Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR058C
Length:
295
Number of sequences:
5887
Description:
YHR058C MED6 SGDID:S000001100, Chr VIII from 219884-218997, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38782    295   MED6_YEAST Mediator of RNA polymerase II tran...2950     608     100     100GO:0070847; C:core mediator complex; IDA:SGD.::GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001128; F:RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly; IDA:SGD.
2Q6FW12    302   MED6_CANGA Mediator of RNA polymerase II tran...3105e-99     300     54     66GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
3Q6CTT6    268   MED6_KLULA Mediator of RNA polymerase II tran...2996e-72     229     43     60GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
4Q75EY3    235   MED6_ASHGO Mediator of RNA polymerase II tran...2955e-70     223     43     56GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
5Q6C3T0    227   MED6_YARLI Mediator of RNA polymerase II tran...1999e-42     149     41     55GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
6Q6BIH7    257   MED6_DEBHA Mediator of RNA polymerase II tran...2958e-38     140     34     49GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
7Q5A2Z1    263   MED6_CANAL Mediator of RNA polymerase II tran...1966e-36     135     37     54GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
8A3LQ10    263   MED6_PICST Mediator of RNA polymerase II tran...2013e-26     108     38     56GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
9Q9US45    216   MED6_SCHPO Mediator of RNA polymerase II tran...2142e-24     102     29     46GO:0016592; C:mediator complex; IDA:PomBase.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
10Q5AYT1    325   MED6_EMENI Mediator of RNA polymerase II tran...2214e-20     91.7     29     43GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
11A2R4I0    323   MED6_ASPNC Mediator of RNA polymerase II tran...2174e-20     91.7     29     43GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
12Q2U9E7    328   MED6_ASPOR Mediator of RNA polymerase II tran...2246e-20     91.3     29     43GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
13Q9HED8    360   MED6_NEUCR Mediator of RNA polymerase II tran...2727e-20     91.3     28     45GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
14Q0CH76    324   MED6_ASPTN Mediator of RNA polymerase II tran...2227e-19     88.2     28     42GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
15Q7Q107    267   MED6_ANOGA Mediator of RNA polymerase II tran...2103e-18     85.9     26     41GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
16Q4PHA6    254   MED6_USTMA Mediator of RNA polymerase II tran...1984e-18     85.1     31     45GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
17Q4WDH9    324   MED6_ASPFU Mediator of RNA polymerase II tran...2175e-18     85.9     28     43GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
18Q3SZY9    246   MED6_BOVIN Mediator of RNA polymerase II tran...1998e-18     84.3     28     46
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
19Q5RD94    246   MED6_PONAB Mediator of RNA polymerase II tran...1998e-18     84     28     46GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
20Q921D4    246   MED6_MOUSE Mediator of RNA polymerase II tran...1999e-18     84     28     46GO:0016592; C:mediator complex; IDA:MGI.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
21O75586    246   MED6_HUMAN Mediator of RNA polymerase II tran...1991e-17     84     28     46GO:0016592; C:mediator complex; IMP:UniProtKB.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.::GO:0003713; F:transcription coactivator activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
22Q6IQ63    254   MED6_DANRE Mediator of RNA polymerase II tran...1990.000000000000001     78.2     27     44GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
23Q8MSX2    249   MED6_DROME Mediator of RNA polymerase II tran...1250.00000000000005     73.2     30     52GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0016592; C:mediator complex; IMP:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001104; F:RNA polymerase II transcription cofactor activity; IMP:UniProtKB.
24Q54PN3    267   MED6_DICDI Putative mediator of RNA polymeras...1890.000000000001     69.7     26     41GO:0016592; C:mediator complex; ISS:dictyBase.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
GO:0006367; P:transcription initiation from RNA polymerase II promoter; IC:dictyBase.
25Q1E3Z7    358   MED6_COCIM Mediator of RNA polymerase II tran...1760.0000000004     63.5     27     44GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
26P0CO74    357   MED6_CRYNJ Mediator of RNA polymerase II tran...1920.000000002     61.6     23     41GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
27P0CO75    357   MED6_CRYNB Mediator of RNA polymerase II tran...1920.000000002     61.6     23     41GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
28Q9N337    250   MED6_CAEEL Mediator of RNA polymerase II tran...1980.00000005     56.6     24     42GO:0016592; C:mediator complex; IEA:InterPro.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0007283; P:spermatogenesis; IMP:WormBase.
29Q8SWN5    177   MED6_ENCCU Mediator of RNA polymerase II tran...1720.00000005     55.1     26     40GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
30Q60WM1    246   MED6_CAEBR Mediator of RNA polymerase II tran...1970.0000003     53.9     23     42GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
31P50059    206   SODM2_PLEBO Superoxide dismutase [Mn] 2 OS=Pl...1191.1     33.9     30     40
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004784; F:superoxide dismutase activity; IEA:EC.
GO:0006801; P:superoxide metabolic process; IEA:InterPro.
records
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