rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | O80944 | 311 | AKRC8_ARATH Aldo-keto reductase family 4 memb... | 284 | 2e-58 | 196 | 40 | 56 | GO:0005829; C:cytosol; IDA:TAIR. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; IDA:UniProtKB.::GO:0070401; F:NADP+ binding; IDA:UniProtKB.::GO:0016229; F:steroid dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009651; P:response to salt stress; IEP:UniProtKB.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW.::GO:0009414; P:response to water deprivation; IEP:UniProtKB. | 62 | P17516 | 323 | AK1C4_HUMAN Aldo-keto reductase family 1 memb... | 314 | 2e-58 | 197 | 38 | 57 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:ProtInc.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0015125; F:bile acid transmembrane transporter activity; TAS:ProtInc.::GO:0047743; F:chlordecone reductase activity; IEA:EC.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0008209; P:androgen metabolic process; TAS:ProtInc.::GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB. | 63 | Q568L5 | 324 | A1A1B_DANRE Alcohol dehydrogenase [NADP(+)] B... | 327 | 2e-58 | 197 | 36 | 56 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 64 | Q5R7C9 | 323 | AK1C3_PONAB Aldo-keto reductase family 1 memb... | 313 | 4e-58 | 196 | 37 | 57 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0047020; F:15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; ISS:UniProtKB.::GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; ISS:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0045703; F:ketoreductase activity; ISS:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; ISS:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; ISS:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; ISS:UniProtKB.::GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0004958; F:prostaglandin F receptor activity; ISS:UniProtKB.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.::GO:0001758; F:retinal dehydrogenase activity; ISS:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; ISS:UniProtKB.::GO:0071276; P:cellular response to cadmium ion; ISS:UniProtKB.::GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.::GO:0071384; P:cellular response to corticosteroid stimulus; ISS:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; ISS:UniProtKB.::GO:0071379; P:cellular response to prostaglandin stimulus; ISS:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; ISS:UniProtKB.::GO:0016488; P:farnesol catabolic process; ISS:UniProtKB.::GO:1900053; P:negative regulation of retinoic acid biosynthetic process; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; ISS:UniProtKB.::GO:0042448; P:progesterone metabolic process; ISS:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; ISS:UniProtKB.::GO:0048385; P:regulation of retinoic acid receptor signaling pathway; ISS:UniProtKB.::GO:2000224; P:regulation of testosterone biosynthetic process; ISS:UniProtKB.::GO:0042574; P:retinal metabolic process; ISS:UniProtKB.::GO:0061370; P:testosterone biosynthetic process; ISS:UniProtKB. | 65 | P28475 | 310 | S6PD_MALDO NADP-dependent D-sorbitol-6-phosph... | 317 | 6e-58 | 195 | 36 | 58 | | | | | | | | | | | GO:0047641; F:aldose-6-phosphate reductase (NADPH) activity; IEA:EC. | | | | | | | | | | | 66 | Q5ZK84 | 327 | AK1A1_CHICK Alcohol dehydrogenase [NADP(+)] O... | 320 | 7e-58 | 196 | 39 | 57 | | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | | 67 | Q5U1Y4 | 301 | AKCL2_RAT 1,5-anhydro-D-fructose reductase OS... | 303 | 2e-57 | 194 | 39 | 59 | | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 68 | P42330 | 323 | AK1C3_HUMAN Aldo-keto reductase family 1 memb... | 313 | 5e-57 | 193 | 37 | 57 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0047020; F:15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IDA:UniProtKB.::GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; IDA:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0045703; F:ketoreductase activity; IDA:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:EC. | | | | | | | | | | GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0071276; P:cellular response to cadmium ion; IDA:UniProtKB.::GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.::GO:0071384; P:cellular response to corticosteroid stimulus; IDA:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0071379; P:cellular response to prostaglandin stimulus; IDA:UniProtKB.::GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.::GO:0009267; P:cellular response to starvation; IEP:UniProtKB.::GO:0016488; P:farnesol catabolic process; IDA:UniProtKB.::GO:0030216; P:keratinocyte differentiation; IEP:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0044259; P:multicellular organismal macromolecule metabolic process; IEP:UniProtKB.::GO:1900053; P:negative regulation of retinoic acid biosynthetic process; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IDA:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; IDA:UniProtKB.::GO:0048385; P:regulation of retinoic acid receptor signaling pathway; IDA:UniProtKB.::GO:2000224; P:regulation of testosterone biosynthetic process; IMP:UniProtKB.::GO:0070293; P:renal absorption; NAS:UniProtKB.::GO:0007584; P:response to nutrient; IEP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0061370; P:testosterone biosynthetic process; IMP:UniProtKB. | 69 | Q96JD6 | 320 | AKCL2_HUMAN 1,5-anhydro-D-fructose reductase ... | 313 | 8e-57 | 192 | 37 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 70 | Q9DCT1 | 301 | AKCL2_MOUSE 1,5-anhydro-D-fructose reductase ... | 302 | 9e-57 | 192 | 39 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 71 | Q1XAA8 | 322 | AK1CN_HORSE Aldo-keto reductase family 1 memb... | 313 | 3e-56 | 191 | 38 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 72 | P21300 | 316 | ALD1_MOUSE Aldose reductase-related protein 1... | 320 | 4e-56 | 191 | 41 | 55 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | GO:0044255; P:cellular lipid metabolic process; TAS:MGI. | 73 | Q4R802 | 320 | AKCL2_MACFA 1,5-anhydro-D-fructose reductase ... | 313 | 6e-56 | 190 | 38 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC. | | | | | | | | | | | 74 | Q84TF0 | 314 | AKRCA_ARATH Aldo-keto reductase family 4 memb... | 283 | 1e-55 | 189 | 36 | 54 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 75 | P27800 | 323 | ALDX_SPOSA Aldehyde reductase 1 OS=Sporobolom... | 321 | 1e-55 | 189 | 35 | 54 | GO:0005623; C:cell; IDA:UniProtKB. | | | | | | | | | | GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:UniProtKB. | | | | | | | | | | | 76 | Q91WR5 | 323 | AK1CL_MOUSE Aldo-keto reductase family 1 memb... | 313 | 2e-55 | 189 | 36 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0033764; F:steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IDA:MGI. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 77 | P23457 | 322 | DIDH_RAT 3-alpha-hydroxysteroid dehydrogenase... | 320 | 2e-55 | 189 | 36 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC. | | | | | | | | | | GO:0021766; P:hippocampus development; IEP:RGD.::GO:0008202; P:steroid metabolic process; TAS:RGD. | 78 | P45377 | 316 | ALD2_MOUSE Aldose reductase-related protein 2... | 314 | 3e-55 | 188 | 40 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 79 | O42888 | 325 | YBN4_SCHPO Uncharacterized oxidoreductase C8E... | 308 | 4e-55 | 188 | 37 | 54 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0004033; F:aldo-keto reductase (NADP) activity; ISS:PomBase. | | | | | | | | | | GO:0019568; P:arabinose catabolic process; ISS:PomBase.::GO:0042843; P:D-xylose catabolic process; ISS:PomBase. | 80 | P80276 | 316 | ALDR_PIG Aldose reductase OS=Sus scrofa (Pig)... | 314 | 5e-55 | 188 | 40 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 81 | O08782 | 316 | ALD2_CRIGR Aldose reductase-related protein 2... | 314 | 6e-55 | 187 | 41 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 82 | Q5RJP0 | 316 | ALD1_RAT Aldose reductase-related protein 1 O... | 317 | 7e-55 | 187 | 40 | 56 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:RGD. | | | | | | | | | | | 83 | P15122 | 316 | ALDR_RABIT Aldose reductase OS=Oryctolagus cu... | 314 | 1e-54 | 187 | 40 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 84 | P16116 | 315 | ALDR_BOVIN Aldose reductase OS=Bos taurus (Bo... | 310 | 1e-54 | 187 | 40 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | | 85 | P17264 | 324 | CRO_LITCT Rho crystallin OS=Lithobates catesb... | 316 | 1e-54 | 187 | 35 | 57 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW. | | | | | | | | | | | 86 | C9JRZ8 | 344 | AK1BF_HUMAN Aldo-keto reductase family 1 memb... | 294 | 2e-54 | 187 | 39 | 56 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 87 | P51652 | 323 | AKC1H_RAT Aldo-keto reductase family 1 member... | 313 | 5e-54 | 185 | 34 | 58 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0050810; P:regulation of steroid biosynthetic process; IDA:RGD. | 88 | Q8K023 | 323 | AKC1H_MOUSE Aldo-keto reductase family 1 memb... | 313 | 9e-54 | 184 | 35 | 57 | | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IDA:MGI. | | | | | | | | | | GO:0007567; P:parturition; IMP:MGI.::GO:0006709; P:progesterone catabolic process; IDA:MGI. | 89 | P02532 | 324 | CRO_RANTE Rho crystallin OS=Rana temporaria (... | 316 | 1e-53 | 184 | 34 | 57 | | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW. | | | | | | | | | | | 90 | P26690 | 315 | 6DCS_SOYBN NAD(P)H-dependent 6'-deoxychalcone... | 308 | 6e-53 | 182 | 37 | 57 | | | | | | | | | | | GO:0033808; F:6'-deoxychalcone synthase activity; IEA:EC.::GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW. | 91 | P23901 | 320 | ALDR_HORVU Aldose reductase OS=Hordeum vulgar... | 283 | 1e-51 | 179 | 37 | 54 | | | | | | | | | | | GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC. | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. |