Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR105W
Length:
214
Number of sequences:
5887
Description:
YHR105W YPT35 SGDID:S000001147, Chr VIII from 324766-325410, Genome Release 64-1-1, Verified ORF, "Endosomal protein of unknown function that contains a phox (PX) homology domain and binds to both phosphatidylinositol-3-phosphate (PtdIns(3)P) and proteins involved in ER-Golgi or vesicular transport"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38815    214   YPT35_YEAST PX domain-containing protein YPT3...2146e-159     445     100     100GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007154; P:cell communication; IEA:InterPro.
2A6ZT13    214   YPT35_YEAS7 PX domain-containing protein YPT3...2142e-158     444     99     100GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
3Q6FR40    173   YPT35_CANGA PX domain-containing protein YPT3...2121e-52     173     44     62GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
4A7TKX9    174   YPT35_VANPO PX domain-containing protein YPT3...1489e-21     90.1     32     55GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
5Q75CM7    171   YPT35_ASHGO PX domain-containing protein YPT3...2080.00000000003     62.8     28     40GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
6Q6BIS2    157   YPT35_DEBHA PX domain-containing protein YPT3...1290.00000000004     62.4     27     50GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
7Q5AG56    167   YPT35_CANAL PX domain-containing protein YPT3...1150.0000005     51.2     25     53GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
8A5DHC9    145   YPT35_PICGU PX domain-containing protein YPT3...1250.000006     47.8     25     45GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
9Q8BX57    582   PXK_MOUSE PX domain-containing protein kinase...920.018     39.3     33     53GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:InterPro.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0004672; F:protein kinase activity; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0032780; P:negative regulation of ATPase activity; IDA:UniProtKB.::GO:0043271; P:negative regulation of ion transport; IDA:UniProtKB.::GO:0050804; P:regulation of synaptic transmission; IEP:UniProtKB.
10Q08DD7    270   SNX11_BOVIN Sorting nexin-11 OS=Bos taurus (B...1100.021     38.5     27     48GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
11Q6PHS6    957   SNX13_MOUSE Sorting nexin-13 OS=Mus musculus ...1270.025     38.9     32     51GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
12Q9Y5W9    270   SNX11_HUMAN Sorting nexin-11 OS=Homo sapiens ...1100.032     38.1     26     48GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
13Q5R6Q7    344   SNX16_PONAB Sorting nexin-16 OS=Pongo abelii ...1410.033     38.1     27     43GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0031313; C:extrinsic to endosome membrane; ISS:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.::GO:0006622; P:protein targeting to lysosome; ISS:UniProtKB.
14P57768    344   SNX16_HUMAN Sorting nexin-16 OS=Homo sapiens ...1410.048     37.7     27     43GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0031313; C:extrinsic to endosome membrane; IDA:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.::GO:0008333; P:endosome to lysosome transport; IMP:UniProtKB.::GO:0006622; P:protein targeting to lysosome; IMP:UniProtKB.
15Q91WL6    271   SNX11_MOUSE Sorting nexin-11 OS=Mus musculus ...1100.05     37.7     26     47GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
16P40959    511   MVP1_YEAST Sorting nexin MVP1 OS=Saccharomyce...1080.052     37.7     31     49GO:0005737; C:cytoplasm; IDA:SGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0006623; P:protein targeting to vacuole; IMP:SGD.
17Q4FZZ1    580   PXK_RAT PX domain-containing protein kinase-l...930.055     37.7     31     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:InterPro.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0050804; P:regulation of synaptic transmission; ISS:UniProtKB.
18Q4PHC3    683   MVP1_USTMA Sorting nexin MVP1 OS=Ustilago may...1210.057     37.7     30     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
19Q8C080    344   SNX16_MOUSE Sorting nexin-16 OS=Mus musculus ...1790.081     37     25     41GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0031313; C:extrinsic to endosome membrane; ISS:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.::GO:0006622; P:protein targeting to lysosome; ISS:UniProtKB.
20Q75CC3    524   MVP1_ASHGO Sorting nexin MVP1 OS=Y-1056) (Yea...870.1     37     33     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
21P57769    344   SNX16_RAT Sorting nexin-16 OS=Rattus norvegic...1070.11     36.6     28     46GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0031313; C:extrinsic to endosome membrane; ISS:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0045022; P:early endosome to late endosome transport; IDA:RGD.::GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.::GO:0006622; P:protein targeting to lysosome; ISS:UniProtKB.
22Q6FNH2    509   MVP1_CANGA Sorting nexin MVP1 OS=NRRL Y-65) (...870.14     36.6     34     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
23Q2KHV6    459   SNX8_BOVIN Sorting nexin-8 OS=Bos taurus (Bov...1180.31     35.4     26     45GO:0031901; C:early endosome membrane; ISS:UniProtKB.
GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0034498; P:early endosome to Golgi transport; ISS:UniProtKB.::GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
24Q96RF0    628   SNX18_HUMAN Sorting nexin-18 OS=Homo sapiens ...920.34     35.4     25     46GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:UniProtKB.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0006897; P:endocytosis; IDA:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
25Q7Z7A4    578   PXK_HUMAN PX domain-containing protein kinase...970.37     35.4     31     51GO:0005813; C:centrosome; IDA:HPA.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.::GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0006954; P:inflammatory response; IMP:UniProtKB.::GO:0032780; P:negative regulation of ATPase activity; ISS:UniProtKB.::GO:0043271; P:negative regulation of ion transport; ISS:UniProtKB.::GO:0050804; P:regulation of synaptic transmission; ISS:UniProtKB.
26Q3MPQ4    745   MVP1_CANAL Sorting nexin MVP1 OS=Candida albi...720.46     35     40     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
27Q91ZR2    614   SNX18_MOUSE Sorting nexin-18 OS=Mus musculus ...920.64     34.7     25     46GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
28Q9Y5X2    465   SNX8_HUMAN Sorting nexin-8 OS=Homo sapiens (H...771     33.9     26     52GO:0031901; C:early endosome membrane; IDA:UniProtKB.
GO:0035091; F:phosphatidylinositol binding; IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0034498; P:early endosome to Golgi transport; IMP:UniProtKB.::GO:0006886; P:intracellular protein transport; IMP:UniProtKB.
29Q6CUC4    512   MVP1_KLULA Sorting nexin MVP1 OS=1267 / NRRL ...871     33.9     31     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
30Q6CHY6    605   MVP1_YARLI Sorting nexin MVP1 OS=lipolytica)....811.1     33.9     32     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
31O70492    162   SNX3_MOUSE Sorting nexin-3 OS=Mus musculus (M...1181.4     32.7     25     45GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0010008; C:endosome membrane; ISS:UniProtKB.
GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
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