Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR081W
Length:
184
Number of sequences:
5887
Description:
YHR081W LRP1 SGDID:S000001123, Chr VIII from 267538-268092, Genome Release 64-1-1, Verified ORF, "Nuclear exosome-associated nucleic acid binding protein; involved in RNA processing, surveillance, degradation, tethering, and export; homolog of mammalian nuclear matrix protein C1D involved in regulation of DNA repair and recombination"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38801    184   LRP1_YEAST Exosome complex protein LRP1 OS=Sa...1845e-129     367     100     100GO:0000176; C:nuclear exosome (RNase complex); IDA:SGD.
GO:0003690; F:double-stranded DNA binding; IDA:SGD.::GO:0003725; F:double-stranded RNA binding; IDA:SGD.
GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0071039; P:nuclear polyadenylation-dependent CUT catabolic process; IMP:SGD.::GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; IMP:SGD.::GO:0071033; P:nuclear retention of pre-mRNA at the site of transcription; IGI:SGD.::GO:0071051; P:polyadenylation-dependent snoRNA 3'-end processing; IMP:SGD.::GO:0000973; P:posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery; IMP:SGD.::GO:0034475; P:U4 snRNA 3'-end processing; IMP:SGD.::GO:0034476; P:U5 snRNA 3'-end processing; IMP:SGD.
2Q32PE4    141   C1D_BOVIN Nuclear nucleic acid-binding protei...1150.016     37.7     26     52GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3Q13901    141   C1D_HUMAN Nuclear nucleic acid-binding protei...1150.022     37.4     26     52GO:0005739; C:mitochondrion; IDA:HPA.::GO:0000176; C:nuclear exosome (RNase complex); TAS:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0003723; F:RNA binding; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0000460; P:maturation of 5.8S rRNA; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q5RBU4    141   C1D_PONAB Nuclear nucleic acid-binding protei...1150.023     37.4     26     52GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q93063    718   EXT2_HUMAN Exostosin-2 OS=Homo sapiens (Human...770.039     37.7     26     48GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031227; C:intrinsic to endoplasmic reticulum membrane; IEA:InterPro.
GO:0050508; F:glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; IEA:EC.::GO:0042328; F:heparan sulfate N-acetylglucosaminyltransferase activity; NAS:BHF-UCL.::GO:0050509; F:N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity; NAS:BHF-UCL.::GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
GO:0006024; P:glycosaminoglycan biosynthetic process; IDA:BHF-UCL.::GO:0015014; P:heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; IMP:BHF-UCL.::GO:0001503; P:ossification; IMP:BHF-UCL.::GO:0007165; P:signal transduction; TAS:ProtInc.
6Q7TSU0    141   C1D_CRIGR Nuclear nucleic acid-binding protei...900.043     36.6     27     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7O35473    141   C1D_MOUSE Nuclear nucleic acid-binding protei...900.069     35.8     27     54GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:MGI.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0016922; F:ligand-dependent nuclear receptor binding; IDA:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003714; F:transcription corepressor activity; IDA:MGI.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8P70428    718   EXT2_MOUSE Exostosin-2 OS=Mus musculus (Mouse...770.63     34.3     27     45GO:0000139; C:Golgi membrane; IC:BHF-UCL.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031227; C:intrinsic to endoplasmic reticulum membrane; IEA:InterPro.
GO:0050508; F:glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; IC:BHF-UCL.::GO:0042328; F:heparan sulfate N-acetylglucosaminyltransferase activity; IC:BHF-UCL.::GO:0050509; F:N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity; IC:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
GO:0030154; P:cell differentiation; IMP:MGI.::GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; IMP:MGI.::GO:0001707; P:mesoderm formation; IMP:MGI.
9O74469    133   YQC7_SCHPO Exosome complex protein C1739.07 O...660.88     32.7     35     64GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IDA:PomBase.::GO:0000176; C:nuclear exosome (RNase complex); ISS:PomBase.::GO:0005730; C:nucleolus; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:PomBase.::GO:0070651; P:nonfunctional rRNA decay; ISS:PomBase.::GO:0071042; P:nuclear polyadenylation-dependent mRNA catabolic process; ISS:PomBase.::GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; ISS:PomBase.::GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; ISS:PomBase.::GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; ISS:PomBase.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; ISS:PomBase.::GO:0043144; P:snoRNA processing; ISS:PomBase.::GO:0016180; P:snRNA processing; ISS:PomBase.
10Q9Y4B5    1905   CC165_HUMAN Coiled-coil domain-containing pro...1401.2     33.5     24     46
11Q3UHU5    1945   CC165_MOUSE Coiled-coil domain-containing pro...1801.5     33.1     23     44
12Q9P2G9    620   KLHL8_HUMAN Kelch-like protein 8 OS=Homo sapi...632.6     32.3     33     52
13Q5RBK4    746   CLCN5_PONAB H(+)/Cl(-) exchange transporter 5...403.6     32     40     65GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
14P51795    746   CLCN5_HUMAN H(+)/Cl(-) exchange transporter 5...403.6     32     40     65GO:0045177; C:apical part of cell; IDA:UniProtKB.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007588; P:excretion; TAS:ProtInc.
15Q9GKE7    746   CLCN5_PIG H(+)/Cl(-) exchange transporter 5 O...403.9     31.6     40     65GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
GO:0006897; P:endocytosis; ISS:AgBase.
16Q9TTU3    746   CLCN5_RABIT H(+)/Cl(-) exchange transporter 5...404.8     31.6     40     65GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
GO:0006897; P:endocytosis; ISS:AgBase.
17O77783    718   EXT2_BOVIN Exostosin-2 OS=Bos taurus (Bovine)...775.1     31.2     26     43GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0031227; C:intrinsic to endoplasmic reticulum membrane; IEA:InterPro.
GO:0050508; F:glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; IDA:UniProtKB.::GO:0050509; F:N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity; IDA:UniProtKB.
GO:0006044; P:N-acetylglucosamine metabolic process; IDA:UniProtKB.
records
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