UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YHR069C

Length:

359

Number of sequences:

5887

Description:

YHR069C RRP4 SGDID:S000001111, Chr VIII from 234658-233579, Genome Release 64-1-1, reverse complement, Verified ORF, "Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; predicted to contain RNA binding domains; has similarity to human hRrp4p (EXOSC2)"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	A9A5C8	226	ECR1_NITMS Probable exosome complex RNA-bindi...	185	0.00005	47.8	26	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
32	Q9YC02	235	ECR1_AERPE Probable exosome complex RNA-bindi...	172	0.001	43.5	26	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
33	Q7KWX9	237	EXOS3_DICDI Putative exosome complex componen...	88	0.32	36.2	30	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
34	Q9Y3B2	195	EXOS1_HUMAN Exosome complex component CSL4 OS...	133	0.35	35.8	27	48	GO:0005829; C:cytosol; TAS:Reactome.::GO:0000178; C:exosome (RNase complex); IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; NAS:UniProtKB.
									GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
35	Q9DAA6	195	EXOS1_MOUSE Exosome complex component CSL4 OS...	133	0.89	34.3	26	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0005515; F:protein binding; IPI:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
36	Q9NQT5	275	EXOS3_HUMAN Exosome complex component RRP40 O...	34	1.2	34.3	44	59	GO:0000177; C:cytoplasmic exosome (RNase complex); IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0000176; C:nuclear exosome (RNase complex); IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; IMP:UniProtKB.
									GO:0000175; F:3'-5'-exoribonuclease activity; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0071034; P:CUT catabolic process; IMP:UniProtKB.::GO:0045006; P:DNA deamination; IDA:UniProtKB.::GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; IMP:UniProtKB.::GO:0045190; P:isotype switching; ISS:UniProtKB.::GO:0006364; P:rRNA processing; IDA:UniProtKB.
37	O13903	240	RRP40_SCHPO Exosome complex component rrp40 O...	145	1.5	33.9	28	41	GO:0000177; C:cytoplasmic exosome (RNase complex); ISS:PomBase.::GO:0000176; C:nuclear exosome (RNase complex); ISS:PomBase.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:PomBase.::GO:0070651; P:nonfunctional rRNA decay; ISS:PomBase.::GO:0071042; P:nuclear polyadenylation-dependent mRNA catabolic process; ISS:PomBase.::GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; ISS:PomBase.::GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; ISS:PomBase.::GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; ISS:PomBase.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; ISS:PomBase.
38	Q3T0E1	275	EXOS3_BOVIN Exosome complex component RRP40 O...	34	1.6	33.9	44	59	GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
39	Q7TQK4	274	EXOS3_MOUSE Exosome complex component RRP40 O...	34	2.3	33.5	44	59	GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0045190; P:isotype switching; IMP:UniProtKB.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
40	Q58651	469	Y1254_METJA Uncharacterized protein MJ1254 OS...	64	2.4	33.9	36	50	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
41	Q9GYH7	1093	RME6_CAEEL Receptor-mediated endocytosis prot...	53	3.1	33.5	42	53	GO:0045334; C:clathrin-coated endocytic vesicle; IDA:WormBase.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005769; C:early endosome; IDA:WormBase.::GO:0005886; C:plasma membrane; IDA:WormBase.
									GO:0032794; F:GTPase activating protein binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; IPI:WormBase.
									GO:0006897; P:endocytosis; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IGI:WormBase.::GO:0032851; P:positive regulation of Rab GTPase activity; IGI:WormBase.::GO:2000369; P:regulation of clathrin-mediated endocytosis; IMP:WormBase.::GO:0051223; P:regulation of protein transport; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.

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