Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR016C
Length:
468
Number of sequences:
5887
Description:
YHR016C YSC84 SGDID:S000001058, Chr VIII from 138240-136881,138455-138409, Genome Release 64-1-1, reverse complement, Verified ORF, "Actin-binding protein involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32793    468   YSC84_YEAST Protein YSC84 OS=Saccharomyces ce...4680     949     100     100GO:0030479; C:actin cortical patch; IDA:SGD.
GO:0051015; F:actin filament binding; IDA:SGD.
GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0051017; P:actin filament bundle assembly; IDA:SGD.::GO:0006897; P:endocytosis; IGI:SGD.
2P43603    459   LSB3_YEAST LAS seventeen-binding protein 3 OS...4791e-153     452     64     73GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051666; P:actin cortical patch localization; IMP:SGD.
3A7A261    459   LSB3_YEAS7 LAS seventeen-binding protein 3 OS...4791e-153     452     64     73GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
4Q9URW6    430   YIE2_SCHPO SH3 domain-containing protein PJ69...4793e-118     360     44     59GO:0030479; C:actin cortical patch; ISS:PomBase.
GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.
5Q96HL8    342   SH3Y1_HUMAN SH3 domain-containing YSC84-like ...590.00000000000007     76.3     58     71
6Q3SZ01    341   SH3Y1_BOVIN SH3 domain-containing YSC84-like ...590.000000000000009     78.6     59     73
7Q5RAQ2    342   SH3Y1_PONAB SH3 domain-containing YSC84-like ...590.00000000000007     76.3     58     71
8O08641    340   SH3Y1_MOUSE SH3 domain-containing YSC84-like ...800.0000000000003     74.3     48     61
GO:0005515; F:protein binding; IPI:IntAct.
9B0BNA1    340   SH3Y1_RAT SH3 domain-containing YSC84-like pr...640.00000000000007     76.3     52     67
10Q6DFH5    335   SH3Y1_XENLA SH3 domain-containing YSC84-like ...560.0000000000005     73.6     57     70
11O43125    296   CSH3_SCHPO Protein csh3 OS=Schizosaccharomyce...900.000000000003     70.5     38     53GO:0005737; C:cytoplasm; IDA:PomBase.
GO:0030036; P:actin cytoskeleton organization; ISS:PomBase.
12O74352    466   HOB1_SCHPO Protein hob1 OS=Schizosaccharomyce...540.000000000007     70.9     50     74GO:0051285; C:cell cortex of cell tip; TAS:PomBase.::GO:0031097; C:medial cortex; TAS:PomBase.
GO:0051020; F:GTPase binding; NAS:PomBase.
GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0006348; P:chromatin silencing at telomere; IMP:PomBase.::GO:0007163; P:establishment or maintenance of cell polarity; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0006974; P:response to DNA damage stimulus; IGI:PomBase.::GO:0000723; P:telomere maintenance; IMP:PomBase.
13P39743    482   RV167_YEAST Reduced viability upon starvation...550.00000000003     68.9     47     73GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0006897; P:endocytosis; IMP:SGD.::GO:0060988; P:lipid tube assembly; IDA:SGD.
14Q7S6J4    745   HSE1_NEUCR Class E vacuolar protein-sorting m...630.0000000001     67.4     52     67GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
15P29355    228   SEM5_CAEEL Sex muscle abnormal protein 5 OS=C...550.0001     47     36     62
GO:0016477; P:cell migration; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0030539; P:male genitalia development; IMP:WormBase.::GO:0007517; P:muscle organ development; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0031344; P:regulation of cell projection organization; IMP:WormBase.::GO:0040028; P:regulation of vulval development; IMP:WormBase.::GO:0032940; P:secretion by cell; IMP:WormBase.
16Q91X43    789   SH319_MOUSE SH3 domain-containing protein 19 ...660.029     40.8     32     58
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.
17Q2GT05    713   HSE1_CHAGB Class E vacuolar protein-sorting m...510.0000000003     65.9     57     67GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
18P53281    241   LSB1_YEAST LAS seventeen-binding protein 1 OS...770.0000000006     63.2     43     64GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
19Q6NRD3    826   SH3R1_XENLA E3 ubiquitin-protein ligase SH3RF...521.8     35     29     60GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
20Q28E95    861   SH3R1_XENTR E3 ubiquitin-protein ligase SH3RF...532.8     34.3     28     58GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
21Q7Z6J0    888   SH3R1_HUMAN E3 ubiquitin-protein ligase SH3RF...522.8     34.3     29     60GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.::GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
22Q5RBR0    888   SH3R1_PONAB E3 ubiquitin-protein ligase SH3RF...532.7     34.3     28     58GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
23Q71F54    894   SH3R1_RAT E3 ubiquitin-protein ligase SH3RF1 ...523     34.3     29     60GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006917; P:induction of apoptosis; IMP:RGD.
24Q8I1C0    369   SH3G3_DROPS Endophilin-A OS=Drosophila pseudo...640.000000001     63.5     42     63GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB.
GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB.
25Q8I190    369   SH3G3_DROVI Endophilin-A OS=Drosophila virili...640.000000002     62.8     42     61GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB.
GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB.
26P10569    1168   MYSC_ACACA Myosin IC heavy chain OS=Acanthamo...540.000000002     63.5     50     70GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
27Q75DS3    443   HSE1_ASHGO Class E vacuolar protein-sorting m...790.000000003     62.8     37     56GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
28Q4P5J4    593   HSE1_USTMA Class E vacuolar protein-sorting m...660.000000003     62.8     48     64GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
29Q5BBL4    581   HSE1_EMENI Class E vacuolar protein-sorting m...810.000000004     62.4     41     58GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
30Q69ZI1    892   SH3R1_MOUSE E3 ubiquitin-protein ligase SH3RF...512.5     34.3     29     61GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005078; F:MAP-kinase scaffold activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046328; P:regulation of JNK cascade; IDA:MGI.
31Q9Z0R4    1714   ITSN1_MOUSE Intersectin-1 OS=Mus musculus (Mo...490.16     38.5     33     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019209; F:kinase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.
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