Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR114W
Length:
633
Number of sequences:
5887
Description:
YHR114W BZZ1 SGDID:S000001156, Chr VIII from 338083-339984, Genome Release 64-1-1, Verified ORF, "SH3 domain protein implicated in the regulation of actin polymerization, able to recruit actin polymerization machinery through its SH3 domains, colocalizes with cortical actin patches and Las17p, interacts with type I myosins"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301Q8BUR4    1865   DOCK1_MOUSE Dedicator of cytokinesis protein ...510.54     37.4     37     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IDA:MGI.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.
302O77506    263   LASP1_RABIT LIM and SH3 domain protein 1 OS=O...512     34.7     41     57GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.
303Q8I190    369   SH3G3_DROVI Endophilin-A OS=Drosophila virili...730.57     36.6     33     48GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB.
GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB.
304A7E3N2    527   NCF2_RAT Neutrophil cytosol factor 2 OS=Rattu...533.1     34.7     28     55GO:0005624; C:membrane fraction; IDA:RGD.
GO:0007568; P:aging; IEP:RGD.::GO:0032870; P:cellular response to hormone stimulus; IDA:RGD.::GO:0045777; P:positive regulation of blood pressure; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IDA:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0034616; P:response to laminar fluid shear stress; IEP:RGD.::GO:0033993; P:response to lipid; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IDA:RGD.::GO:0014070; P:response to organic cyclic compound; IDA:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD.
305Q04929    305   CRK_CHICK Adapter molecule crk OS=Gallus gall...1580.57     36.6     22     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB.
306Q8I1C0    369   SH3G3_DROPS Endophilin-A OS=Drosophila pseudo...730.57     36.6     33     48GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB.
GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB.
307A5D8S5    867   SH3R1_DANRE E3 ubiquitin-protein ligase SH3RF...600.62     37     32     52GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
308A2R5J1    1270   MYO1_ASPNC Myosin-1 OS=Aspergillus niger (str...520.62     37     35     56GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
309A1DFN5    603   HSE1_NEOFI Class E vacuolar protein-sorting m...1440.65     36.6     22     42GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
310Q5RAQ2    342   SH3Y1_PONAB SH3 domain-containing YSC84-like ...520.67     36.6     35     56
311Q9UKW4    847   VAV3_HUMAN Guanine nucleotide exchange factor...480.67     37     33     56GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0030890; P:positive regulation of B cell proliferation; IMP:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0006974; P:response to DNA damage stimulus; IMP:UniProtKB.::GO:0042493; P:response to drug; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
312Q8CIH5    1265   PLCG2_MOUSE 1-phosphatidylinositol 4,5-bispho...560.68     37     29     57GO:0005829; C:cytosol; IMP:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0004435; F:phosphatidylinositol phospholipase C activity; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0032237; P:activation of store-operated calcium channel activity; IMP:MGI.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0002316; P:follicular B cell differentiation; IMP:MGI.::GO:0032959; P:inositol trisphosphate biosynthetic process; IDA:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043069; P:negative regulation of programmed cell death; IMP:MGI.::GO:0006661; P:phosphatidylinositol biosynthetic process; ISS:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010468; P:regulation of gene expression; IMP:MGI.::GO:0051209; P:release of sequestered calcium ion into cytosol; IMP:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; IDA:MGI.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI.
313Q96HL8    342   SH3Y1_HUMAN SH3 domain-containing YSC84-like ...520.69     36.2     35     56
314P24135    1265   PLCG2_RAT 1-phosphatidylinositol 4,5-bisphosp...560.71     37     29     57GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006661; P:phosphatidylinositol biosynthetic process; ISS:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0033198; P:response to ATP; IDA:RGD.::GO:0032026; P:response to magnesium ion; IDA:RGD.
315P17671    1199   E75BC_DROME Ecdysone-induced protein 75B, iso...760.72     37     33     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0020037; F:heme binding; IDA:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.::GO:0004887; F:thyroid hormone receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0019730; P:antimicrobial humoral response; IMP:FlyBase.::GO:0018990; P:ecdysis, chitin-based cuticle; IMP:FlyBase.::GO:0035072; P:ecdysone-mediated induction of salivary gland cell autophagic cell death; NAS:FlyBase.::GO:0048477; P:oogenesis; NAS:FlyBase.::GO:0007553; P:regulation of ecdysteroid metabolic process; IMP:FlyBase.
316Q12163    236   NBP2_YEAST NAP1-binding protein 2 OS=Saccharo...510.73     35.8     31     57GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; TAS:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006972; P:hyperosmotic response; IPI:SGD.::GO:0006469; P:negative regulation of protein kinase activity; IDA:SGD.::GO:0009408; P:response to heat; IMP:SGD.
317O42854    1611   YFHH_SCHPO SH3 domain-containing protein C23A...630.73     37     33     54GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0017024; F:myosin I binding; ISS:PomBase.
GO:0030036; P:actin cytoskeleton organization; ISS:PomBase.
318Q5BBL4    581   HSE1_EMENI Class E vacuolar protein-sorting m...1580.73     36.6     23     41GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
319Q6FN49    450   HSE1_CANGA Class E vacuolar protein-sorting m...540.76     36.6     33     48GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
320Q54GD0    920   MGP1_DICDI Mental retardation GTPase activati...2560.77     36.6     21     43GO:0000331; C:contractile vacuole; IDA:dictyBase.::GO:0005829; C:cytosol; IDA:dictyBase.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0033298; P:contractile vacuole organization; IMP:dictyBase.::GO:0006887; P:exocytosis; IGI:dictyBase.::GO:0051490; P:negative regulation of filopodium assembly; IMP:dictyBase.::GO:0042331; P:phototaxis; IGI:dictyBase.::GO:0051270; P:regulation of cellular component movement; IMP:dictyBase.::GO:0007165; P:signal transduction; IEA:InterPro.
321Q6EV77    575   FUT8_PANTR Alpha-(1,6)-fucosyltransferase OS=...510.81     36.6     39     57GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008424; F:glycoprotein 6-alpha-L-fucosyltransferase activity; IEA:EC.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0033578; P:protein glycosylation in Golgi; IEA:InterPro.
322Q9BYC5    575   FUT8_HUMAN Alpha-(1,6)-fucosyltransferase OS=...510.81     36.6     39     57GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008424; F:glycoprotein 6-alpha-L-fucosyltransferase activity; TAS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0001701; P:in utero embryonic development; NAS:UniProtKB.::GO:0042355; P:L-fucose catabolic process; NAS:UniProtKB.::GO:0006491; P:N-glycan processing; TAS:UniProtKB.::GO:0009312; P:oligosaccharide biosynthetic process; TAS:ProtInc.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0033578; P:protein glycosylation in Golgi; IEA:InterPro.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
323Q5NVB3    574   FUT8_PONAB Alpha-(1,6)-fucosyltransferase OS=...510.83     36.6     39     57GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008424; F:glycoprotein 6-alpha-L-fucosyltransferase activity; IEA:EC.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0033578; P:protein glycosylation in Golgi; IEA:InterPro.
324Q60992    868   VAV2_MOUSE Guanine nucleotide exchange factor...908.2     33.1     29     41GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005154; F:epidermal growth factor receptor binding; IPI:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IGI:MGI.::GO:0030032; P:lamellipodium assembly; IGI:MGI.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IMP:MGI.
325O08838    683   AMPH_RAT Amphiphysin OS=Rattus norvegicus (Ra...660.84     36.6     30     52GO:0043679; C:axon terminus; IDA:RGD.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0046982; F:protein heterodimerization activity; IPI:RGD.
GO:0045807; P:positive regulation of endocytosis; IMP:RGD.::GO:0043547; P:positive regulation of GTPase activity; IDA:RGD.
326P32793    468   YSC84_YEAST Protein YSC84 OS=Saccharomyces ce...540.9     36.2     28     56GO:0030479; C:actin cortical patch; IDA:SGD.
GO:0051015; F:actin filament binding; IDA:SGD.
GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0051017; P:actin filament bundle assembly; IDA:SGD.::GO:0006897; P:endocytosis; IGI:SGD.
327Q8AXU9    353   SH3G3_CHICK Endophilin-A3 OS=Gallus gallus (C...510.91     36.2     33     53GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
328Q54QF4    909   MGP4_DICDI Mental retardation GTPase activati...2190.92     36.6     18     40GO:0000331; C:contractile vacuole; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
329P50478    682   AMPH_CHICK Amphiphysin OS=Gallus gallus (Chic...660.93     36.2     29     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:AgBase.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:AgBase.
330Q0CEX5    1246   MYO1_ASPTN Myosin-1 OS=Aspergillus terreus (s...520.94     36.6     33     56GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
331E7A253    343   SHO1_SPORE High osmolarity signaling protein ...583.7     33.9     34     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
records
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