Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR104W
Length:
327
Number of sequences:
5887
Description:
YHR104W GRE3 SGDID:S000001146, Chr VIII from 323409-324392, Genome Release 64-1-1, Verified ORF, "Aldose reductase involved in methylglyoxal, d-xylose, arabinose, and galactose metabolism; stress induced (osmotic, ionic, oxidative, heat shock, starvation and heavy metals); regulated by the HOG pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P51857    326   AK1D1_HUMAN 3-oxo-5-beta-steroid 4-dehydrogen...3256e-69     224     40     58GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC.::GO:0005496; F:steroid binding; TAS:UniProtKB.
GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.::GO:0008207; P:C21-steroid hormone metabolic process; IDA:UniProtKB.::GO:0006707; P:cholesterol catabolic process; IDA:UniProtKB.::GO:0007586; P:digestion; IDA:UniProtKB.
32Q5R5D5    325   AK1A1_PONAB Alcohol dehydrogenase [NADP(+)] O...3228e-69     224     39     57
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
33Q6IMN8    297   ALRA_DICDI Aldose reductase A OS=Dictyosteliu...3164e-67     219     37     57GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:dictyBase.
GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0042593; P:glucose homeostasis; IMP:dictyBase.::GO:0031158; P:negative regulation of aggregate size involved in sorocarp development; IMP:dictyBase.::GO:0009617; P:response to bacterium; IEP:dictyBase.::GO:0006979; P:response to oxidative stress; IMP:dictyBase.
34Q9TV64    326   AK1D1_RABIT 3-oxo-5-beta-steroid 4-dehydrogen...3221e-66     218     40     56
GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC.
GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.
35P82125    301   AKCL2_PIG 1,5-anhydro-D-fructose reductase OS...3041e-64     212     40     58
GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:EC.
36Q6W8P9    323   AK1CO_HORSE Aldo-keto reductase family 1 memb...3111e-64     213     40     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.
37O60218    316   AK1BA_HUMAN Aldo-keto reductase family 1 memb...3172e-64     212     40     56GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:UniProtKB.::GO:0045550; F:geranylgeranyl reductase activity; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB.
GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006081; P:cellular aldehyde metabolic process; TAS:ProtInc.::GO:0007586; P:digestion; TAS:ProtInc.::GO:0016488; P:farnesol catabolic process; IDA:UniProtKB.::GO:0008202; P:steroid metabolic process; TAS:ProtInc.
38Q55FL3    321   ALRC_DICDI Aldose reductase C OS=Dictyosteliu...3212e-64     213     39     57
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:dictyBase.
GO:0005975; P:carbohydrate metabolic process; ISS:dictyBase.
39P31210    326   AK1D1_RAT 3-oxo-5-beta-steroid 4-dehydrogenas...3222e-64     212     39     58
GO:0047568; F:3-oxo-5-beta-steroid 4-dehydrogenase activity; IDA:MGI.::GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:EC.
GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.
40P05980    323   PGFS1_BOVIN Prostaglandin F synthase 1 OS=Bos...3182e-64     212     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.
GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW.
41Q10494    321   YDG7_SCHPO Uncharacterized oxidoreductase C26...3094e-64     212     39     59GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0047935; F:glucose 1-dehydrogenase (NADP+) activity; ISS:PomBase.
GO:0019568; P:arabinose catabolic process; ISS:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0042843; P:D-xylose catabolic process; ISS:PomBase.
42Q54NZ7    311   ALRB_DICDI Aldose reductase B OS=Dictyosteliu...3154e-64     211     39     56
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; ISS:dictyBase.
43Q6AZW2    324   A1A1A_DANRE Alcohol dehydrogenase [NADP(+)] A...3388e-64     211     37     54
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
44P52898    323   DDBX_BOVIN Dihydrodiol dehydrogenase 3 OS=Bos...3169e-64     211     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
45P52895    323   AK1C2_HUMAN Aldo-keto reductase family 1 memb...3133e-63     209     39     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047026; F:androsterone dehydrogenase (A-specific) activity; IEA:EC.::GO:0032052; F:bile acid binding; IDA:UniProtKB.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IDA:UniProtKB.
GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0007586; P:digestion; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0034694; P:response to prostaglandin stimulus; IDA:UniProtKB.
46Q8SSK6    301   ALDR_ENCCU Aldose reductase OS=Encephalitozoo...3114e-63     208     39     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:EC.
47P52897    323   PGFS2_BOVIN Prostaglandin F synthase 2 OS=Bos...3184e-63     209     39     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:EC.::GO:0047017; F:prostaglandin-F synthase activity; IEA:EC.
GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW.
48P70694    323   DHB5_MOUSE Estradiol 17 beta-dehydrogenase 5 ...3132e-62     207     38     59
GO:0004033; F:aldo-keto reductase (NADP) activity; IDA:MGI.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:MGI.
GO:0006694; P:steroid biosynthetic process; IDA:MGI.
49Q04828    323   AK1C1_HUMAN Aldo-keto reductase family 1 memb...3135e-62     206     39     58GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IDA:UniProtKB.::GO:0032052; F:bile acid binding; IDA:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IDA:UniProtKB.
GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0015721; P:bile acid and bile salt transport; TAS:UniProtKB.::GO:0008206; P:bile acid metabolic process; IDA:UniProtKB.::GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.::GO:0042632; P:cholesterol homeostasis; TAS:UniProtKB.::GO:0030299; P:intestinal cholesterol absorption; TAS:UniProtKB.::GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.::GO:0051260; P:protein homooligomerization; IDA:UniProtKB.::GO:0046683; P:response to organophosphorus; IEP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; NAS:UniProtKB.
50Q95JH6    323   AK1C1_MACFU Aldo-keto reductase family 1 memb...3141e-61     205     39     59GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB.
GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
51Q95JH7    323   AK1C1_MACFA Aldo-keto reductase family 1 memb...3143e-61     204     39     59GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB.
GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
52Q5REQ0    323   AK1C1_PONAB Aldo-keto reductase family 1 memb...3131e-60     202     38     58GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0047042; F:androsterone dehydrogenase (B-specific) activity; ISS:UniProtKB.::GO:0032052; F:bile acid binding; ISS:UniProtKB.::GO:0047718; F:indanol dehydrogenase activity; IEA:EC.::GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; ISS:UniProtKB.
GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.::GO:0007586; P:digestion; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
53P15121    316   ALDR_HUMAN Aldose reductase OS=Homo sapiens (...3144e-60     201     42     60GO:0005829; C:cytosol; TAS:Reactome.::GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:HPA.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0043795; F:glyceraldehyde oxidoreductase activity; IDA:UniProtKB.
GO:0016999; P:antibiotic metabolic process; IMP:UniProtKB.::GO:0006700; P:C21-steroid hormone biosynthetic process; TAS:Reactome.::GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.::GO:0006950; P:response to stress; TAS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
54P80508    323   PE2R_RABIT Prostaglandin-E(2) 9-reductase OS=...3132e-59     199     39     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:EC.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC.
GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-KW.
55Q6GMC7    327   AK1A1_XENLA Alcohol dehydrogenase [NADP(+)] O...3203e-59     199     40     59
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
56Q28FD1    327   AK1A1_XENTR Alcohol dehydrogenase [NADP(+)] O...3194e-59     199     40     59
GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
57P07943    316   ALDR_RAT Aldose reductase OS=Rattus norvegicu...3145e-59     198     42     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:RGD.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:RGD.
GO:0046427; P:positive regulation of JAK-STAT cascade; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0010033; P:response to organic substance; IDA:RGD.::GO:0006061; P:sorbitol biosynthetic process; IMP:RGD.::GO:0031098; P:stress-activated protein kinase signaling cascade; IMP:RGD.
58Q95JH4    323   AK1C4_MACFU Aldo-keto reductase family 1 memb...3145e-59     198     39     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0047743; F:chlordecone reductase activity; IEA:EC.
59Q95JH5    323   AK1C4_MACFA Aldo-keto reductase family 1 memb...3146e-59     198     39     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IEA:EC.::GO:0047743; F:chlordecone reductase activity; IEA:EC.
60P45376    316   ALDR_MOUSE Aldose reductase OS=Mus musculus (...3146e-59     198     42     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:MGI.
61O80944    311   AKRC8_ARATH Aldo-keto reductase family 4 memb...2842e-58     196     40     56GO:0005829; C:cytosol; IDA:TAIR.
GO:0004033; F:aldo-keto reductase (NADP) activity; IDA:UniProtKB.::GO:0070401; F:NADP+ binding; IDA:UniProtKB.::GO:0016229; F:steroid dehydrogenase activity; IDA:UniProtKB.
GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009651; P:response to salt stress; IEP:UniProtKB.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW.::GO:0009414; P:response to water deprivation; IEP:UniProtKB.
records
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