Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR030C
Length:
484
Number of sequences:
5887
Description:
YHR030C SLT2 SGDID:S000001072, Chr VIII from 170344-168890, Genome Release 64-1-1, reverse complement, Verified ORF, "Serine/threonine MAP kinase; involved in regulating maintenance of cell wall integrity, progression through the cell cycle, and nuclear mRNA retention in heat shock; required for mitophagy and pexophagy; affects recruitment of mitochondria to the phagophore assembly site (PAS); regulated by the PKC1-mediated signaling pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
751Q86Z02    1210   HIPK1_HUMAN Homeodomain-interacting protein k...3672e-18     92.4     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0060216; P:definitive hemopoiesis; ISS:UniProtKB.::GO:0001654; P:eye development; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0010803; P:regulation of tumor necrosis factor-mediated signaling pathway; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
752Q5R9Z7    970   PLK4_PONAB Serine/threonine-protein kinase PL...3032e-18     92     27     47GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
753Q07832    603   PLK1_MOUSE Serine/threonine-protein kinase PL...2102e-18     91.7     34     48GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007092; P:activation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0071168; P:protein localization to chromatin; ISS:UniProtKB.
754O74536    576   SNF1_SCHPO SNF1-like protein kinase ssp2 OS=S...2982e-18     91.7     26     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031593; F:polyubiquitin binding; TAS:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:2000766; P:negative regulation of cytoplasmic translation; ISS:PomBase.::GO:0046015; P:regulation of transcription by glucose; ISS:PomBase.::GO:0007165; P:signal transduction; IC:PomBase.
755P42818    465   KPK1_ARATH Serine/threonine-protein kinase At...3092e-18     90.9     27     43GO:0005737; C:cytoplasm; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0045727; P:positive regulation of translation; TAS:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
756P62343    524   CDPK1_PLAFK Calcium-dependent protein kinase ...3223e-18     91.3     26     43GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
757P62344    524   CDPK1_PLAF7 Calcium-dependent protein kinase ...3223e-18     91.3     26     43GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
758Q54YF2    727   AMPKA_DICDI 5'-AMP-activated serine/threonine...3043e-18     91.7     28     45
GO:0004679; F:AMP-activated protein kinase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006754; P:ATP biosynthetic process; IMP:dictyBase.::GO:0008283; P:cell proliferation; IMP:dictyBase.::GO:0007005; P:mitochondrion organization; IMP:dictyBase.::GO:0046956; P:positive phototaxis; IMP:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase.
759O00444    970   PLK4_HUMAN Serine/threonine-protein kinase PL...3033e-18     92     27     47GO:0005814; C:centriole; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; IMP:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0046601; P:positive regulation of centriole replication; IMP:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
760Q54QV3    1458   YAKA_DICDI Probable serine/threonine-protein ...2723e-18     92     30     49GO:0005829; C:cytosol; TAS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.
GO:0031152; P:aggregation involved in sorocarp development; TAS:dictyBase.::GO:0006935; P:chemotaxis; TAS:dictyBase.::GO:0007165; P:signal transduction; TAS:dictyBase.
761P51567    427   AFC2_ARATH Serine/threonine-protein kinase AF...3653e-18     90.5     24     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.
GO:0006397; P:mRNA processing; IDA:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.
762P28583    508   CDPK_SOYBN Calcium-dependent protein kinase S...3473e-18     91.3     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
763Q9P286    719   PAK7_HUMAN Serine/threonine-protein kinase PA...3093e-18     91.7     28     45GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0016049; P:cell growth; TAS:UniProtKB.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:UniProtKB.
764Q9UK32    745   KS6A6_HUMAN Ribosomal protein S6 kinase alpha...2330.00000000000002     79.7     27     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0045992; P:negative regulation of embryonic development; ISS:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:2000381; P:negative regulation of mesoderm development; ISS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome.
765Q62925    1493   M3K1_RAT Mitogen-activated protein kinase kin...3233e-18     92     27     43GO:0005737; C:cytoplasm; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008432; F:JUN kinase binding; IPI:RGD.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:RGD.::GO:0004710; F:MAPK/ERK kinase kinase activity; IDA:RGD.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:RGD.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:RGD.::GO:0046625; F:sphingolipid binding; IPI:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032232; P:negative regulation of actin filament bundle assembly; IDA:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0050434; P:positive regulation of viral transcription; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0051259; P:protein oligomerization; IDA:RGD.::GO:0000209; P:protein polyubiquitination; IMP:RGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IGI:RGD.::GO:0006970; P:response to osmotic stress; IMP:RGD.
766O88904    1210   HIPK1_MOUSE Homeodomain-interacting protein k...3673e-18     92     25     42GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016607; C:nuclear speck; IDA:MGI.::GO:0016605; C:PML body; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0048596; P:embryonic camera-type eye morphogenesis; IMP:DFLAT.::GO:0060059; P:embryonic retina morphogenesis in camera-type eye; IMP:DFLAT.::GO:0061072; P:iris morphogenesis; IMP:DFLAT.::GO:0060235; P:lens induction in camera-type eye; IMP:DFLAT.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030182; P:neuron differentiation; IMP:DFLAT.::GO:0008284; P:positive regulation of cell proliferation; IGI:MGI.::GO:0043388; P:positive regulation of DNA binding; ISS:UniProtKB.::GO:0010842; P:retina layer formation; IMP:DFLAT.::GO:0007224; P:smoothened signaling pathway; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
767Q9NRH2    765   SNRK_HUMAN SNF-related serine/threonine-prote...3973e-18     91.3     25     43GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0030099; P:myeloid cell differentiation; TAS:UniProtKB.
768A4L9P5    1211   HIPK1_RAT Homeodomain-interacting protein kin...3674e-18     91.7     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
769Q61XD3    302   AIR2_CAEBR Aurora/IPL1-related protein kinase...3144e-18     88.6     25     45GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
770Q5UPU3    546   YL268_MIMIV Putative serine/threonine-protein...3234e-18     90.9     29     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
771Q6PFQ0    740   KS6A6_DANRE Ribosomal protein S6 kinase alpha...2330.000000000000007     80.9     27     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.
772P27466    446   KCC1_YEAST Calcium/calmodulin-dependent prote...4544e-18     90.1     24     42GO:0005737; C:cytoplasm; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:SGD.
GO:0007165; P:signal transduction; IMP:SGD.
773Q54PX0    496   Y4251_DICDI Probable serine/threonine-protein...2964e-18     90.5     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
774Q01389    1478   BCK1_YEAST Serine/threonine-protein kinase BC...3014e-18     91.7     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IGI:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:SGD.::GO:0030010; P:establishment of cell polarity; IMP:SGD.::GO:0030242; P:peroxisome degradation; IMP:SGD.::GO:0001101; P:response to acid; IMP:SGD.::GO:0007584; P:response to nutrient; IMP:SGD.
775Q8IYT8    1036   ULK2_HUMAN Serine/threonine-protein kinase UL...2324e-18     91.3     29     48GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; IEA:InterPro.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0010506; P:regulation of autophagy; IDA:UniProtKB.::GO:0042594; P:response to starvation; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
776Q8VDF3    370   DAPK2_MOUSE Death-associated protein kinase 2...3415e-18     89     25     45GO:0034423; C:autophagic vacuole lumen; IEA:UniProtKB-SubCell.::GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.
777Q63184    513   E2AK2_RAT Interferon-induced, double-stranded...2345e-18     90.5     32     47GO:0005634; C:nucleus; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0033689; P:negative regulation of osteoblast proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0043330; P:response to exogenous dsRNA; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IMP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0009636; P:response to toxin; IMP:RGD.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0033197; P:response to vitamin E; IPI:RGD.
778B2GUY1    924   PLK4_RAT Serine/threonine-protein kinase PLK4...3025e-18     90.9     26     45GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
779P53349    1493   M3K1_MOUSE Mitogen-activated protein kinase k...3225e-18     91.3     27     43GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007257; P:activation of JUN kinase activity; IDA:BHF-UCL.
780O22932    435   CIPKB_ARATH CBL-interacting serine/threonine-...3355e-18     89.7     26     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009268; P:response to pH; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
781O44997    1425   DAPK_CAEEL Death-associated protein kinase da...3005e-18     91.3     25     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
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