Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR114W
Length:
633
Number of sequences:
5887
Description:
YHR114W BZZ1 SGDID:S000001156, Chr VIII from 338083-339984, Genome Release 64-1-1, Verified ORF, "SH3 domain protein implicated in the regulation of actin polymerization, able to recruit actin polymerization machinery through its SH3 domains, colocalizes with cortical actin patches and Las17p, interacts with type I myosins"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q66II3    229   GRB2_XENTR Growth factor receptor-bound prote...540.2     37.7     35     54GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005154; F:epidermal growth factor receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.
GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
212Q99JB8    424   PACN3_MOUSE Protein kinase C and casein kinas...573.4     34.3     25     49GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008092; F:cytoskeletal protein binding; IDA:MGI.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; IDA:MGI.
213Q5ZMW5    760   RHG26_CHICK Rho GTPase-activating protein 26 ...546.3     33.5     31     46GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
214Q9Y566    2161   SHAN1_HUMAN SH3 and multiple ankyrin repeat d...550.098     39.7     36     58GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; ISS:BHF-UCL.::GO:0005886; C:plasma membrane; ISS:BHF-UCL.::GO:0014069; C:postsynaptic density; ISS:BHF-UCL.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:BHF-UCL.
GO:0071532; F:ankyrin repeat binding; ISS:BHF-UCL.::GO:0030160; F:GKAP/Homer scaffold activity; ISS:BHF-UCL.::GO:0042802; F:identical protein binding; ISS:BHF-UCL.::GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.::GO:0097110; F:scaffold protein binding; ISS:BHF-UCL.::GO:0017124; F:SH3 domain binding; ISS:BHF-UCL.
GO:0008306; P:associative learning; ISS:BHF-UCL.::GO:0007016; P:cytoskeletal anchoring at plasma membrane; NAS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0007616; P:long-term memory; ISS:BHF-UCL.::GO:0050885; P:neuromuscular process controlling balance; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0006461; P:protein complex assembly; ISS:BHF-UCL.::GO:0035418; P:protein localization to synapse; ISS:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.
215O89100    322   GRAP2_MOUSE GRB2-related adaptor protein 2 OS...540.099     38.9     35     54GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:MGI.
216O15034    1052   RIMB2_HUMAN RIMS-binding protein 2 OS=Homo sa...610.099     39.7     36     56GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
217P42686    505   SRK1_SPOLA Tyrosine-protein kinase isoform SR...490.1     39.3     31     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
218A6H7G2    423   DBNL_BOVIN Drebrin-like protein OS=Bos taurus...500.11     39.3     40     56GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
219Q9CX99    217   GRAP_MOUSE GRB2-related adapter protein OS=Mu...533.2     33.9     28     47
220Q95UN8    1161   M3KSL_DROME Mitogen-activated protein kinase ...740.11     39.3     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0007257; P:activation of JUN kinase activity; IMP:UniProtKB.::GO:0071361; P:cellular response to ethanol; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0007394; P:dorsal closure, elongation of leading edge cells; IMP:FlyBase.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0048804; P:imaginal disc-derived female genitalia morphogenesis; IMP:FlyBase.::GO:0048803; P:imaginal disc-derived male genitalia morphogenesis; IMP:FlyBase.::GO:0046330; P:positive regulation of JNK cascade; IMP:FlyBase.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
221Q8BKX1    535   BAIP2_MOUSE Brain-specific angiogenesis inhib...560.11     39.3     36     63GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0070064; F:proline-rich region binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0051017; P:actin filament bundle assembly; IGI:MGI.::GO:0016358; P:dendrite development; IMP:MGI.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0048167; P:regulation of synaptic plasticity; IMP:MGI.::GO:0009617; P:response to bacterium; ISS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; TAS:MGI.
222O77775    527   NCF2_BOVIN Neutrophil cytosol factor 2 OS=Bos...480.11     39.3     35     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
223Q6GMN2    535   BAIP2_RAT Brain-specific angiogenesis inhibit...560.12     39.3     36     63GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0070064; F:proline-rich region binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0009617; P:response to bacterium; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
224Q8TE67    593   ES8L3_HUMAN Epidermal growth factor receptor ...1600.12     39.3     22     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
225O74352    466   HOB1_SCHPO Protein hob1 OS=Schizosaccharomyce...510.12     38.9     37     57GO:0051285; C:cell cortex of cell tip; TAS:PomBase.::GO:0031097; C:medial cortex; TAS:PomBase.
GO:0051020; F:GTPase binding; NAS:PomBase.
GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0006348; P:chromatin silencing at telomere; IMP:PomBase.::GO:0007163; P:establishment or maintenance of cell polarity; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0006974; P:response to DNA damage stimulus; IGI:PomBase.::GO:0000723; P:telomere maintenance; IMP:PomBase.
226Q07883    217   GRB2_CHICK Growth factor receptor-bound prote...510.15     38.1     31     55GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
227Q5U464    904   ASAP3_MOUSE Arf-GAP with SH3 domain, ANK repe...1780.12     39.3     25     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
228P42690    506   SRK4_SPOLA Tyrosine-protein kinase isoform SR...490.12     38.9     31     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
229O89032    1124   SPD2A_MOUSE SH3 and PX domain-containing prot...1530.13     39.3     27     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.
230Q6CHN0    1136   SLA1_YARLI Actin cytoskeleton-regulatory comp...546.1     33.9     31     57GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
231Q4VAA7    574   SNX33_MOUSE Sorting nexin-33 OS=Mus musculus ...560.14     38.9     30     59
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
232Q08DN7    844   VAV_BOVIN Proto-oncogene vav OS=Bos taurus (B...510.14     38.9     35     55GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
233Q60437    521   BAIP2_CRIGR Brain-specific angiogenesis inhib...560.14     38.9     36     63GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0070064; F:proline-rich region binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0009617; P:response to bacterium; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
234P57075    661   UBS3A_HUMAN Ubiquitin-associated and SH3 doma...570.15     38.9     35     58GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
235O95153    1857   RIMB1_HUMAN Peripheral-type benzodiazepine re...870.15     38.9     33     48GO:0005739; C:mitochondrion; IDA:UniProtKB.
GO:0030156; F:benzodiazepine receptor binding; IPI:UniProtKB.
236Q54CL3    570   PEX13_DICDI Probable peroxisomal membrane pro...520.17     38.5     33     56GO:0005779; C:integral to peroxisomal membrane; ISS:dictyBase.
GO:0016560; P:protein import into peroxisome matrix, docking; ISS:dictyBase.
237Q9UHR4    511   BI2L1_HUMAN Brain-specific angiogenesis inhib...400.17     38.5     43     63GO:0030054; C:cell junction; IDA:HPA.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0070064; F:proline-rich region binding; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:UniProtKB.::GO:0009617; P:response to bacterium; IDA:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
238P34258    493   YKA7_CAEEL Uncharacterized protein B0303.7 OS...1356.3     33.5     20     43
239Q5EAD0    521   BAIP2_BOVIN Brain-specific angiogenesis inhib...560.18     38.5     36     63GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0070064; F:proline-rich region binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0009617; P:response to bacterium; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
240Q5U4T3    771   RHG26_XENLA Rho GTPase-activating protein 26 ...520.18     38.5     33     50GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
241Q3KR97    516   BI2L1_RAT Brain-specific angiogenesis inhibit...400.19     38.5     40     65GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0070064; F:proline-rich region binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0030838; P:positive regulation of actin filament polymerization; ISS:UniProtKB.::GO:0009617; P:response to bacterium; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
records
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