UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YHR039C-A

Length:

114

Number of sequences:

5887

Description:

YHR039C-A VMA10 SGDID:S000002100, Chr VIII from 187514-187173,187679-187677, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit G of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; involved in vacuolar acidification"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P48836	114	VATG_YEAST V-type proton ATPase subunit G OS=...	114	1e-72	218	100	100	GO:0000221; C:vacuolar proton-transporting V-type ATPase, V1 domain; IDA:SGD.
									GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; TAS:SGD.
									GO:0007035; P:vacuolar acidification; TAS:SGD.
2	P78713	115	VATG_NEUCR V-type proton ATPase subunit G OS=...	103	0.000000000000002	71.6	41	65	GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0015992; P:proton transport; IEA:UniProtKB-KW.
3	Q25532	117	VATG_MANSE V-type proton ATPase subunit G OS=...	111	0.00000000000003	68.6	38	63	GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0015992; P:proton transport; IEA:UniProtKB-KW.
4	Q9XZH6	117	VATG_DROME V-type proton ATPase subunit G OS=...	111	0.00000000000004	68.2	37	63	GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0015992; P:proton transport; IEA:UniProtKB-KW.
5	Q9CR51	118	VATG1_MOUSE V-type proton ATPase subunit G 1 ...	111	0.00000000000004	68.2	38	57	GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005765; C:lysosomal membrane; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IPI:MGI.
									GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IDA:MGI.
6	P79251	118	VATG1_BOVIN V-type proton ATPase subunit G 1 ...	111	0.00000000000006	67.4	37	57	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
7	O75348	118	VATG1_HUMAN V-type proton ATPase subunit G 1 ...	111	0.00000000000008	67.4	38	56	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
									GO:0051117; F:ATPase binding; IPI:UniProtKB.
									GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0033572; P:transferrin transport; TAS:Reactome.
8	Q96LB4	118	VATG3_HUMAN V-type proton ATPase subunit G 3 ...	111	0.000000000001	64.3	36	55	GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0051117; F:ATPase binding; IPI:UniProtKB.::GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0015992; P:proton transport; IEA:UniProtKB-KW.::GO:0033572; P:transferrin transport; TAS:Reactome.
9	Q9WTT4	118	VATG2_MOUSE V-type proton ATPase subunit G 2 ...	111	0.00000000002	60.8	32	57	GO:0030285; C:integral to synaptic vesicle membrane; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IPI:MGI.
									GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.
10	Q9TSV6	118	VATG2_PIG V-type proton ATPase subunit G 2 OS...	111	0.00000000003	60.5	32	56	GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
11	Q5TM18	118	VATG2_MACMU V-type proton ATPase subunit G 2 ...	111	0.00000000003	60.1	32	56	GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0015992; P:proton transport; IEA:UniProtKB-KW.
12	Q1XHY9	118	VATG2_PANTR V-type proton ATPase subunit G 2 ...	111	0.00000000004	59.7	32	55	GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0015992; P:proton transport; IEA:UniProtKB-KW.
13	Q862Z6	118	VATG1_PANTR V-type proton ATPase subunit G 1 ...	111	0.00000000004	59.7	32	55	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0015992; P:proton transport; IEA:UniProtKB-KW.
14	O95670	118	VATG2_HUMAN V-type proton ATPase subunit G 2 ...	111	0.00000000005	59.7	32	55	GO:0005829; C:cytosol; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0015992; P:proton transport; IEA:UniProtKB-KW.::GO:0033572; P:transferrin transport; TAS:Reactome.
15	Q5WR09	118	VATG1_CANFA V-type proton ATPase subunit G 1 ...	111	0.00000000005	59.3	32	56	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
16	Q617N0	126	VATG_CAEBR Probable V-type proton ATPase subu...	111	0.00000000008	59.3	35	56	GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0012501; P:programmed cell death; ISS:UniProtKB.::GO:0015992; P:proton transport; IEA:UniProtKB-KW.
17	P91303	126	VATG_CAEEL Probable V-type proton ATPase subu...	111	0.00000000008	58.9	35	56	GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; NAS:UniProtKB.
									GO:0015078; F:hydrogen ion transmembrane transporter activity; NAS:UniProtKB.::GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0006754; P:ATP biosynthetic process; NAS:UniProtKB.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0070265; P:necrotic cell death; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0043068; P:positive regulation of programmed cell death; IGI:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
18	Q54Z13	107	VATG_DICDI V-type proton ATPase subunit G OS=...	103	0.0000000001	58.5	39	55	GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0000221; C:vacuolar proton-transporting V-type ATPase, V1 domain; ISS:dictyBase.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0015992; P:proton transport; IEA:UniProtKB-KW.::GO:0007035; P:vacuolar acidification; ISS:dictyBase.
19	Q8BMC1	118	VATG3_MOUSE V-type proton ATPase subunit G 3 ...	111	0.000000001	55.8	33	53	GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IDA:MGI.
									GO:0015991; P:ATP hydrolysis coupled proton transport; IC:MGI.
20	Q5XGW0	118	VATG3_XENLA V-type proton ATPase subunit G 3 ...	111	0.00000002	52.4	31	52	GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0015992; P:proton transport; IEA:InterPro.
21	Q9SP55	110	VATG_CITLI V-type proton ATPase subunit G OS=...	99	0.00000003	51.6	35	59	GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0015992; P:proton transport; IEA:UniProtKB-KW.
22	A4QNE9	118	VATG3_XENTR V-type proton ATPase subunit G 3 ...	111	0.00000004	51.2	30	52	GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0015992; P:proton transport; IEA:InterPro.
23	O74174	108	VATG_SCHPO V-type proton ATPase subunit G OS=...	95	0.00000005	50.8	38	62	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0000221; C:vacuolar proton-transporting V-type ATPase, V1 domain; ISS:PomBase.
									GO:0005524; F:ATP binding; IC:PomBase.::GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0015991; P:ATP hydrolysis coupled proton transport; IC:PomBase.::GO:0007035; P:vacuolar acidification; ISS:PomBase.
24	O82702	110	VATG1_TOBAC V-type proton ATPase subunit G 1 ...	101	0.000002	46.6	37	57	GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0015992; P:proton transport; IEA:UniProtKB-KW.
25	O82629	106	VATG2_ARATH V-type proton ATPase subunit G2 O...	97	0.000003	45.8	32	55	GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0015992; P:proton transport; IEA:UniProtKB-KW.
26	Q9SZH0	108	VATG3_ARATH V-type proton ATPase subunit G3 O...	105	0.00001	43.9	32	58	GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0015992; P:proton transport; IEA:UniProtKB-KW.
27	O82703	111	VATG2_TOBAC V-type proton ATPase subunit G 2 ...	99	0.00003	42.7	35	57	GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0015992; P:proton transport; IEA:UniProtKB-KW.
28	O82628	110	VAGT1_ARATH V-type proton ATPase subunit G1 O...	97	0.006	36.6	35	57	GO:0005829; C:cytosol; IDA:TAIR.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0016471; C:vacuolar proton-transporting V-type ATPase complex; IEA:InterPro.
									GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
									GO:0015992; P:proton transport; IEA:UniProtKB-KW.
29	P12755	728	SKI_HUMAN Ski oncogene OS=Homo sapiens (Human...	92	2.2	30.8	25	53	GO:0005737; C:cytoplasm; ISS:BHF-UCL.::GO:0016605; C:PML body; IDA:UniProtKB.::GO:0005667; C:transcription factor complex; ISS:BHF-UCL.::GO:0017053; C:transcriptional repressor complex; ISS:BHF-UCL.
									GO:0046811; F:histone deacetylase inhibitor activity; ISS:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0070491; F:repressing transcription factor binding; IPI:UniProtKB.::GO:0046332; F:SMAD binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0016564; F:transcription repressor activity; IBA:RefGenome.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
									GO:0009948; P:anterior/posterior axis specification; ISS:BHF-UCL.::GO:0030509; P:BMP signaling pathway; TAS:Reactome.::GO:0060349; P:bone morphogenesis; ISS:BHF-UCL.::GO:0048870; P:cell motility; NAS:BHF-UCL.::GO:0008283; P:cell proliferation; NAS:BHF-UCL.::GO:0030326; P:embryonic limb morphogenesis; ISS:BHF-UCL.::GO:0060325; P:face morphogenesis; ISS:BHF-UCL.::GO:0002089; P:lens morphogenesis in camera-type eye; ISS:BHF-UCL.::GO:0022011; P:myelination in peripheral nervous system; ISS:BHF-UCL.::GO:0014902; P:myotube differentiation; IDA:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; IDA:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; IDA:UniProtKB.::GO:0048147; P:negative regulation of fibroblast proliferation; ISS:BHF-UCL.::GO:0045668; P:negative regulation of osteoblast differentiation; IDA:UniProtKB.::GO:0010626; P:negative regulation of Schwann cell proliferation; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0001843; P:neural tube closure; ISS:BHF-UCL.::GO:0043585; P:nose morphogenesis; ISS:BHF-UCL.::GO:0021772; P:olfactory bulb development; ISS:BHF-UCL.::GO:0060021; P:palate development; ISS:BHF-UCL.::GO:0043388; P:positive regulation of DNA binding; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; NAS:BHF-UCL.::GO:0070207; P:protein homotrimerization; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; ISS:BHF-UCL.::GO:0060041; P:retina development in camera-type eye; ISS:BHF-UCL.::GO:0048741; P:skeletal muscle fiber development; ISS:BHF-UCL.::GO:0060395; P:SMAD protein signal transduction; IDA:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; ISS:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; ISS:BHF-UCL.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; NAS:BHF-UCL.
30	Q96NL6	688	SCLT1_HUMAN Sodium channel and clathrin linke...	41	3.8	30	39	71	GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.
31	Q9TUG2	730	SKI_HORSE Ski oncogene OS=Equus caballus (Hor...	92	5	30	24	52	GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0046332; F:SMAD binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
									GO:0032926; P:negative regulation of activin receptor signaling pathway; ISS:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.::GO:0043388; P:positive regulation of DNA binding; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB.

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