Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR027C
Length:
993
Number of sequences:
5887
Description:
YHR027C RPN1 SGDID:S000001069, Chr VIII from 164711-161730, Genome Release 64-1-1, reverse complement, Verified ORF, "Non-ATPase base subunit of the 19S regulatory particle of the 26S proteasome; may participate in the recognition of several ligands of the proteasome; contains a leucine-rich repeat (LRR) domain, a site for protein-protein interactions"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38764    993   RPN1_YEAST 26S proteasome regulatory subunit ...9930     2033     100     100GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0008540; C:proteasome regulatory particle, base subcomplex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IDA:SGD.
GO:0030234; F:enzyme regulator activity; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IPI:SGD.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:SGD.
2Q6FPV6    983   RPN1_CANGA 26S proteasome regulatory subunit ...9980     1405     72     85GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
3P87048    891   RPN1_SCHPO 26S proteasome regulatory subunit ...9750     674     41     59GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:PomBase.
GO:0030234; F:enzyme regulator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.::GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
4Q7S8R8    902   RPN1_NEUCR 26S proteasome regulatory subunit ...2602e-101     345     62     80GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
5Q54BC6    893   PSMD2_DICDI 26S proteasome non-ATPase regulat...9642e-172     533     35     55GO:0005634; C:nucleus; ISS:dictyBase.::GO:0005838; C:proteasome regulatory particle; ISS:dictyBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0004175; F:endopeptidase activity; ISS:dictyBase.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0006972; P:hyperosmotic response; IEP:dictyBase.::GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:dictyBase.
6Q8VDM4    908   PSMD2_MOUSE 26S proteasome non-ATPase regulat...2541e-83     295     55     76GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0030234; F:enzyme regulator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
7Q4FZT9    908   PSMD2_RAT 26S proteasome non-ATPase regulator...2541e-83     295     55     76GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
8P56701    908   PSMD2_BOVIN 26S proteasome non-ATPase regulat...2541e-83     295     55     76GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
9Q13200    908   PSMD2_HUMAN 26S proteasome non-ATPase regulat...2541e-83     295     55     76GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.::GO:0005838; C:proteasome regulatory particle; TAS:ProtInc.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
10Q5R9I6    908   PSMD2_PONAB 26S proteasome non-ATPase regulat...2541e-83     295     55     76GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
11Q9SIV2    891   RPN1A_ARATH 26S proteasome non-ATPase regulat...2578e-75     269     49     73GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; TAS:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0000502; C:proteasome complex; IDA:TAIR.
GO:0030234; F:enzyme regulator activity; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
GO:0030163; P:protein catabolic process; TAS:TAIR.::GO:0051726; P:regulation of cell cycle; IMP:TAIR.::GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
12Q6XJG8    891   RPN1B_ARATH 26S proteasome non-ATPase regulat...2573e-72     262     49     72GO:0008540; C:proteasome regulatory particle, base subcomplex; TAS:TAIR.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; TAS:TAIR.::GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
13Q8SS65    795   RPN1_ENCCU 26S proteasome regulatory subunit ...5968e-27     121     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
14Q6FIP2    941   RPN2_CANGA 26S proteasome regulatory subunit ...2519.3     33.9     25     38GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
15P32565    945   RPN2_YEAST 26S proteasome regulatory subunit ...2720.00000004     61.2     26     45GO:0005634; C:nucleus; IDA:SGD.::GO:0008540; C:proteasome regulatory particle, base subcomplex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IDA:SGD.
GO:0030234; F:enzyme regulator activity; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IPI:SGD.
GO:0043248; P:proteasome assembly; IGI:SGD.::GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD.
16Q99460    953   PSMD1_HUMAN 26S proteasome non-ATPase regulat...1707.3     34.3     31     45GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005838; C:proteasome regulatory particle; TAS:ProtInc.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
17Q5R5S4    953   PSMD1_PONAB 26S proteasome non-ATPase regulat...1707.6     34.3     31     45GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
18Q3TXS7    953   PSMD1_MOUSE 26S proteasome non-ATPase regulat...1707.7     34.3     31     45GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
19Q5F418    955   PSMD1_CHICK 26S proteasome non-ATPase regulat...2470.00000005     60.8     26     45GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
20O88761    953   PSMD1_RAT 26S proteasome non-ATPase regulator...2490.00000006     60.8     27     46GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
21Q75CF3    930   RPN2_ASHGO 26S proteasome regulatory subunit ...2720.0000008     57     25     44GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
22Q18115    965   PSMD1_CAEEL 26S proteasome non-ATPase regulat...2540.00002     52     25     42GO:0005938; C:cell cortex; IDA:WormBase.::GO:0072686; C:mitotic spindle; IDA:WormBase.::GO:0031965; C:nuclear membrane; IDA:WormBase.::GO:0005886; C:plasma membrane; IDA:WormBase.::GO:0000502; C:proteasome complex; NAS:UniProtKB.
GO:0030234; F:enzyme regulator activity; IEA:InterPro.::GO:0005080; F:protein kinase C binding; IPI:WormBase.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.::GO:0000003; P:reproduction; IMP:WormBase.
23Q8SSH5    786   RPN2_ENCCU 26S proteasome regulatory subunit ...1200.00003     52     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
24Q54JM5    975   PSMD1_DICDI 26S proteasome non-ATPase regulat...2430.00005     51.2     25     45GO:0005813; C:centrosome; IDA:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase.::GO:0005838; C:proteasome regulatory particle; ISS:dictyBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0004175; F:endopeptidase activity; ISS:dictyBase.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:dictyBase.
25O74762    965   RPN2_SCHPO 26S proteasome regulatory subunit ...2510.0001     49.7     20     42GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:PomBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; NAS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.::GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
26Q9V3P6    1020   PSMD1_DROME 26S proteasome non-ATPase regulat...2460.89     37.4     23     43GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:FlyBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0004175; F:endopeptidase activity; IDA:FlyBase.::GO:0030234; F:enzyme regulator activity; IEA:InterPro.
GO:0006508; P:proteolysis; IDA:FlyBase.::GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.
27Q91ID6    561   VP6_LDCPR Microtubule-associated protein VP6 ...1142.4     35.8     28     46GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-KW.::GO:0044163; C:host cytoskeleton; IEA:UniProtKB-SubCell.::GO:0019012; C:virion; IEA:UniProtKB-SubCell.
28Q2NQH6    257   BIOH_SODGM Pimelyl-[acyl-carrier protein] met...1112.7     35     31     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
29Q9HNI8    280   PHNC_HALSA Phosphonates import ATP-binding pr...954.4     34.3     31     49GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015416; F:organic phosphonate transmembrane-transporting ATPase activity; IEA:EC.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
30Q9URV2    1458   APC1_SCHPO Anaphase-promoting complex subunit...1596.9     34.3     25     45GO:0005680; C:anaphase-promoting complex; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IC:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; IC:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016567; P:protein ubiquitination; IC:PomBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IC:PomBase.
31Q6SZS6    446   PYRD2_KLUMA Dihydroorotate dehydrogenase (qui...1287.6     33.9     31     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
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