Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR114W
Length:
633
Number of sequences:
5887
Description:
YHR114W BZZ1 SGDID:S000001156, Chr VIII from 338083-339984, Genome Release 64-1-1, Verified ORF, "SH3 domain protein implicated in the regulation of actin polymerization, able to recruit actin polymerization machinery through its SH3 domains, colocalizes with cortical actin patches and Las17p, interacts with type I myosins"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361A6NI72    391   NCF1B_HUMAN Putative neutrophil cytosol facto...532.3     34.7     28     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
362P42684    1182   ABL2_HUMAN Abelson tyrosine-protein kinase 2 ...772.3     35     29     51GO:0015629; C:actin cytoskeleton; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0051015; F:actin filament binding; TAS:UniProtKB.::GO:0003785; F:actin monomer binding; TAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0051353; P:positive regulation of oxidoreductase activity; IDA:BHF-UCL.::GO:2000249; P:regulation of actin cytoskeleton reorganization; TAS:UniProtKB.::GO:0010506; P:regulation of autophagy; TAS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; TAS:UniProtKB.::GO:2000145; P:regulation of cell motility; TAS:UniProtKB.::GO:0030100; P:regulation of endocytosis; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.
363P14598    390   NCF1_HUMAN Neutrophil cytosol factor 1 OS=Hom...532.3     34.7     28     53GO:0005829; C:cytosol; TAS:ProtInc.::GO:0043020; C:NADPH oxidase complex; TAS:BHF-UCL.::GO:0032010; C:phagolysosome; TAS:Reactome.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0006612; P:protein targeting to membrane; IDA:UniProtKB.::GO:0042554; P:superoxide anion generation; TAS:BHF-UCL.
364Q4JIM5    1182   ABL2_MOUSE Abelson tyrosine-protein kinase 2 ...772.5     35     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030145; F:manganese ion binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
365Q6DII7    345   SKAP1_XENTR Src kinase-associated phosphoprot...392.5     34.7     38     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
366Q751J2    330   SHO1_ASHGO High osmolarity signaling protein ...562.5     34.7     39     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
367Q60780    421   GAS7_MOUSE Growth arrest-specific protein 7 O...1932.6     34.7     18     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
368E7FBF7    897   FCHO1_DANRE FCH domain only protein 1 OS=Dani...2172.6     35     20     38
369Q99963    347   SH3G3_HUMAN Endophilin-A3 OS=Homo sapiens (Hu...1002.6     34.7     26     40GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.
370Q8I1A6    366   SH3G3_DROWI Endophilin-A OS=Drosophila willis...512.9     34.3     35     53GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB.
GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB.
371Q4WHP5    584   HSE1_ASPFU Class E vacuolar protein-sorting m...1443.1     34.7     24     41GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
372P09769    529   FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo...513.1     34.7     29     59GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034988; F:Fc-gamma receptor I complex binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0001784; F:phosphotyrosine binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0050830; P:defense response to Gram-positive bacterium; ISS:UniProtKB.::GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; TAS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045088; P:regulation of innate immune response; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; ISS:UniProtKB.::GO:0009615; P:response to virus; TAS:ProtInc.
373P10686    1290   PLCG1_RAT 1-phosphatidylinositol 4,5-bisphosp...523.3     34.7     37     60GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0051219; F:phosphoprotein binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0006816; P:calcium ion transport; IMP:RGD.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0032959; P:inositol trisphosphate biosynthetic process; IMP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0032236; P:positive regulation of calcium ion transport via store-operated calcium channel activity; IMP:RGD.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:RGD.::GO:0009306; P:protein secretion; IMP:RGD.::GO:0009629; P:response to gravity; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0043278; P:response to morphine; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.
374Q62077    1302   PLCG1_MOUSE 1-phosphatidylinositol 4,5-bispho...523.3     34.7     37     60GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0035254; F:glutamate receptor binding; IPI:MGI.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI.
375Q9XYM0    271   CRK_DROME Adapter molecule Crk OS=Drosophila ...1553.6     33.9     23     43
GO:0005070; F:SH3/SH2 adaptor activity; IDA:FlyBase.
GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0007520; P:myoblast fusion; TAS:FlyBase.::GO:0046330; P:positive regulation of JNK cascade; IDA:FlyBase.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB.
376Q6AYE2    365   SHLB1_RAT Endophilin-B1 OS=Rattus norvegicus ...1093.8     33.9     28     39GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
377Q4ACU6    1805   SHAN3_MOUSE SH3 and multiple ankyrin repeat d...553.8     34.7     33     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; IC:BHF-UCL.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.::GO:0014069; C:postsynaptic density; ISS:BHF-UCL.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0030160; F:GKAP/Homer scaffold activity; ISS:BHF-UCL.::GO:0035255; F:ionotropic glutamate receptor binding; IPI:BHF-UCL.::GO:0008022; F:protein C-terminus binding; IPI:BHF-UCL.::GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.
GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering; IMP:BHF-UCL.::GO:0048854; P:brain morphogenesis; IMP:BHF-UCL.::GO:0060997; P:dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0001838; P:embryonic epithelial tube formation; IGI:MGI.::GO:0097117; P:guanylate kinase-associated protein clustering; IMP:BHF-UCL.::GO:0007612; P:learning; IMP:BHF-UCL.::GO:0035641; P:locomotory exploration behavior; IMP:BHF-UCL.::GO:0007613; P:memory; IMP:BHF-UCL.::GO:0097114; P:N-methyl-D-aspartate receptor clustering; IMP:BHF-UCL.::GO:0032232; P:negative regulation of actin filament bundle assembly; IDA:MGI.::GO:0045794; P:negative regulation of cell volume; IMP:BHF-UCL.::GO:0050885; P:neuromuscular process controlling balance; IMP:BHF-UCL.::GO:2000969; P:positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IMP:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IMP:BHF-UCL.::GO:0048170; P:positive regulation of long-term neuronal synaptic plasticity; IMP:BHF-UCL.::GO:0051835; P:positive regulation of synapse structural plasticity; IMP:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IMP:BHF-UCL.::GO:0097107; P:postsynaptic density assembly; IMP:BHF-UCL.::GO:2000822; P:regulation of behavioral fear response; IMP:BHF-UCL.::GO:2000821; P:regulation of grooming behavior; IMP:BHF-UCL.::GO:1900271; P:regulation of long-term synaptic potentiation; IMP:BHF-UCL.::GO:0035176; P:social behavior; IMP:BHF-UCL.::GO:0021773; P:striatal medium spiny neuron differentiation; IMP:BHF-UCL.::GO:0071625; P:vocalization behavior; IMP:BHF-UCL.
378Q5RDK0    564   ARHG9_PONAB Rho guanine nucleotide exchange f...553.9     34.3     25     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
379A1DBH2    1250   MYO1_NEOFI Myosin-1 OS=181) (Aspergillus fisc...513.9     34.3     31     57GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
380Q9JLU4    1815   SHAN3_RAT SH3 and multiple ankyrin repeat dom...553.9     34.3     33     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0060170; C:cilium membrane; IDA:BHF-UCL.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0030160; F:GKAP/Homer scaffold activity; IDA:BHF-UCL.::GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.::GO:0008022; F:protein C-terminus binding; IPI:BHF-UCL.::GO:0043621; F:protein self-association; IDA:RGD.::GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.::GO:0017124; F:SH3 domain binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IDA:RGD.
GO:0048854; P:brain morphogenesis; ISS:BHF-UCL.::GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0035641; P:locomotory exploration behavior; ISS:BHF-UCL.::GO:0045794; P:negative regulation of cell volume; ISS:BHF-UCL.::GO:2000969; P:positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0048170; P:positive regulation of long-term neuronal synaptic plasticity; ISS:BHF-UCL.::GO:0051835; P:positive regulation of synapse structural plasticity; ISS:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.::GO:0097107; P:postsynaptic density assembly; ISS:BHF-UCL.::GO:0051259; P:protein oligomerization; IDA:RGD.::GO:2000822; P:regulation of behavioral fear response; ISS:BHF-UCL.::GO:0035176; P:social behavior; ISS:BHF-UCL.::GO:0021773; P:striatal medium spiny neuron differentiation; ISS:BHF-UCL.::GO:0071625; P:vocalization behavior; ISS:BHF-UCL.
381Q9BYB0    1741   SHAN3_HUMAN SH3 and multiple ankyrin repeat d...553.9     34.3     33     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0060170; C:cilium membrane; ISS:BHF-UCL.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; ISS:BHF-UCL.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0030160; F:GKAP/Homer scaffold activity; ISS:BHF-UCL.::GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.::GO:0008022; F:protein C-terminus binding; ISS:BHF-UCL.::GO:0097110; F:scaffold protein binding; ISS:BHF-UCL.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor clustering; ISS:BHF-UCL.::GO:0048854; P:brain morphogenesis; ISS:BHF-UCL.::GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0097117; P:guanylate kinase-associated protein clustering; ISS:BHF-UCL.::GO:0007612; P:learning; ISS:BHF-UCL.::GO:0035641; P:locomotory exploration behavior; ISS:BHF-UCL.::GO:0007613; P:memory; ISS:BHF-UCL.::GO:0097114; P:N-methyl-D-aspartate receptor clustering; ISS:BHF-UCL.::GO:0045794; P:negative regulation of cell volume; ISS:BHF-UCL.::GO:0050885; P:neuromuscular process controlling balance; ISS:BHF-UCL.::GO:2000969; P:positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0048170; P:positive regulation of long-term neuronal synaptic plasticity; ISS:BHF-UCL.::GO:0051835; P:positive regulation of synapse structural plasticity; ISS:BHF-UCL.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.::GO:0097107; P:postsynaptic density assembly; ISS:BHF-UCL.::GO:2000822; P:regulation of behavioral fear response; ISS:BHF-UCL.::GO:1900271; P:regulation of long-term synaptic potentiation; ISS:BHF-UCL.::GO:0035176; P:social behavior; ISS:BHF-UCL.::GO:0021773; P:striatal medium spiny neuron differentiation; ISS:BHF-UCL.::GO:0071625; P:vocalization behavior; ISS:BHF-UCL.
382Q62415    1087   ASPP1_MOUSE Apoptosis-stimulating of p53 prot...314.1     34.3     48     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.
383Q63787    724   P85A_RAT Phosphatidylinositol 3-kinase regula...734.8     33.9     33     49GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:RGD.::GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IDA:RGD.::GO:0051117; F:ATPase binding; IPI:RGD.::GO:0005516; F:calmodulin binding; IPI:RGD.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; IPI:RGD.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:RGD.::GO:0051219; F:phosphoprotein binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IDA:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0030971; F:receptor tyrosine kinase binding; IPI:RGD.::GO:0031625; F:ubiquitin protein ligase binding; IPI:RGD.
GO:0071398; P:cellular response to fatty acid; IEP:RGD.::GO:0006006; P:glucose metabolic process; IMP:RGD.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0045776; P:negative regulation of blood pressure; IMP:RGD.::GO:0022408; P:negative regulation of cell-cell adhesion; IMP:RGD.::GO:0010459; P:negative regulation of heart rate; IMP:RGD.::GO:0045861; P:negative regulation of proteolysis; IMP:RGD.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0045768; P:positive regulation of anti-apoptosis; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0045663; P:positive regulation of myoblast differentiation; IMP:RGD.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0051591; P:response to cAMP; IDA:RGD.::GO:0071548; P:response to dexamethasone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0009750; P:response to fructose stimulus; IEP:RGD.::GO:0070848; P:response to growth factor stimulus; IEP:RGD.::GO:0010040; P:response to iron(II) ion; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.::GO:0001878; P:response to yeast; IEP:RGD.
384P26450    724   P85A_MOUSE Phosphatidylinositol 3-kinase regu...734.9     33.9     33     49GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:MGI.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB.
GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0034644; P:cellular response to UV; IMP:MGI.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.::GO:0001953; P:negative regulation of cell-matrix adhesion; IGI:MGI.::GO:0045671; P:negative regulation of osteoclast differentiation; IGI:MGI.::GO:0051531; P:NFAT protein import into nucleus; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0030335; P:positive regulation of cell migration; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI.
385A8G434    300   HSLO_PROM2 33 kDa chaperonin OS=Prochlorococc...1645.1     33.5     26     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
386P14238    820   FES_FELCA Tyrosine-protein kinase Fes/Fps OS=...2505.2     33.9     22     44GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0015630; C:microtubule cytoskeleton; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034987; F:immunoglobulin receptor binding; ISS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0031116; P:positive regulation of microtubule polymerization; ISS:UniProtKB.::GO:0045639; P:positive regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB.
387Q8TEC5    729   SH3R2_HUMAN Putative E3 ubiquitin-protein lig...505.3     33.9     34     54
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; IDA:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
388P38479    617   ABP1_SACEX Actin-binding protein OS=Saccharom...795.6     33.9     38     49GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
389O77774    392   NCF1_BOVIN Neutrophil cytosol factor 1 OS=Bos...535.7     33.5     28     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0006612; P:protein targeting to membrane; ISS:UniProtKB.
390A0JNJ1    403   STAC_BOVIN SH3 and cysteine-rich domain-conta...615.7     33.5     28     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
391Q5R685    724   P85A_PONAB Phosphatidylinositol 3-kinase regu...735.8     33.9     33     49GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro.
GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
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