rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q5ZLR6 | 764 | ARHG6_CHICK Rho guanine nucleotide exchange f... | 53 | 0.009 | 42.7 | 36 | 64 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 92 | Q6NRD3 | 826 | SH3R1_XENLA E3 ubiquitin-protein ligase SH3RF... | 61 | 0.003 | 44.7 | 34 | 56 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 93 | Q28E95 | 861 | SH3R1_XENTR E3 ubiquitin-protein ligase SH3RF... | 61 | 0.003 | 44.7 | 34 | 56 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 94 | A4FU49 | 640 | SH321_HUMAN SH3 domain-containing protein 21 ... | 49 | 0.003 | 44.3 | 31 | 63 | | | | | | | | | | | | | | | | | | | | | | 95 | O43586 | 416 | PPIP1_HUMAN Proline-serine-threonine phosphat... | 169 | 5.1 | 33.9 | 18 | 46 | GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome. | 96 | P62484 | 446 | ABI2_MOUSE Abl interactor 2 OS=Mus musculus (... | 50 | 0.003 | 44.3 | 44 | 60 | GO:0005913; C:cell-cell adherens junction; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IDA:MGI.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0016358; P:dendrite development; IMP:MGI.::GO:0007611; P:learning or memory; IMP:MGI. | 97 | O76041 | 1014 | NEBL_HUMAN Nebulette OS=Homo sapiens (Human).... | 64 | 0.22 | 38.5 | 31 | 52 | GO:0001725; C:stress fiber; IDA:UniProtKB.::GO:0030018; C:Z disc; IDA:UniProtKB. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0031005; F:filamin binding; IPI:UniProtKB.::GO:0008307; F:structural constituent of muscle; NAS:UniProtKB.::GO:0005523; F:tropomyosin binding; IPI:UniProtKB. | | | | | | | | | | GO:0071691; P:cardiac muscle thin filament assembly; IMP:UniProtKB. | 98 | A1IGU3 | 676 | ARH37_RAT Rho guanine nucleotide exchange fac... | 137 | 0.003 | 44.3 | 25 | 45 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 99 | Q06449 | 215 | PIN3_YEAST [PSI+] inducibility protein 3 OS=S... | 75 | 0.34 | 37 | 27 | 51 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IPI:SGD. | 100 | P97814 | 415 | PPIP1_MOUSE Proline-serine-threonine phosphat... | 52 | 0.6 | 36.6 | 31 | 54 | GO:0005826; C:actomyosin contractile ring; IDA:MGI.::GO:0032154; C:cleavage furrow; IDA:MGI.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IDA:MGI.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0019903; F:protein phosphatase binding; IDA:MGI. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IC:MGI. | 101 | Q8BGG7 | 638 | UBS3B_MOUSE Ubiquitin-associated and SH3 doma... | 56 | 0.012 | 42.4 | 39 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 102 | P27870 | 845 | VAV_MOUSE Proto-oncogene vav OS=Mus musculus ... | 61 | 0.004 | 44.3 | 38 | 52 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IGI:MGI. | | | | | | | | | | GO:0006955; P:immune response; IMP:MGI.::GO:0007229; P:integrin-mediated signaling pathway; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0006909; P:phagocytosis; IGI:MGI.::GO:0045785; P:positive regulation of cell adhesion; IGI:MGI.::GO:0043087; P:regulation of GTPase activity; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0030217; P:T cell differentiation; TAS:MGI. | 103 | Q8VDG6 | 1002 | M3KL4_MOUSE Mitogen-activated protein kinase ... | 52 | 0.004 | 43.9 | 38 | 58 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 104 | Q9NYB9 | 513 | ABI2_HUMAN Abl interactor 2 OS=Homo sapiens (... | 50 | 0.004 | 43.5 | 44 | 60 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; TAS:UniProtKB.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0019900; F:kinase binding; NAS:UniProtKB.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0008154; P:actin polymerization or depolymerization; NAS:UniProtKB.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI. | 105 | Q9XVN3 | 769 | IASPP_CAEEL Apoptotic enhancer 1 protein OS=C... | 59 | 4.9 | 33.9 | 32 | 54 | GO:0005634; C:nucleus; ISS:WormBase. | | | | | | | | | | GO:0002039; F:p53 binding; IPI:WormBase. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:WormBase. | 106 | Q6ZQ82 | 814 | RHG26_MOUSE Rho GTPase-activating protein 26 ... | 54 | 3.7 | 34.3 | 33 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 107 | Q6P686 | 214 | OSTF1_RAT Osteoclast-stimulating factor 1 OS=... | 53 | 0.005 | 42.4 | 38 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 108 | Q80U40 | 1072 | RIMB2_MOUSE RIMS-binding protein 2 OS=Mus mus... | 66 | 0.005 | 43.9 | 36 | 55 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 109 | Q6Y5D8 | 786 | RHG10_MOUSE Rho GTPase-activating protein 10 ... | 101 | 0.005 | 43.5 | 28 | 42 | GO:0005829; C:cytosol; IMP:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IPI:MGI.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IMP:MGI.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 110 | P54100 | 843 | VAV_RAT Proto-oncogene vav OS=Rattus norvegic... | 61 | 0.005 | 43.5 | 38 | 52 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0048468; P:cell development; TAS:RGD.::GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; IEP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 111 | Q5XHY7 | 523 | STAM2_RAT Signal transducing adapter molecule... | 64 | 0.006 | 43.5 | 39 | 56 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 112 | Q62422 | 215 | OSTF1_MOUSE Osteoclast-stimulating factor 1 O... | 53 | 0.006 | 42.4 | 38 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IDA:MGI. | | | | | | | | | | | 113 | Q4R729 | 692 | SH321_MACFA SH3 domain-containing protein 21 ... | 49 | 0.006 | 43.5 | 31 | 63 | | | | | | | | | | | | | | | | | | | | | | 114 | O00160 | 1098 | MYO1F_HUMAN Unconventional myosin-If OS=Homo ... | 71 | 0.006 | 43.5 | 37 | 54 | GO:0016461; C:unconventional myosin complex; NAS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; NAS:UniProtKB.::GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; NAS:UniProtKB.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 115 | O01498 | 457 | STAM1_CAEEL Signal transducing adapter molecu... | 78 | 0.006 | 43.1 | 32 | 54 | GO:0044441; C:cilium part; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:WormBase.::GO:0033565; C:ESCRT-0 complex; IPI:WormBase. | | | | | | | | | | GO:0008022; F:protein C-terminus binding; IPI:WormBase.::GO:0043130; F:ubiquitin binding; IDA:WormBase. | | | | | | | | | | GO:0008333; P:endosome to lysosome transport; IMP:WormBase.::GO:0048013; P:ephrin receptor signaling pathway; IGI:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB. | 116 | Q62417 | 1290 | SRBS1_MOUSE Sorbin and SH3 domain-containing ... | 67 | 3.3 | 34.7 | 28 | 51 | GO:0005913; C:cell-cell adherens junction; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0001725; C:stress fiber; IDA:UniProtKB. | | | | | | | | | | GO:0005158; F:insulin receptor binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IDA:MGI.::GO:0005070; F:SH3/SH2 adaptor activity; IPI:BHF-UCL. | | | | | | | | | | GO:0048041; P:focal adhesion assembly; IDA:UniProtKB.::GO:0015758; P:glucose transport; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.::GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:BHF-UCL.::GO:0043149; P:stress fiber assembly; IDA:UniProtKB. | 117 | Q9ULH1 | 1129 | ASAP1_HUMAN Arf-GAP with SH3 domain, ANK repe... | 89 | 0.006 | 43.5 | 34 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 118 | Q9DC07 | 270 | LNEBL_MOUSE LIM zinc-binding domain-containin... | 52 | 0.47 | 36.6 | 35 | 52 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 119 | Q75JD4 | 533 | Y1676_DICDI SH3 and FCH domain-containing pro... | 256 | 0.18 | 38.5 | 21 | 41 | | | | | | | | | | | | | | | | | | | | | | 120 | Q5TCX8 | 1036 | M3KL4_HUMAN Mitogen-activated protein kinase ... | 52 | 0.007 | 43.5 | 37 | 58 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 121 | P70248 | 1099 | MYO1F_MOUSE Unconventional myosin-If OS=Mus m... | 75 | 1.7 | 35.4 | 27 | 47 | GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | |