Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR102W
Length:
1080
Number of sequences:
5887
Description:
YHR102W KIC1 SGDID:S000001144, Chr VIII from 316572-319814, Genome Release 64-1-1, Verified ORF, "Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q7L7X3    1001   TAOK1_HUMAN Serine/threonine-protein kinase T...2822e-48     191     38     57GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; NAS:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.
122Q6GPK9    1025   TAOK2_XENLA Serine/threonine-protein kinase T...2825e-48     190     37     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0032874; P:positive regulation of stress-activated MAPK cascade; ISS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; ISS:UniProtKB.
123Q7Z2Y5    1582   NRK_HUMAN Nik-related protein kinase OS=Homo ...2955e-48     191     35     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
124Q9H2K8    898   TAOK3_HUMAN Serine/threonine-protein kinase T...2825e-48     189     39     55GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004860; F:protein kinase inhibitor activity; TAS:ProtInc.::GO:0004674; F:protein serine/threonine kinase activity; IDA:HGNC.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0000165; P:MAPK cascade; IMP:HGNC.::GO:0046329; P:negative regulation of JNK cascade; IDA:HGNC.::GO:0046330; P:positive regulation of JNK cascade; IMP:HGNC.::GO:0046777; P:protein autophosphorylation; IDA:HGNC.
125Q9R0G8    1455   NRK_MOUSE Nik-related protein kinase OS=Mus m...2946e-48     191     34     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0007256; P:activation of JNKK activity; IDA:MGI.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0007567; P:parturition; IMP:MGI.::GO:0060721; P:regulation of spongiotrophoblast cell proliferation; IMP:MGI.
126Q8T2I8    1167   SEPA_DICDI Serine/threonine-protein kinase se...2548e-48     190     41     61GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
127Q55GV3    477   PAKC_DICDI Serine/threonine-protein kinase pa...2791e-47     182     40     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0048365; F:Rac GTPase binding; IPI:dictyBase.
GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:dictyBase.::GO:0031273; P:negative regulation of pseudopodium assembly; IMP:dictyBase.
128B7ZR30    950   STK10_XENLA Serine/threonine-protein kinase 1...2711e-47     188     39     61GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042801; F:polo kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:UniProtKB.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0001556; P:oocyte maturation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
129Q9P286    719   PAK7_HUMAN Serine/threonine-protein kinase PA...2712e-47     185     37     57GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0016049; P:cell growth; TAS:UniProtKB.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:UniProtKB.
130P50527    658   STE20_SCHPO Serine/threonine-protein kinase s...2712e-47     184     36     56GO:0071521; C:Cdc42 GTPase complex; TAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0032488; P:Cdc42 protein signal transduction; IGI:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; TAS:PomBase.::GO:0061161; P:positive regulation of establishment of bipolar cell polarity regulating cell shape; IGI:PomBase.::GO:0071775; P:regulation of cell cycle cytokinesis; IMP:PomBase.::GO:0070507; P:regulation of microtubule cytoskeleton organization; IGI:PomBase.
131Q3ULB5    682   PAK6_MOUSE Serine/threonine-protein kinase PA...2503e-47     184     38     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
132Q8C015    719   PAK7_MOUSE Serine/threonine-protein kinase PA...2713e-47     185     37     57GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.
GO:0006916; P:anti-apoptosis; IDA:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
133D4A280    718   PAK7_RAT Serine/threonine-protein kinase PAK ...2713e-47     184     37     57GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
134Q869N2    852   PAKB_DICDI Serine/threonine-protein kinase pa...2534e-47     186     41     56GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0001891; C:phagocytic cup; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016905; F:myosin heavy chain kinase activity; IDA:dictyBase.::GO:0048365; F:Rac GTPase binding; IPI:dictyBase.
GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.::GO:0006907; P:pinocytosis; IMP:dictyBase.::GO:0050766; P:positive regulation of phagocytosis; IMP:dictyBase.
135Q0IHQ8    951   STK10_XENTR Serine/threonine-protein kinase 1...2714e-47     187     39     60GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
136Q9NQU5    681   PAK6_HUMAN Serine/threonine-protein kinase PA...2534e-47     184     38     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:UniProtKB.
137Q5R8Z4    681   PAK6_PONAB Serine/threonine-protein kinase PA...2534e-47     184     38     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
138Q6DD27    896   TAOK3_XENLA Serine/threonine-protein kinase T...2826e-47     186     38     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0032874; P:positive regulation of stress-activated MAPK cascade; ISS:UniProtKB.
139Q9I9E0    898   TAOK3_CHICK Serine/threonine-protein kinase T...2717e-47     186     40     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:AgBase.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000165; P:MAPK cascade; ISS:AgBase.::GO:0046329; P:negative regulation of JNK cascade; ISS:AgBase.::GO:0046330; P:positive regulation of JNK cascade; ISS:AgBase.::GO:0046777; P:protein autophosphorylation; ISS:AgBase.
140Q7SY52    974   STK10_DANRE Serine/threonine-protein kinase 1...2558e-47     186     40     60GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
141P41892    1062   CDC7_SCHPO Cell division control protein 7 OS...2521e-46     186     40     60GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031028; P:septation initiation signaling cascade; IGI:PomBase.
142O22042    651   M3K3_ARATH Mitogen-activated protein kinase k...2742e-46     182     37     58GO:0048046; C:apoplast; IDA:TAIR.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.
GO:0043622; P:cortical microtubule organization; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.
143Q5R4F3    898   TAOK3_PONAB Serine/threonine-protein kinase T...2852e-46     184     39     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0032874; P:positive regulation of stress-activated MAPK cascade; ISS:UniProtKB.
144Q6ZQ29    1240   TAOK2_MOUSE Serine/threonine-protein kinase T...2827e-46     184     36     57GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; ISS:UniProtKB.
145Q9NGW9    714   MKCB_DICDI Probable serine/threonine-protein ...2618e-46     180     34     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
146Q9JLS3    1235   TAOK2_RAT Serine/threonine-protein kinase TAO...2821e-45     183     36     57GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; ISS:UniProtKB.
147Q9UL54    1235   TAOK2_HUMAN Serine/threonine-protein kinase T...2822e-45     182     36     57GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0000186; P:activation of MAPKK activity; IDA:UniProtKB.::GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0016477; P:cell migration; NAS:UniProtKB.::GO:0048041; P:focal adhesion assembly; IDA:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0006612; P:protein targeting to membrane; NAS:UniProtKB.::GO:0001558; P:regulation of cell growth; NAS:UniProtKB.::GO:0008360; P:regulation of cell shape; IDA:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; IDA:UniProtKB.
148P46549    982   SULU_CAEEL Serine/threonine-protein kinase SU...2793e-45     181     39     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007631; P:feeding behavior; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0043051; P:regulation of pharyngeal pumping; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
149Q5B4Z3    1346   SEPH_EMENI Cytokinesis protein sepH OS=194 / ...2645e-45     181     41     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
150Q9UEW8    545   STK39_HUMAN STE20/SPS1-related proline-alanin...3115e-45     176     32     55GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; NAS:UniProtKB.
GO:0006950; P:response to stress; NAS:UniProtKB.
151O88506    553   STK39_RAT STE20/SPS1-related proline-alanine-...3117e-45     176     32     55GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005856; C:cytoskeleton; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.
GO:0043268; P:positive regulation of potassium ion transport; IMP:RGD.
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