Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR037W
Length:
575
Number of sequences:
5887
Description:
YHR037W PUT2 SGDID:S000001079, Chr VIII from 181977-183704, Genome Release 64-1-1, Verified ORF, "Delta-1-pyrroline-5-carboxylate dehydrogenase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; deficiency of the human homolog causes HPII, an autosomal recessive inborn error of metabolism"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q8HYE4    501   AL1A1_MACFA Retinal dehydrogenase 1 OS=Macaca...5036e-42     162     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001758; F:retinal dehydrogenase activity; IEA:EC.
62O93344    518   AL1A2_CHICK Retinal dehydrogenase 2 OS=Gallus...5164e-41     159     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001758; F:retinal dehydrogenase activity; IEA:EC.
63Q8MI17    496   AL1A1_RABIT Retinal dehydrogenase 1 OS=Orycto...5037e-41     159     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001758; F:retinal dehydrogenase activity; IEA:EC.
64Q9JHW9    512   AL1A3_MOUSE Aldehyde dehydrogenase family 1 m...4781e-40     158     29     47GO:0005737; C:cytoplasm; IDA:MGI.
GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; TAS:MGI.::GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IDA:MGI.::GO:0004030; F:aldehyde dehydrogenase [NAD(P)+ activity; IDA:MGI.::GO:0070403; F:NAD+ binding; IDA:MGI.::GO:0070324; F:thyroid hormone binding; IPI:MGI.
GO:0060324; P:face development; IGI:MGI.::GO:0021768; P:nucleus accumbens development; IMP:MGI.::GO:0060166; P:olfactory pit development; IMP:MGI.::GO:0002072; P:optic cup morphogenesis involved in camera-type eye development; IGI:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0002138; P:retinoic acid biosynthetic process; IDA:MGI.]
65Q25417    498   ALDH2_LEITA Aldehyde dehydrogenase, mitochond...5142e-40     157     29     47GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
66Q8K4D8    512   AL1A3_RAT Aldehyde dehydrogenase family 1 mem...4752e-40     157     29     47GO:0005829; C:cytosol; NAS:RGD.
GO:0004030; F:aldehyde dehydrogenase [NAD(P)+ activity; IDA:RGD.
GO:0001822; P:kidney development; IEP:RGD.::GO:0021983; P:pituitary gland development; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.]
67P24549    501   AL1A1_MOUSE Retinal dehydrogenase 1 OS=Mus mu...5022e-40     157     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; IDA:MGI.::GO:0001758; F:retinal dehydrogenase activity; IEA:EC.
GO:0042904; P:9-cis-retinoic acid biosynthetic process; IDA:MGI.::GO:0002072; P:optic cup morphogenesis involved in camera-type eye development; IGI:MGI.::GO:0043065; P:positive regulation of apoptotic process; IGI:MGI.::GO:0042493; P:response to drug; IDA:MGI.::GO:0042572; P:retinol metabolic process; IMP:MGI.
68O94788    518   AL1A2_HUMAN Retinal dehydrogenase 2 OS=Homo s...5003e-40     157     30     47GO:0005634; C:nucleus; IDA:HPA.
GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; ISS:UniProtKB.::GO:0016918; F:retinal binding; ISS:UniProtKB.::GO:0001758; F:retinal dehydrogenase activity; ISS:UniProtKB.
GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0021915; P:neural tube development; IMP:UniProtKB.::GO:0034097; P:response to cytokine stimulus; IDA:UniProtKB.
69P15437    500   AL1A1_HORSE Retinal dehydrogenase 1 OS=Equus ...4964e-40     156     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001758; F:retinal dehydrogenase activity; IEA:EC.
70P48644    501   AL1A1_BOVIN Retinal dehydrogenase 1 OS=Bos ta...4976e-40     156     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001758; F:retinal dehydrogenase activity; IEA:EC.
71P51977    501   AL1A1_SHEEP Retinal dehydrogenase 1 OS=Ovis a...4978e-40     155     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001758; F:retinal dehydrogenase activity; IEA:EC.
72O35945    501   AL1A7_MOUSE Aldehyde dehydrogenase, cytosolic...4971e-39     155     30     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.
73P86886    500   AL1A1_MESAU Retinal dehydrogenase 1 OS=Mesocr...5311e-39     155     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001758; F:retinal dehydrogenase activity; IEA:EC.
74Q63639    518   AL1A2_RAT Retinal dehydrogenase 2 OS=Rattus n...5141e-39     155     30     47GO:0005829; C:cytosol; IDA:RGD.
GO:0016918; F:retinal binding; IDA:RGD.::GO:0001758; F:retinal dehydrogenase activity; IDA:RGD.
GO:0001822; P:kidney development; IEP:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0007494; P:midgut development; IEP:RGD.::GO:0021983; P:pituitary gland development; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.
75B7VQ28    486   BETB_VIBSL Betaine aldehyde dehydrogenase OS=...5172e-39     154     27     47
GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
GO:0006578; P:betaine biosynthetic process; IEA:InterPro.
76Q62148    518   AL1A2_MOUSE Retinal dehydrogenase 2 OS=Mus mu...5142e-39     154     30     47
GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; IDA:MGI.::GO:0001758; F:retinal dehydrogenase activity; IDA:MGI.
GO:0042904; P:9-cis-retinoic acid biosynthetic process; IDA:MGI.::GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.::GO:0001568; P:blood vessel development; IMP:MGI.::GO:0071300; P:cellular response to retinoic acid; IEP:UniProtKB.::GO:0031076; P:embryonic camera-type eye development; IGI:MGI.::GO:0048566; P:embryonic digestive tract development; IMP:MGI.::GO:0035115; P:embryonic forelimb morphogenesis; IMP:MGI.::GO:0060324; P:face development; IMP:MGI.::GO:0001947; P:heart looping; TAS:DFLAT.::GO:0030902; P:hindbrain development; IMP:MGI.::GO:0030324; P:lung development; IMP:MGI.::GO:0016331; P:morphogenesis of embryonic epithelium; IMP:MGI.::GO:0014032; P:neural crest cell development; IMP:MGI.::GO:0030182; P:neuron differentiation; IMP:MGI.::GO:0031016; P:pancreas development; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI.::GO:0010628; P:positive regulation of gene expression; IMP:MGI.::GO:0009954; P:proximal/distal pattern formation; IMP:MGI.::GO:0001936; P:regulation of endothelial cell proliferation; IMP:MGI.::GO:0042574; P:retinal metabolic process; IDA:MGI.::GO:0048384; P:retinoic acid receptor signaling pathway; IMP:MGI.::GO:0035799; P:ureter maturation; IMP:MGI.
77O34660    495   ALDH4_BACSU Putative aldehyde dehydrogenase d...4762e-39     154     27     46
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.
78P41751    497   ALDH_ASPNG Aldehyde dehydrogenase OS=Aspergil...4853e-39     154     29     47
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.
79P81178    500   ALDH2_MESAU Aldehyde dehydrogenase, mitochond...4894e-39     154     28     46GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.
80P11884    519   ALDH2_RAT Aldehyde dehydrogenase, mitochondri...4894e-39     154     28     45GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IDA:RGD.::GO:0042802; F:identical protein binding; IDA:RGD.
GO:0071398; P:cellular response to fatty acid; IEP:RGD.::GO:0032870; P:cellular response to hormone stimulus; IEP:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0055093; P:response to hyperoxia; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0035094; P:response to nicotine; IEP:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.
81Q9I8W8    517   AL1A2_TAEGU Retinal dehydrogenase 2 OS=Taenio...5165e-39     153     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001758; F:retinal dehydrogenase activity; IEA:EC.
82P40047    520   ALDH5_YEAST Aldehyde dehydrogenase 5, mitocho...4617e-39     153     29     48GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.::GO:0033721; F:aldehyde dehydrogenase (NADP+) activity; IEA:EC.::GO:0004030; F:aldehyde dehydrogenase [NAD(P)+ activity; IDA:SGD.
GO:0019413; P:acetate biosynthetic process; IMP:SGD.]
83A6ZR27    520   ALDH5_YEAS7 Aldehyde dehydrogenase 5, mitocho...4617e-39     153     29     48GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.::GO:0033721; F:aldehyde dehydrogenase (NADP+) activity; IEA:EC.
84A7N2Q0    486   BETB_VIBHB Betaine aldehyde dehydrogenase OS=...5001e-38     152     28     46
GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
GO:0006578; P:betaine biosynthetic process; IEA:InterPro.
85P42329    488   ALDH_GEOSE Aldehyde dehydrogenase, thermostab...4851e-38     152     27     45
GO:0004030; F:aldehyde dehydrogenase [NAD(P)+ activity; IEA:EC.]
86P47738    519   ALDH2_MOUSE Aldehyde dehydrogenase, mitochond...4911e-38     152     27     45GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.
87Q8S528    534   AL2B7_ARATH Aldehyde dehydrogenase family 2 m...4821e-38     152     28     45GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.
88Q2XQV4    521   ALDH2_PIG Aldehyde dehydrogenase, mitochondri...4921e-38     152     28     46GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:EC.
89P95629    1224   PUTA_RHIML Bifunctional protein putA OS=Rhizo...4731e-38     156     30     45
GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; IEA:EC.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004657; F:proline dehydrogenase activity; IEA:EC.
GO:0006537; P:glutamate biosynthetic process; IEA:InterPro.::GO:0006561; P:proline biosynthetic process; IEA:InterPro.::GO:0006562; P:proline catabolic process; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
90P13601    501   AL1A7_RAT Aldehyde dehydrogenase, cytosolic 1...4972e-38     151     30     47GO:0005829; C:cytosol; NAS:RGD.
GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; IDA:RGD.::GO:0018479; F:benzaldehyde dehydrogenase (NAD+) activity; IDA:RGD.::GO:0042802; F:identical protein binding; IDA:RGD.
GO:0035106; P:operant conditioning; IEP:RGD.::GO:0051289; P:protein homotetramerization; IDA:RGD.
91P51647    501   AL1A1_RAT Retinal dehydrogenase 1 OS=Rattus n...4972e-38     151     29     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; TAS:RGD.::GO:0018479; F:benzaldehyde dehydrogenase (NAD+) activity; IDA:RGD.::GO:0042802; F:identical protein binding; IDA:RGD.::GO:0001758; F:retinal dehydrogenase activity; IDA:RGD.
GO:0060206; P:estrous cycle phase; IEP:RGD.::GO:0001822; P:kidney development; IEP:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0007494; P:midgut development; IEP:RGD.::GO:0051289; P:protein homotetramerization; IDA:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IDA:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0006979; P:response to oxidative stress; IMP:RGD.::GO:0032526; P:response to retinoic acid; IEP:RGD.
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