Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List


UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR102W
Length:
1080
Number of sequences:
5887
Description:
YHR102W KIC1 SGDID:S000001144, Chr VIII from 316572-319814, Genome Release 64-1-1, Verified ORF, "Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
331Q6C3J2    371   IPL1_YARLI Spindle assembly checkpoint kinase...2625e-28     122     31     51GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
332P36507    400   MP2K2_HUMAN Dual specificity mitogen-activate...3036e-28     122     28     46GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005576; C:extracellular region; NAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0070371; P:ERK1 and ERK2 cascade; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
333Q6P4S6    1311   SIK3_MOUSE Serine/threonine-protein kinase SI...2666e-28     126     30     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
334Q54MY9    860   MKCA_DICDI Probable serine/threonine-protein ...2647e-28     125     32     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0045595; P:regulation of cell differentiation; IGI:dictyBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
335Q90891    398   MP2K2_CHICK Dual specificity mitogen-activate...3038e-28     121     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0035419; P:activation of MAPK activity involved in innate immune response; TAS:Reactome.::GO:0070371; P:ERK1 and ERK2 cascade; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0035681; P:toll-like receptor 15 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0035682; P:toll-like receptor 21 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.::GO:0034154; P:toll-like receptor 7 signaling pathway; TAS:Reactome.
336Q60806    631   PLK3_MOUSE Serine/threonine-protein kinase PL...2619e-28     124     28     54GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071779; P:G1/S transition checkpoint; IMP:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0090166; P:Golgi disassembly; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:2000777; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia; ISS:UniProtKB.::GO:0043491; P:protein kinase B signaling cascade; IMP:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IMP:UniProtKB.::GO:0006970; P:response to osmotic stress; ISS:UniProtKB.::GO:0009314; P:response to radiation; ISS:UniProtKB.::GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; ISS:UniProtKB.
337P25323    295   MYLKA_DICDI Myosin light chain kinase A OS=Di...2941e-27     119     29     52GO:0005737; C:cytoplasm; IDA:dictyBase.
GO:0030898; F:actin-dependent ATPase activity; IDA:dictyBase.::GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004687; F:myosin light chain kinase activity; IDA:dictyBase.
GO:0019933; P:cAMP-mediated signaling; IDA:dictyBase.::GO:0019934; P:cGMP-mediated signaling; IDA:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0050920; P:regulation of chemotaxis; IMP:dictyBase.
338O14733    419   MP2K7_HUMAN Dual specificity mitogen-activate...2711e-27     121     30     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004708; F:MAP kinase kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0019903; F:protein phosphatase binding; ISS:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0007257; P:activation of JUN kinase activity; ISS:BHF-UCL.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
339P53351    682   PLK2_MOUSE Serine/threonine-protein kinase PL...2611e-27     124     28     54GO:0005814; C:centriole; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0060292; P:long term synaptic depression; ISS:UniProtKB.::GO:0060291; P:long-term synaptic potentiation; ISS:UniProtKB.::GO:0007613; P:memory; IMP:UniProtKB.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:UniProtKB.::GO:0007052; P:mitotic spindle organization; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.::GO:0046599; P:regulation of centriole replication; ISS:UniProtKB.
340P93759    530   CDPKE_ARATH Calcium-dependent protein kinase ...3071e-27     122     29     50GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
341Q1HG70    400   MP2K2_CANFA Dual specificity mitogen-activate...3031e-27     121     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
342Q0JI49    502   CIPKB_ORYSJ CBL-interacting protein kinase 11...2711e-27     122     30     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
343Q65X23    621   WNK2_ORYSJ Probable serine/threonine-protein ...2771e-27     123     32     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
344P50530    696   SCK1_SCHPO Serine/threonine-protein kinase sc...2741e-27     123     30     50GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IC:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0019933; P:cAMP-mediated signaling; IMP:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IGI:PomBase.::GO:0090062; P:regulation of trehalose metabolic process; IMP:PomBase.
345Q869X3    921   Y9851_DICDI Probable serine/threonine-protein...2582e-27     124     32     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
346Q8W490    470   PEPK2_ARATH Serine/threonine-protein kinase P...2712e-27     121     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
347Q4KSH7    419   MP2K7_RAT Dual specificity mitogen-activated ...2712e-27     120     29     52GO:0005829; C:cytosol; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0008545; F:JUN kinase kinase activity; IDA:RGD.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.
348Q5JLS2    540   CIPKC_ORYSJ CBL-interacting protein kinase 12...2572e-27     122     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
349Q3E9C0    523   CDPKY_ARATH Calcium-dependent protein kinase ...4152e-27     121     26     45GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0080092; P:regulation of pollen tube growth; IMP:TAIR.
350Q12706    436   PSK1_SCHPO Serine/threonine-protein kinase ps...2532e-27     120     32     53GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0007165; P:signal transduction; IC:PomBase.
351P06245    380   KAPB_YEAST cAMP-dependent protein kinase type...2292e-27     120     33     53GO:0005952; C:cAMP-dependent protein kinase complex; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0007265; P:Ras protein signal transduction; ISS:SGD.
352Q755C4    367   IPL1_ASHGO Spindle assembly checkpoint kinase...2642e-27     119     29     55GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
353Q9R012    682   PLK2_RAT Serine/threonine-protein kinase PLK2...2613e-27     122     27     54GO:0005814; C:centriole; ISS:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0060292; P:long term synaptic depression; IDA:UniProtKB.::GO:0060291; P:long-term synaptic potentiation; IDA:UniProtKB.::GO:0007613; P:memory; ISS:UniProtKB.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0007052; P:mitotic spindle organization; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0032486; P:Rap protein signal transduction; IDA:UniProtKB.::GO:0046599; P:regulation of centriole replication; ISS:UniProtKB.
354Q9LT35    416   NEK6_ARATH Serine/threonine-protein kinase Ne...2563e-27     120     30     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
355P53682    534   CDPK1_ORYSJ Calcium-dependent protein kinase ...2723e-27     121     32     52GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
356O94235    678   MPH1_SCHPO Serine/threonine-protein kinase mp...2903e-27     122     27     49GO:0000778; C:condensed nuclear chromosome kinetochore; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005816; C:spindle pole body; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
357Q8MYF1    456   Y2070_DICDI Probable serine/threonine-protein...2603e-27     120     31     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
358Q9LP51    520   CIPKI_ARATH CBL-interacting serine/threonine-...2583e-27     120     29     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
359Q10LQ2    451   CIPKA_ORYSJ CBL-interacting protein kinase 10...2693e-27     120     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
360Q54PB4    481   MYLKE_DICDI Probable myosin light chain kinas...2664e-27     120     31     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:dictyBase.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0007165; P:signal transduction; ISS:dictyBase.
361D3ZHP7    472   ULK3_RAT Serine/threonine-protein kinase ULK3...2654e-27     120     31     52GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
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