Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR037W
Length:
575
Number of sequences:
5887
Description:
YHR037W PUT2 SGDID:S000001079, Chr VIII from 181977-183704, Genome Release 64-1-1, Verified ORF, "Delta-1-pyrroline-5-carboxylate dehydrogenase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; deficiency of the human homolog causes HPII, an autosomal recessive inborn error of metabolism"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181P46367    519   ALDH4_YEAST Potassium-activated aldehyde dehy...4517e-31     129     27     47GO:0042645; C:mitochondrial nucleoid; IDA:SGD.
GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IDA:SGD.::GO:0004030; F:aldehyde dehydrogenase [NAD(P)+ activity; IDA:SGD.
GO:0019413; P:acetate biosynthetic process; IGI:SGD.::GO:0006067; P:ethanol metabolic process; IMP:SGD.::GO:0006740; P:NADPH regeneration; IGI:SGD.::GO:0006090; P:pyruvate metabolic process; IMP:SGD.]
182B7LQ46    492   ASTD_ESCF3 N-succinylglutamate 5-semialdehyde...4907e-31     129     29     46
GO:0043824; F:succinylglutamate-semialdehyde dehydrogenase activity; IEA:EC.
GO:0006527; P:arginine catabolic process; IEA:InterPro.
183B1JSQ9    490   BETB_YERPY Betaine aldehyde dehydrogenase OS=...5057e-31     129     25     42
GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
GO:0006578; P:betaine biosynthetic process; IEA:InterPro.
184B2HV80    490   BETB_ACIBC Betaine aldehyde dehydrogenase OS=...5158e-31     129     25     44
GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
GO:0006578; P:betaine biosynthetic process; IEA:InterPro.
185P94428    462   GABD_BACSU Succinate-semialdehyde dehydrogena...4819e-31     128     26     44
GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
186Q5E2G9    485   ASTD_VIBF1 N-succinylglutamate 5-semialdehyde...4709e-31     129     28     48
GO:0043824; F:succinylglutamate-semialdehyde dehydrogenase activity; IEA:EC.
GO:0006527; P:arginine catabolic process; IEA:InterPro.
187Q8FH01    492   ASTD_ECOL6 N-succinylglutamate 5-semialdehyde...4891e-30     128     28     46
GO:0043824; F:succinylglutamate-semialdehyde dehydrogenase activity; IEA:EC.
GO:0006527; P:arginine catabolic process; IEA:InterPro.
188Q6GNL7    902   AL1L1_XENLA Cytosolic 10-formyltetrahydrofola...4911e-30     130     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016155; F:formyltetrahydrofolate dehydrogenase activity; IEA:EC.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0009258; P:10-formyltetrahydrofolate catabolic process; IEA:InterPro.::GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
189A4W9J7    495   ASTD_ENT38 N-succinylglutamate 5-semialdehyde...4892e-30     128     28     45
GO:0043824; F:succinylglutamate-semialdehyde dehydrogenase activity; IEA:EC.
GO:0006527; P:arginine catabolic process; IEA:InterPro.
190Q9UTM8    493   SSDH2_SCHPO Putative succinate-semialdehyde d...4862e-30     127     26     44GO:0005829; C:cytosol; IDA:PomBase.
GO:0009013; F:succinate-semialdehyde dehydrogenase [NAD(P)+ activity; ISS:PomBase.
GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006538; P:glutamate catabolic process; ISS:PomBase.]
191Q0TH84    492   ASTD_ECOL5 N-succinylglutamate 5-semialdehyde...4892e-30     127     29     46
GO:0043824; F:succinylglutamate-semialdehyde dehydrogenase activity; IEA:EC.
GO:0006527; P:arginine catabolic process; IEA:InterPro.
192C3K3D2    490   BETB_PSEFS Betaine aldehyde dehydrogenase OS=...5072e-30     127     26     44
GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
GO:0006578; P:betaine biosynthetic process; IEA:InterPro.
193Q92EQ7    488   IOLA_LISIN Methylmalonate semialdehyde dehydr...4612e-30     127     26     44
GO:0018478; F:malonate-semialdehyde dehydrogenase (acetylating) activity; IEA:EC.::GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating) activity; IEA:EC.
194Q5KYK0    484   IOLA3_GEOKA Methylmalonate semialdehyde dehyd...4433e-30     127     28     46
GO:0018478; F:malonate-semialdehyde dehydrogenase (acetylating) activity; IEA:EC.::GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating) activity; IEA:EC.
195B0VST2    490   BETB_ACIBS Betaine aldehyde dehydrogenase OS=...5143e-30     127     25     45
GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
GO:0006578; P:betaine biosynthetic process; IEA:InterPro.
196B2K8U5    490   BETB_YERPB Betaine aldehyde dehydrogenase OS=...5153e-30     127     26     43
GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
GO:0006578; P:betaine biosynthetic process; IEA:InterPro.
197A4XPI6    490   BETB_PSEMY Betaine aldehyde dehydrogenase OS=...4933e-30     127     26     44
GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
GO:0006578; P:betaine biosynthetic process; IEA:InterPro.
198B0KN18    490   BETB_PSEPG Betaine aldehyde dehydrogenase OS=...5104e-30     127     25     44
GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
GO:0006578; P:betaine biosynthetic process; IEA:InterPro.
199A7ZAI1    487   IOLA_BACA2 Methylmalonate semialdehyde dehydr...4634e-30     127     27     42
GO:0018478; F:malonate-semialdehyde dehydrogenase (acetylating) activity; IEA:EC.::GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating) activity; IEA:EC.
200Q8K009    923   AL1L2_MOUSE Mitochondrial 10-formyltetrahydro...5034e-30     129     27     46GO:0005739; C:mitochondrion; IDA:MGI.
GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016155; F:formyltetrahydrofolate dehydrogenase activity; IEA:EC.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
GO:0009258; P:10-formyltetrahydrofolate catabolic process; IEA:InterPro.::GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
201B9JBA3    487   BETB_AGRRK Betaine aldehyde dehydrogenase OS=...4834e-30     127     26     44
GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
GO:0006578; P:betaine biosynthetic process; IEA:InterPro.
202A6W2P7    485   BETB_MARMS Betaine aldehyde dehydrogenase OS=...5025e-30     126     25     43
GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
GO:0006578; P:betaine biosynthetic process; IEA:InterPro.
203P49189    494   AL9A1_HUMAN 4-trimethylaminobutyraldehyde deh...4775e-30     127     26     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0033737; F:1-pyrroline dehydrogenase activity; IEA:EC.::GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; TAS:Reactome.::GO:0047105; F:4-trimethylammoniobutyraldehyde dehydrogenase activity; IEA:EC.::GO:0019145; F:aminobutyraldehyde dehydrogenase activity; IDA:UniProtKB.
GO:0045329; P:carnitine biosynthetic process; TAS:Reactome.::GO:0006081; P:cellular aldehyde metabolic process; IDA:UniProtKB.::GO:0042445; P:hormone metabolic process; TAS:UniProtKB.::GO:0042136; P:neurotransmitter biosynthetic process; IDA:UniProtKB.
204B7NT31    492   ASTD_ECO7I N-succinylglutamate 5-semialdehyde...4955e-30     126     28     46
GO:0043824; F:succinylglutamate-semialdehyde dehydrogenase activity; IEA:EC.
GO:0006527; P:arginine catabolic process; IEA:InterPro.
205P25553    479   ALDA_ECOLI Lactaldehyde dehydrogenase OS=Esch...4936e-30     126     24     46
GO:0050569; F:glycolaldehyde dehydrogenase activity; IDA:EcoCyc.::GO:0008911; F:lactaldehyde dehydrogenase activity; IDA:EcoCyc.
GO:0019571; P:D-arabinose catabolic process; NAS:EcoCyc.::GO:0042355; P:L-fucose catabolic process; IEP:EcoCyc.::GO:0019301; P:rhamnose catabolic process; IMP:EcoCyc.
206A3M365    490   BETB_ACIBT Betaine aldehyde dehydrogenase OS=...5156e-30     126     25     44
GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
GO:0006578; P:betaine biosynthetic process; IEA:InterPro.
207P42412    487   IOLA_BACSU Methylmalonate semialdehyde dehydr...4616e-30     126     27     44
GO:0018478; F:malonate-semialdehyde dehydrogenase (acetylating) activity; IEA:EC.::GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating) activity; IEA:EC.
208C1KZ99    488   IOLA_LISMC Methylmalonate semialdehyde dehydr...4616e-30     126     26     44
GO:0018478; F:malonate-semialdehyde dehydrogenase (acetylating) activity; IEA:EC.::GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating) activity; IEA:EC.
209A4IPF5    483   IOLA2_GEOTN Methylmalonate semialdehyde dehyd...4436e-30     126     28     46
GO:0018478; F:malonate-semialdehyde dehydrogenase (acetylating) activity; IEA:EC.::GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating) activity; IEA:EC.
210Q1RB47    492   ASTD_ECOUT N-succinylglutamate 5-semialdehyde...4897e-30     126     28     46
GO:0043824; F:succinylglutamate-semialdehyde dehydrogenase activity; IEA:EC.
GO:0006527; P:arginine catabolic process; IEA:InterPro.
211B7MAV7    492   ASTD_ECO45 N-succinylglutamate 5-semialdehyde...4897e-30     126     28     46
GO:0043824; F:succinylglutamate-semialdehyde dehydrogenase activity; IEA:EC.
GO:0006527; P:arginine catabolic process; IEA:InterPro.
records
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