UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YHR115C

Length:

416

Number of sequences:

5887

Description:

YHR115C DMA1 SGDID:S000001157, Chr VIII from 341359-340109, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in ubiquitin ligation; plays a role in regulating spindle position and orientation; functionally redundant with Dma2p; orthologous to human RNF8 protein, also has sequence similarity to human Chfr."

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P38823	416	DMA1_YEAST E3 ubiquitin-protein ligase DMA1 O...	416	0	864	100	100	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000132; P:establishment of mitotic spindle orientation; IGI:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IGI:SGD.::GO:0051865; P:protein autoubiquitination; IDA:SGD.::GO:0000921; P:septin ring assembly; IGI:SGD.
2	A6ZRW7	522	DMA2_YEAS7 E3 ubiquitin-protein ligase DMA2 O...	375	1e-156	459	63	75	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
3	P53924	522	DMA2_YEAST E3 ubiquitin-protein ligase DMA2 O...	375	2e-156	459	63	75	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000132; P:establishment of mitotic spindle orientation; IGI:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IGI:SGD.::GO:0051865; P:protein autoubiquitination; IDA:SGD.::GO:0000921; P:septin ring assembly; IGI:SGD.
4	Q10322	267	DMA1_SCHPO Probable E3 ubiquitin-protein liga...	239	1e-52	182	42	59	GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-KW.::GO:0005816; C:spindle pole body; IDA:PomBase.
									GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:PomBase.::GO:0031030; P:negative regulation of septation initiation signaling cascade; TAS:PomBase.
5	Q28623	771	SLMAP_RABIT Sarcolemmal membrane-associated p...	107	0.00000001	60.8	38	52	GO:0005615; C:extracellular space; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016272; C:prefoldin complex; IEA:InterPro.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
									GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006457; P:protein folding; IEA:InterPro.
6	Q14BN4	828	SLMAP_HUMAN Sarcolemmal membrane-associated p...	107	0.00000001	60.8	38	52	GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016272; C:prefoldin complex; IEA:InterPro.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.::GO:0005790; C:smooth endoplasmic reticulum; TAS:ProtInc.
									GO:0051082; F:unfolded protein binding; IEA:InterPro.
									GO:0006936; P:muscle contraction; TAS:ProtInc.::GO:0006457; P:protein folding; IEA:InterPro.
7	Q3URD3	845	SLMAP_MOUSE Sarcolemmal membrane-associated p...	107	0.00000009	57.8	37	51	GO:0005615; C:extracellular space; IEA:InterPro.::GO:0016021; C:integral to membrane; IDA:MGI.::GO:0031430; C:M band; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
									GO:0005515; F:protein binding; IPI:IntAct.
8	P0C219	858	SLMAP_RAT Sarcolemmal membrane-associated pro...	108	0.0000001	57.4	37	51	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
9	O74388	301	YNVD_SCHPO Uncharacterized protein C3H7.13 OS...	104	0.0000002	55.8	35	56	GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005783; C:endoplasmic reticulum; ISS:PomBase.::GO:0016020; C:membrane; NAS:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005816; C:spindle pole body; IDA:PomBase.
10	Q8VC56	488	RNF8_MOUSE E3 ubiquitin-protein ligase RNF8 O...	90	0.00002	50.4	34	54	GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; IMP:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; IMP:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
11	Q2HJ46	487	RNF8_BOVIN E3 ubiquitin-protein ligase RNF8 O...	89	0.00002	50.4	36	54	GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
12	Q4KLN8	487	RNF8_RAT E3 ubiquitin-protein ligase RNF8 OS=...	90	0.00003	49.7	36	53	GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
13	Q5R4I2	486	RNF8_PONAB E3 ubiquitin-protein ligase RNF8 O...	89	0.00006	48.5	35	51	GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
14	Q06001	478	FAR10_YEAST Factor arrest protein 10 OS=Sacch...	64	0.00007	48.5	41	58	GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
15	O76064	485	RNF8_HUMAN E3 ubiquitin-protein ligase RNF8 O...	89	0.0002	47	34	49	GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
									GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; IDA:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; IDA:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB.::GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
16	Q03944	604	VPS64_YEAST Vacuolar protein sorting-associat...	80	0.0003	46.6	34	51	GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006623; P:protein targeting to vacuole; IMP:SGD.
17	Q91XF4	347	RN167_MOUSE E3 ubiquitin-protein ligase RNF16...	110	0.0007	45.1	28	46	GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0008270; F:zinc ion binding; IEA:InterPro.
18	Q5XIL0	349	RN167_RAT E3 ubiquitin-protein ligase RNF167 ...	110	0.0008	45.1	29	46	GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0008270; F:zinc ion binding; IEA:InterPro.
19	Q7ZX20	540	RNF8A_XENLA E3 ubiquitin-protein ligase RNF8-...	57	0.001	45.1	42	58	GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:InterPro.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
20	Q5SSZ7	913	ZNRF3_MOUSE Zinc/RING finger protein 3 OS=Mus...	80	0.002	43.9	30	51	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0008270; F:zinc ion binding; IEA:InterPro.
21	Q8RXX9	398	ATL6_ARATH E3 ubiquitin-protein ligase ATL6 O...	86	0.004	42.7	31	48	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
									GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0010200; P:response to chitin; IEP:TAIR.
22	Q6NRG0	532	RNF8B_XENLA E3 ubiquitin-protein ligase RNF8-...	57	0.005	42.7	40	58	GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0051301; P:cell division; IEA:InterPro.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
23	Q9SL78	390	ATL12_ARATH Putative RING-H2 finger protein A...	112	0.006	42.4	29	47	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0008270; F:zinc ion binding; IEA:InterPro.
24	Q9H6Y7	350	RN167_HUMAN E3 ubiquitin-protein ligase RNF16...	93	0.007	42	27	46	GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0045786; P:negative regulation of cell cycle; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
25	Q66J97	967	R111C_XENLA E3 ubiquitin-protein ligase arkad...	115	0.008	42.4	29	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
26	Q641J8	622	RF12A_XENLA E3 ubiquitin-protein ligase RNF12...	45	0.009	42	33	51	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000578; P:embryonic axis specification; IMP:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
27	Q7X843	349	ATL48_ARATH RING-H2 finger protein ATL48 OS=A...	71	0.009	41.6	31	52	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0008270; F:zinc ion binding; IEA:InterPro.
28	Q90ZT7	923	R111A_XENLA E3 ubiquitin-protein ligase arkad...	115	0.009	42	29	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
29	Q7T037	757	RF12B_XENLA E3 ubiquitin-protein ligase RNF12...	45	0.009	42	33	51	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0000578; P:embryonic axis specification; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
30	Q0V9R0	954	RN111_XENTR E3 ubiquitin-protein ligase arkad...	115	0.009	42	30	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
31	Q6NRV8	959	R111B_XENLA E3 ubiquitin-protein ligase arkad...	115	0.01	42	30	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.

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