Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR102W
Length:
1080
Number of sequences:
5887
Description:
YHR102W KIC1 SGDID:S000001144, Chr VIII from 316572-319814, Genome Release 64-1-1, Verified ORF, "Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q6DE08    361   AUKBA_XENLA Aurora kinase B-A OS=Xenopus laev...2576e-33     136     34     53
212Q9WTR2    1291   M3K6_MOUSE Mitogen-activated protein kinase k...2621e-32     141     37     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
213Q9UQB9    309   AURKC_HUMAN Aurora kinase C OS=Homo sapiens (...2591e-32     134     35     54GO:0032133; C:chromosome passenger complex; TAS:UniProtKB.::GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000793; C:condensed chromosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB.
GO:0008608; P:attachment of spindle microtubules to kinetochore; TAS:UniProtKB.::GO:0000910; P:cytokinesis; TAS:ProtInc.::GO:0016570; P:histone modification; TAS:UniProtKB.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; TAS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; TAS:UniProtKB.
214P49101    513   CDPK2_MAIZE Calcium-dependent protein kinase ...3021e-32     137     32     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
215P28829    659   BYR2_SCHPO Protein kinase byr2 OS=Schizosacch...2791e-32     139     33     53GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005886; C:plasma membrane; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0000751; P:cell cycle arrest in response to pheromone; TAS:PomBase.::GO:0031142; P:induction of conjugation upon nitrogen starvation; TAS:PomBase.::GO:0032005; P:signal transduction involved in conjugation with cellular fusion; TAS:PomBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
216P45985    399   MP2K4_HUMAN Dual specificity mitogen-activate...2742e-32     135     32     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
217Q42438    533   CDPK8_ARATH Calcium-dependent protein kinase ...3122e-32     137     31     51GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
218P33886    605   WIS1_SCHPO Protein kinase wis1 OS=Schizosacch...2672e-32     137     31     51GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; NAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0070301; P:cellular response to hydrogen peroxide; IMP:PomBase.::GO:0071470; P:cellular response to osmotic stress; TAS:PomBase.::GO:0070314; P:G1 to G0 transition; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0043555; P:regulation of translation in response to stress; IMP:PomBase.::GO:0046685; P:response to arsenic-containing substance; IMP:PomBase.::GO:0051403; P:stress-activated MAPK cascade; TAS:PomBase.
219Q55FT4    2247   TSUA_DICDI Probable serine/threonine-protein ...2592e-32     140     32     53GO:0005881; C:cytoplasmic microtubule; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0030010; P:establishment of cell polarity; IMP:dictyBase.::GO:0030837; P:negative regulation of actin filament polymerization; IMP:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0031272; P:regulation of pseudopodium assembly; IMP:dictyBase.
220Q91819    408   AURAB_XENLA Aurora kinase A-B OS=Xenopus laev...2553e-32     135     32     54GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005876; C:spindle microtubule; ISS:UniProtKB.::GO:0000922; C:spindle pole; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019894; F:kinesin binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; ISS:UniProtKB.
221P97477    395   AURKA_MOUSE Aurora kinase A OS=Mus musculus (...2623e-32     135     33     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:MGI.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
222P47809    397   MP2K4_MOUSE Dual specificity mitogen-activate...2683e-32     135     32     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0000165; P:MAPK cascade; IPI:MGI.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
223Q20347    363   MKK4_CAEEL MAP kinase kinase mkk-4 OS=Caenorh...2643e-32     134     33     52GO:0005737; C:cytoplasm; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:WormBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000187; P:activation of MAPK activity; IGI:WormBase.::GO:0050807; P:regulation of synapse organization; IMP:WormBase.
224Q6NW76    320   AURKB_DANRE Aurora kinase B OS=Danio rerio (Z...2564e-32     133     35     55GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007059; P:chromosome segregation; IMP:ZFIN.::GO:0000910; P:cytokinesis; IMP:ZFIN.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
225Q55CE0    677   MKCF_DICDI Probable serine/threonine-protein ...2824e-32     137     35     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
226Q9C6P3    521   CDPKX_ARATH Calcium-dependent protein kinase ...3124e-32     136     31     53GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
227Q10407    1116   MKH1_SCHPO MAP kinase kinase kinase mkh1 OS=S...2767e-32     138     32     51GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0033205; P:cell cycle cytokinesis; NAS:PomBase.::GO:0034605; P:cellular response to heat; IMP:PomBase.::GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0006883; P:cellular sodium ion homeostasis; NAS:PomBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:PomBase.::GO:0031505; P:fungal-type cell wall organization; IMP:PomBase.::GO:0050850; P:positive regulation of calcium-mediated signaling; IMP:PomBase.::GO:0008360; P:regulation of cell shape; NAS:PomBase.
228Q07192    446   MP2K2_XENLA Dual specificity mitogen-activate...3087e-32     134     31     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
229Q9ZSA4    485   CDPKR_ARATH Calcium-dependent protein kinase ...3168e-32     135     32     51GO:0005829; C:cytosol; IDA:TAIR.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
230Q6GPL3    368   AUKBB_XENLA Aurora kinase B-B OS=Xenopus laev...2571e-31     133     33     53GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0032133; C:chromosome passenger complex; ISS:UniProtKB.::GO:0000775; C:chromosome, centromeric region; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035175; F:histone kinase activity (H3-S10 specific); ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
231O95382    1288   M3K6_HUMAN Mitogen-activated protein kinase k...2621e-31     138     37     53
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.
GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.
232Q8TDX7    302   NEK7_HUMAN Serine/threonine-protein kinase Ne...2711e-31     131     33     52GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; TAS:UniProtKB.::GO:0051225; P:spindle assembly; TAS:UniProtKB.
233A5GFW1    402   AURKA_PIG Aurora kinase A OS=Sus scrofa (Pig)...1961e-31     133     38     58GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
234P59241    397   AURKA_RAT Aurora kinase A OS=Rattus norvegicu...2611e-31     133     33     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.
235Q91820    407   AURAA_XENLA Aurora kinase A-A OS=Xenopus laev...2552e-31     133     31     54GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0000922; C:spindle pole; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019894; F:kinesin binding; IPI:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; IMP:UniProtKB.
236Q2TA06    402   AURKA_BOVIN Aurora kinase A OS=Bos taurus (Bo...1962e-31     132     38     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
237O14965    403   AURKA_HUMAN Aurora kinase A OS=Homo sapiens (...1962e-31     132     38     58GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; TAS:UniProtKB.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0005876; C:spindle microtubule; IDA:BHF-UCL.::GO:0031616; C:spindle pole centrosome; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; TAS:ProtInc.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.::GO:0045840; P:positive regulation of mitosis; TAS:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0046605; P:regulation of centrosome cycle; TAS:UniProtKB.::GO:0031647; P:regulation of protein stability; IMP:UniProtKB.::GO:0007051; P:spindle organization; NAS:UniProtKB.
238O49717    554   CDPKF_ARATH Calcium-dependent protein kinase ...3012e-31     134     33     50GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
239A2AQW0    1331   M3K15_MOUSE Mitogen-activated protein kinase ...2573e-31     137     35     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
240D3ZBE5    302   NEK7_RAT Serine/threonine-protein kinase Nek7...2713e-31     130     33     51GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
241Q8W1D5    488   CIPKP_ARATH CBL-interacting serine/threonine-...2863e-31     132     31     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0050832; P:defense response to fungus; IEP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
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