-lysine N-methyltransferas...1381e-19     99.4     37     54GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
78Q9NR48    2969   ASH1L_HUMAN Histone-lysine N-methyltransferas...1381e-19     99.4     37     54GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005923; C:tight junction; TAS:ProtInc.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0006323; P:DNA packaging; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
79Q59XV0    844   SET2_CANAL Histone-lysine N-methyltransferase...1462e-19     98.2     35     51GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
80Q9VYD1    2313   C1716_DROME Probable histone-lysine N-methylt...1422e-19     98.2     37     52GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:FlyBase.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IMP:FlyBase.::GO:0051219; F:phosphoprotein binding; IPI:FlyBase.
GO:0035076; P:ecdysone receptor-mediated signaling pathway; IGI:FlyBase.::GO:0002168; P:instar larval development; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase.
81Q08BS4    760   EZH2_DANRE Histone-lysine N-methyltransferase...1203e-19     97.1     42     59GO:0035098; C:ESC/E(Z) complex; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
82O65312    689   MEDEA_ARATH Histone-lysine N-methyltransferas...1333e-19     97.1     38     57GO:0005634; C:nucleus; IDA:TAIR.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IDA:TAIR.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:TAIR.::GO:2000014; P:regulation of endosperm development; IMP:TAIR.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:TAIR.::GO:0009646; P:response to absence of light; IEP:TAIR.::GO:0048317; P:seed morphogenesis; IGI:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
83Q945S8    363   ASHH3_ARATH Histone-lysine N-methyltransferas...1266e-19     93.6     41     55GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
84Q8S4P6    931   EZ1_MAIZE Histone-lysine N-methyltransferase ...1397e-19     96.3     37     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
85P42124    760   EZ_DROME Histone-lysine N-methyltransferase E...1194e-18     93.6     42     58GO:0035098; C:ESC/E(Z) complex; IDA:FlyBase.::GO:0000790; C:nuclear chromatin; NAS:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0046976; F:histone methyltransferase activity (H3-K27 specific); IDA:FlyBase.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IDA:FlyBase.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0006723; P:cuticle hydrocarbon biosynthetic process; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0016458; P:gene silencing; NAS:UniProtKB.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0035186; P:syncytial blastoderm mitotic cell cycle; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
86Q757Y8    684   SET2_ASHGO Histone-lysine N-methyltransferase...1856e-18     92.8     31     44GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
87P93831    902   CLF_ARATH Histone-lysine N-methyltransferase ...1397e-18     93.2     36     57GO:0005634; C:nucleus; IDA:TAIR.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003727; F:single-stranded RNA binding; IDA:TAIR.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009294; P:DNA mediated transformation; IMP:TAIR.::GO:0009908; P:flower development; IEA:UniProtKB-KW.::GO:0009965; P:leaf morphogenesis; IMP:TAIR.::GO:0045857; P:negative regulation of molecular function, epigenetic; IMP:TAIR.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR.
88Q9VW15    2226   ASH1_DROME Histone-lysine N-methyltransferase...1367e-18     93.6     36     49GO:0005634; C:nucleus; IC:FlyBase.::GO:0035327; C:transcriptionally active chromatin; IMP:FlyBase.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:FlyBase.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); NAS:FlyBase.::GO:0042799; F:histone methyltransferase activity (H4-K20 specific); NAS:FlyBase.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003727; F:single-stranded RNA binding; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048096; P:chromatin-mediated maintenance of transcription; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase.::GO:0018991; P:oviposition; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
89Q6CXP5    702   SET2_KLULA Histone-lysine N-methyltransferase...1308e-18     92.4     38     52GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
90Q6BM04    731   SET2_DEBHA Histone-lysine N-methyltransferase...1401e-17     92     34     52GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
91Q9M1X9    352   ASHH4_ARATH Putative histone-lysine N-methylt...1271e-17     89.4     40     57GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.
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