Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR016C
Length:
468
Number of sequences:
5887
Description:
YHR016C YSC84 SGDID:S000001058, Chr VIII from 138240-136881,138455-138409, Genome Release 64-1-1, reverse complement, Verified ORF, "Actin-binding protein involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q6BNP6    512   HSE1_DEBHA Class E vacuolar protein-sorting m...780.00000005     58.9     40     56GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
62Q62420    352   SH3G2_MOUSE Endophilin-A1 OS=Mus musculus (Mo...560.00000005     58.2     43     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0002090; P:regulation of receptor internalization; IDA:MGI.::GO:0048488; P:synaptic vesicle endocytosis; IGI:MGI.
63O35179    352   SH3G2_RAT Endophilin-A1 OS=Rattus norvegicus ...560.00000006     58.2     43     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
64Q62421    347   SH3G3_MOUSE Endophilin-A3 OS=Mus musculus (Mo...920.00000006     58.2     36     50GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
65Q557J6    481   DBNL_DICDI Drebrin-like protein OS=Dictyostel...540.00000008     58.2     50     74GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0030864; C:cortical actin cytoskeleton; IDA:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0097203; C:phagocytic cup lip; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; ISS:dictyBase.::GO:0032037; F:myosin I heavy chain binding; IPI:dictyBase.::GO:0005522; F:profilin binding; IPI:dictyBase.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0050765; P:negative regulation of phagocytosis; IMP:dictyBase.::GO:0031269; P:pseudopodium assembly; IMP:dictyBase.
66A0JNJ1    403   STAC_BOVIN SH3 and cysteine-rich domain-conta...540.00000008     57.8     46     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
67Q06449    215   PIN3_YEAST [PSI+] inducibility protein 3 OS=S...670.00000008     56.2     42     61GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0030036; P:actin cytoskeleton organization; IPI:SGD.
68Q8TC17    118   GRAPL_HUMAN GRB2-related adapter protein-like...540.00000009     55.1     46     59
69Q99962    352   SH3G2_HUMAN Endophilin-A1 OS=Homo sapiens (Hu...560.0000001     57.4     43     61GO:0005829; C:cytosol; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
70Q9NZM3    1697   ITSN2_HUMAN Intersectin-2 OS=Homo sapiens (Hu...745.2     33.5     28     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
71Q8AXV1    353   SH3G2_CHICK Endophilin-A1 OS=Gallus gallus (C...560.0000001     57.4     43     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
72Q5HYK7    790   SH319_HUMAN SH3 domain-containing protein 19 ...520.003     43.9     40     65GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.
GO:0070064; F:proline-rich region binding; IPI:BHF-UCL.
GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
73Q498M5    735   SH3R2_RAT Putative E3 ubiquitin-protein ligas...600.056     39.7     38     48
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
74Q9Z0R6    1659   ITSN2_MOUSE Intersectin-2 OS=Mus musculus (Mo...742.2     34.7     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
75Q99963    347   SH3G3_HUMAN Endophilin-A3 OS=Homo sapiens (Hu...560.0000002     56.2     43     61GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.
76A4FU49    640   SH321_HUMAN SH3 domain-containing protein 21 ...500.0000002     56.6     38     62
77O35180    347   SH3G3_RAT Endophilin-A3 OS=Rattus norvegicus ...630.0000003     55.8     41     56GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
78Q9CX99    217   GRAP_MOUSE GRB2-related adapter protein OS=Mu...530.00002     49.3     34     64
79Q13588    217   GRAP_HUMAN GRB2-related adapter protein OS=Ho...530.0000006     53.5     40     68GO:0005829; C:cytosol; TAS:Reactome.
GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
80P0CR79    660   HSE1_CRYNB Class E vacuolar protein-sorting m...590.0000004     56.2     46     63GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
81Q07883    217   GRB2_CHICK Growth factor receptor-bound prote...550.0001     46.6     36     58GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
82Q6FN49    450   HSE1_CANGA Class E vacuolar protein-sorting m...500.0000005     55.5     48     66GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
83O00160    1098   MYO1F_HUMAN Unconventional myosin-If OS=Homo ...670.0000005     55.8     39     55GO:0016461; C:unconventional myosin complex; NAS:UniProtKB.
GO:0003779; F:actin binding; NAS:UniProtKB.::GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; NAS:UniProtKB.::GO:0003774; F:motor activity; IEA:InterPro.
84P0CR78    660   HSE1_CRYNJ Class E vacuolar protein-sorting m...510.0000006     55.8     47     65GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
85P14317    486   HCLS1_HUMAN Hematopoietic lineage cell-specif...550.0000007     55.1     45     67GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; TAS:ProtInc.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; ISS:UniProtKB.::GO:0009725; P:response to hormone stimulus; ISS:UniProtKB.
86O35964    368   SH3G1_RAT Endophilin-A2 OS=Rattus norvegicus ...560.0000007     54.7     41     66GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0051020; F:GTPase binding; IPI:RGD.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0019902; F:phosphatase binding; IPI:RGD.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
87Q62419    368   SH3G1_MOUSE Endophilin-A2 OS=Mus musculus (Mo...560.0000008     54.7     41     66GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
88A6QLK6    217   GRAP_BOVIN GRB2-related adapter protein OS=Bo...530.0000009     53.1     40     68
89O89100    322   GRAP2_MOUSE GRB2-related adaptor protein 2 OS...540.67     35.8     28     52GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:MGI.
90Q99961    368   SH3G1_HUMAN Endophilin-A2 OS=Homo sapiens (Hu...560.0000009     54.3     43     63GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.
91Q4R729    692   SH321_MACFA SH3 domain-containing protein 21 ...490.000001     55.1     37     61
records
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