UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YHR068W

Length:

387

Number of sequences:

5887

Description:

YHR068W DYS1 SGDID:S000001110, Chr VIII from 232133-233296, Genome Release 64-1-1, Verified ORF, "Deoxyhypusine synthase, catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; triggers posttranslational hypusination of translation elongation factor eIF-5A and regulates its intracellular levels; tetrameric"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P38791	387	DHYS_YEAST Deoxyhypusine synthase OS=Saccharo...	387	0	804	100	100	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IDA:SGD.
2	Q6FRN2	385	DHYS_CANGA Deoxyhypusine synthase OS=NRRL Y-6...	384	0	703	85	94
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
3	Q6CNG7	379	DHYS_KLULA Deoxyhypusine synthase OS=1267 / N...	378	0	660	81	92
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
4	Q75EW4	382	DHYS_ASHGO Deoxyhypusine synthase OS=Y-1056) ...	380	0	647	79	90
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
5	Q6BJH5	378	DHYS_DEBHA Deoxyhypusine synthase OS=0083 / I...	378	0	626	78	89
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
6	Q6CG56	346	DHYS_YARLI Deoxyhypusine synthase OS=lipolyti...	370	0	531	70	79
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
7	P49365	353	DHYS_NEUCR Deoxyhypusine synthase OS=1257 / F...	374	1e-158	457	60	74
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
8	Q6AY53	369	DHYS_RAT Deoxyhypusine synthase OS=Rattus nor...	364	9e-147	427	59	74
									GO:0034038; F:deoxyhypusine synthase activity; IDA:RGD.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IDA:RGD.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.::GO:0051289; P:protein homotetramerization; IDA:RGD.
9	O94337	350	DHYS_SCHPO Probable deoxyhypusine synthase OS...	373	2e-146	426	57	73	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0002182; P:cytoplasmic translational elongation; NAS:PomBase.::GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IC:PomBase.::GO:0008612; P:peptidyl-lysine modification to hypusine; ISS:PomBase.::GO:0006448; P:regulation of translational elongation; IC:PomBase.
10	Q3TXU5	369	DHYS_MOUSE Deoxyhypusine synthase OS=Mus musc...	364	2e-146	427	58	74
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
11	P49366	369	DHYS_HUMAN Deoxyhypusine synthase OS=Homo sap...	364	2e-145	424	58	74	GO:0005829; C:cytosol; TAS:Reactome.
									GO:0034038; F:deoxyhypusine synthase activity; TAS:Reactome.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; TAS:ProtInc.::GO:0008612; P:peptidyl-lysine modification to hypusine; TAS:Reactome.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0006412; P:translation; TAS:ProtInc.
12	Q6EWQ6	369	DHYS_BOVIN Deoxyhypusine synthase OS=Bos taur...	373	3e-144	421	57	73
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
13	Q9SC80	379	DHYS_TOBAC Deoxyhypusine synthase OS=Nicotian...	386	9e-141	412	53	70
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
14	Q9AXR0	381	DHYS_SOLLC Deoxyhypusine synthase OS=Solanum ...	382	2e-140	412	54	71
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
15	Q9SC14	371	DHYS_SENVE Deoxyhypusine synthase OS=Senecio ...	376	5e-140	410	55	70
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
16	Q9FI94	368	DHYS_ARATH Deoxyhypusine synthase OS=Arabidop...	356	5e-139	408	56	72
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0009553; P:embryo sac development; IMP:TAIR.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
17	Q9XXJ0	371	DHYS_CAEEL Probable deoxyhypusine synthase OS...	369	8e-139	407	54	71
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
18	Q9VSF4	368	DHYS_DROME Probable deoxyhypusine synthase OS...	386	1e-138	407	51	71
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
19	Q6RJS2	368	DHYS_BRANA Deoxyhypusine synthase OS=Brassica...	375	6e-138	405	54	70
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
20	Q54MQ7	376	DHYS_DICDI Probable deoxyhypusine synthase OS...	372	3e-137	403	54	74
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
21	Q9AXQ8	373	DHYS_DIACA Deoxyhypusine synthase OS=Dianthus...	390	7e-137	402	53	68
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
22	Q9AXQ9	376	DHYS_MUSAC Deoxyhypusine synthase OS=Musa acu...	378	2e-133	394	53	71
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
23	P60038	370	HSS2_SENVE Homospermidine synthase 2 OS=Senec...	386	2e-131	388	52	68
									GO:0050514; F:homospermidine synthase (spermidine-specific) activity; IEA:EC.
									GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:InterPro.
24	Q9M4B0	370	HSS1_SENVU Homospermidine synthase OS=Senecio...	386	2e-130	385	51	67
									GO:0050514; F:homospermidine synthase (spermidine-specific) activity; IEA:EC.
									GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:InterPro.
25	Q9SC13	370	HSS1_SENVE Homospermidine synthase 1 OS=Senec...	386	4e-130	385	51	67
									GO:0050514; F:homospermidine synthase (spermidine-specific) activity; IEA:EC.
									GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:InterPro.
26	Q8U407	336	DHYS_PYRFU Probable deoxyhypusine synthase OS...	359	5e-90	281	41	64
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
27	O50105	342	DHYS_PYRHO Probable deoxyhypusine synthase OS...	362	2e-86	272	41	62
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
28	C5A5L0	336	DHYS_THEGJ Probable deoxyhypusine synthase OS...	333	4e-85	268	41	64
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
29	Q5JEY0	337	DHYS_PYRKO Probable deoxyhypusine synthase OS...	361	5e-85	268	40	61
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
30	Q9V0N5	335	DHYS_PYRAB Probable deoxyhypusine synthase OS...	367	2e-84	266	39	61
									GO:0034038; F:deoxyhypusine synthase activity; IEA:InterPro.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:HAMAP.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.
31	B6YVB1	335	DHYS_THEON Probable deoxyhypusine synthase OS...	362	3e-84	266	40	60
									GO:0034038; F:deoxyhypusine synthase activity; IEA:EC.
									GO:0050983; P:deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase; IEA:EC.::GO:0008612; P:peptidyl-lysine modification to hypusine; IEA:UniProtKB-KW.

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